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The map label for this gene is oxlT [H]

Identifier: 220915986

GI number: 220915986

Start: 984388

End: 985749

Strand: Reverse

Name: oxlT [H]

Synonym: A2cp1_0872

Alternate gene names: 220915986

Gene position: 985749-984388 (Counterclockwise)

Preceding gene: 220915987

Following gene: 220915985

Centisome position: 19.6

GC content: 72.1

Gene sequence:

>1362_bases
ATGACGTCGAACCGCTGGTTCATCGCGGTGGCCGGCACCATCACCATGGCGTGCCTCGGCACCGTCTACTCGTGGAGCCT
GTTCACCCAGCCGCTCATCGCGGCGTTCGGCTGGTCCAGCACCACCACCACATGGGCGTTCGCGCTCTCGATCTTCTTCC
TGGGCGTGGGCGCGATCCTGGGCGGCCGCTGGCAGGACCGCTCCGGGCCGCGGCCGGTGGCGGTCACGGGCATCGTGCTG
TGGGGCCTCGGGAACGTGCTCGCCGGGCTGGGGACGGCGCGCTTCGGGGCGCCCTGGATCTACGCCACGTACGGCGTGAT
CGGCGGCCTGGGGCTGGGGCTCGGGTACGTGACCCCGGTCGCGGCGGTGACGAAGTGGTTCCCGGACAAGCGCGGTCTCG
GGACCGGCATGGTGGTGATGGGCTTCGGCCTGGGCGCGTTCATCTACAACAACCTGCTGAAGAACGTCGCCGCCTTCGCC
GAGGCGTCGCGCGAGGCCGGCCGGGTCCTCGCGGCGCGGCACGCGGGCGACGCGGCCGCGGCCATGTCGCCGGGCGCGAT
CTCGACCGTGATGCAGACGTTCCTCTGGTCCGGGGTGGTGTTCGCCGTGGTCGGCGGCATCTGCGCGCTGGCCATGCGCA
ACCCGACCGCGGTGGTGCCCGCGCCCGCCGCAGGCGCCGCGGCGTCGCCCGCGCCCGCCGCCGCGCCCGCGGTCCGCGTG
GCGCGCGACTACCCGCCCTCGGAGGCGCTGCGCACGCCGCAGTTCTGGGCGCTCTGGGCGATGCTGTTCCTGAACGTCAC
CGCCGGCATCCTGTTCATCTCGAACGCGGTGCCCATCATGCGCGAGCTCACCGGCGCCTCGCCCGAGAGCGCGCTGGCCG
TCTACGGCTTCATCGCGCTGTTCAACGGCCTGGGCCGCTTCTTCTGGGGCGCGATCTCGGATCGCATCGGCCGCAACCTC
GCCTACCTGCTCATCTACGGCTCGCAGGTCGTCATCTTCTTCGCCGTGGGCGGCGTCCACTCGCTGCCGCTGGTCGCGCT
CCTGTTCGCGATCGTCCTGCTCGACTACGGCGGCGGGTTCGGCACCATGCCCTCGTTCACCGCCGACTACTTTGGCACGA
AGTACATGGGCGTGAACTACGGGTGGATCCTCCTGGCCTGGGGCGTGGGCGGCATCGTCGGCCCCATCTTCGTGGCGCGG
GTGAAGGACCTCACCGGCTCGTTCTCCGGCGCGCTGCCGGTGATCGCGGTCATGCTGCTCGTCGCGGCCATCCTGCCGAT
CGTCACGCGGCGACCGGGGGCGGCGCGCGACGAGGGCAGCCGCTGGCGTCACCTGATGCCGCCGCGGCGCGTGCACGCCT
GA

Upstream 100 bases:

>100_bases
CGCGGGGTCCGGGCTGGTGCTCCTGCCCATGCGCGGCCTCGGCGGGTGATCGGGGCCGGCGGCGCAGGACGTGCCGCCGG
TGAGGGGAAGGGGGAGGGAC

Downstream 100 bases:

>100_bases
GCCCTCGCCTCCGGCGAGCCTCCGGCCTGCCGGCGCTCGGGGTGAGCGGATCGGACGCGCCCATCCCGAGCGCAGCGCCG
CGAGGCCAGGCGGCGCGCAG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTSNRWFIAVAGTITMACLGTVYSWSLFTQPLIAAFGWSSTTTTWAFALSIFFLGVGAILGGRWQDRSGPRPVAVTGIVL
WGLGNVLAGLGTARFGAPWIYATYGVIGGLGLGLGYVTPVAAVTKWFPDKRGLGTGMVVMGFGLGAFIYNNLLKNVAAFA
EASREAGRVLAARHAGDAAAAMSPGAISTVMQTFLWSGVVFAVVGGICALAMRNPTAVVPAPAAGAAASPAPAAAPAVRV
ARDYPPSEALRTPQFWALWAMLFLNVTAGILFISNAVPIMRELTGASPESALAVYGFIALFNGLGRFFWGAISDRIGRNL
AYLLIYGSQVVIFFAVGGVHSLPLVALLFAIVLLDYGGGFGTMPSFTADYFGTKYMGVNYGWILLAWGVGGIVGPIFVAR
VKDLTGSFSGALPVIAVMLLVAAILPIVTRRPGAARDEGSRWRHLMPPRRVHA

Sequences:

>Translated_453_residues
MTSNRWFIAVAGTITMACLGTVYