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The map label for this gene is macB [H]

Identifier: 220916017

GI number: 220916017

Start: 1022439

End: 1023689

Strand: Reverse

Name: macB [H]

Synonym: A2cp1_0903

Alternate gene names: 220916017

Gene position: 1023689-1022439 (Counterclockwise)

Preceding gene: 220916018

Following gene: 220916015

Centisome position: 20.35

GC content: 74.74

Gene sequence:

>1251_bases
GTGGTGAACTGGGAGGCGATGCGCTCCTGGCTCGACGACGTCGGAATGGCCGCGGCCACGCTGCGAGCGAGCCCGCTCCG
CTCGCTGCTCACCGCGCTCGGCATCGTCATCGGCACCGCCACGGTGGTGGCGATGATGGCGCTCACCGAGGGGCTGCGGC
TGGAGATGACCGGCCAGCTCTCCATGCTGGAGGCGGGCGCGTTCCGGGTGGAGAAGTTCCCGATGGTCACGGTCGGCCAC
GAGGCGTGGCACCGGTACGCGAGCCGCAAGGACATCACCCGCGCCCAGGGCGAGGCGCTCCGCGGCCTCCCCCACGTCGC
GTTCGTGTCGATCGAGGAGCAGGGGCGCCGGCCCGAGGCCGTCGCCACGCGGACGCGCGCGACGCGCAACGAGATCGACG
TCCTCGGCGTGCTGCCGGACTACGAGTTCACCAACGCGGTGACGGTCTCGAGCGGGCGGTTCCTCTCGCACGCCGACGTG
GCGCTGGCGCGCCGCGTGGCCTTCGTGGGCGCGGGCGTCGCCGACGTGCTGTTCCCGGGGGCCGACGCGGTCGGCGCCGA
GATCCGGATCCGCGGCGTGCCGTTCGAGGTGGCTGGCGTGGCGGAGCGGATGGGGACCGTGCTCGGGCTCGAGTCGCGCG
ACGGGTTCGTGGCGGTCCCGTGGACCGCCTACGACGCGGTCCTGGGCCGGGCCCGCGGCACGAACCTCGCCGTCCGCGCC
ACGCGCGTGGAGGACGTGCCGCAGGCCATGGCCGAGGTGGTCGCGACGCTCCGCCGGGTCCGCGGGCTCGGCCCGCTCGA
GGAGAACGACTTCGAGGTGTTCTCGAACGACACCGCCGCGGAGCTGTTCGACGGGCTGGCGCGGGTGGTGGGCGCGGCCA
CGTTCGGCCTGTGCGCGCTCTCGCTGCTGGTGGGCGGCATCGGCGTGATGAACATCATGCTGGTCTCGGTGACCGAGCGG
ACCCGCGAGATCGGCGTGCGCATGGCGCTCGGGGCGCGGCGCGAGCGGATCCTGGCGCAGTTCCTGGTCGAGTCGCTGGT
GCTCGCGCTGGTGGGCGGCGCGATCGGCGTCGCGCTCGGCGGCGGGGTGGCGCTGGTGGCGCGGGAGCTGGACGTCGTGC
CGGCGCGCGTGCCGCTCTGGTCGGTGCTGCTGTCGCTCGGCTCCGCCGCCGCGGCGGGGCTGGTGTTCGGGATCTACCCC
GCGGCGCGCGCCTCCCGGCTCGATCCGGTCGAGGCGATGCGGGCGGAGTAG

Upstream 100 bases:

>100_bases
ATCCGGCCCGACCCGCCGCGCGCCGCCGCGGCCTGAGGGTCCGTGGCGACACCGACGTCGCGCCCCACCGGCGATCGGGG
CGTGACGCTGGCGGCGTGGC

Downstream 100 bases:

>100_bases
CGCGCGCCCCGCGGTCCGGGCTCCGGCTCAGGGGGGCAGGTACCAGACCACGGCCACGATGACGGGCTGGTCCACCGGCG
GGCGCGGGTACGGTGCGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MVNWEAMRSWLDDVGMAAATLRASPLRSLLTALGIVIGTATVVAMMALTEGLRLEMTGQLSMLEAGAFRVEKFPMVTVGH
EAWHRYASRKDITRAQGEALRGLPHVAFVSIEEQGRRPEAVATRTRATRNEIDVLGVLPDYEFTNAVTVSSGRFLSHADV
ALARRVAFVGAGVADVLFPGADAVGAEIRIRGVPFEVAGVAERMGTVLGLESRDGFVAVPWTAYDAVLGRARGTNLAVRA
TRVEDVPQAMAEVVATLRRVRGLGPLEENDFEVFSNDTAAELFDGLARVVGAATFGLCALSLLVGGIGVMNIMLVSVTER
TREIGVRMALGARRERILAQFLVESLVLALVGGAIGVALGGGVALVARELDVVPARVPLWSVLLSLGSAAAAGLVFGIYP
AARASRLDPVEAMRAE

Sequences:

>Translated_416_residues
MVNWEAMRSWLDDVGMAAATLRASPLRSLLTALGIVIGTATVVAMMALTEGLRLEMTGQLSMLEAGAFRVEKFPMVTVGH
EAWHRYASRKDITRAQGEALRGLPHVAFVSIEEQGRRPEAVATRTRATRNEIDVLGVLPDYEFTNAVTVSSGRFLSHADV
ALARRVAFVGAGVADVLFPGADAVGAEIRIRGVPFEVAGVAERMGTVLGLESRDGFVAVPWTAYDAVLGRARGTNLAVRA
TRVEDVPQAMAEVVATLRRVRGLGPLEENDFEVFSNDTAAELFDGLARVVGAATFGLCALSLLVGGIGVMNIMLVSVTER
TREIGVRMALGARRERILAQFLVESLVLALVGGAIGVALGGGVALVARELDVVPARVPLWSVLLSLGSAAAAGLVFGIYP
AARASRLDPVEAMRAE
>Mature_416_residues
MVNWEAMRSWLDDVGMAAATLRASPLRSLLTALGIVIGTATVVAMMALTEGLRLEMTGQLSMLEAGAFRVEKFPMVTVGH
EAWHRYASRKDITRAQGEALRGLPHVAFVSIEEQGRRPEAVATRTRATRNEIDVLGVLPDYEFTNAVTVSSGRFLSHADV
ALARRVAFVGAGVADVLFPGADAVGAEIRIRGVPFEVAGVAERMGTVLGLESRDGFVAVPWTAYDAVLGRARGTNLAVRA
TRVEDVPQAMAEVVATLRRVRGLGPLEENDFEVFSNDTAAELFDGLARVVGAATFGLCALSLLVGGIGVMNIMLVSVTER
TREIGVRMALGARRERILAQFLVESLVLALVGGAIGVALGGGVALVARELDVVPARVPLWSVLLSLGSAAAAGLVFGIYP
AARASRLDPVEAMRAE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=420, Percent_Identity=30.952380952381, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44067; Mature: 44067

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNWEAMRSWLDDVGMAAATLRASPLRSLLTALGIVIGTATVVAMMALTEGLRLEMTGQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SMLEAGAFRVEKFPMVTVGHEAWHRYASRKDITRAQGEALRGLPHVAFVSIEEQGRRPEA
HHHHHCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCHH
VATRTRATRNEIDVLGVLPDYEFTNAVTVSSGRFLSHADVALARRVAFVGAGVADVLFPG
HHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHCCC
ADAVGAEIRIRGVPFEVAGVAERMGTVLGLESRDGFVAVPWTAYDAVLGRARGTNLAVRA
CCCCCCEEEEECCCCHHHHHHHHHHHHEEECCCCCEEEECHHHHHHHHHCCCCCCEEEEE
TRVEDVPQAMAEVVATLRRVRGLGPLEENDFEVFSNDTAAELFDGLARVVGAATFGLCAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
SLLVGGIGVMNIMLVSVTERTREIGVRMALGARRERILAQFLVESLVLALVGGAIGVALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGVALVARELDVVPARVPLWSVLLSLGSAAAAGLVFGIYPAARASRLDPVEAMRAE
CCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MVNWEAMRSWLDDVGMAAATLRASPLRSLLTALGIVIGTATVVAMMALTEGLRLEMTGQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SMLEAGAFRVEKFPMVTVGHEAWHRYASRKDITRAQGEALRGLPHVAFVSIEEQGRRPEA
HHHHHCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCHH
VATRTRATRNEIDVLGVLPDYEFTNAVTVSSGRFLSHADVALARRVAFVGAGVADVLFPG
HHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHCCC
ADAVGAEIRIRGVPFEVAGVAERMGTVLGLESRDGFVAVPWTAYDAVLGRARGTNLAVRA
CCCCCCEEEEECCCCHHHHHHHHHHHHEEECCCCCEEEECHHHHHHHHHCCCCCCEEEEE
TRVEDVPQAMAEVVATLRRVRGLGPLEENDFEVFSNDTAAELFDGLARVVGAATFGLCAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
SLLVGGIGVMNIMLVSVTERTREIGVRMALGARRERILAQFLVESLVLALVGGAIGVALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGVALVARELDVVPARVPLWSVLLSLGSAAAAGLVFGIYPAARASRLDPVEAMRAE
CCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA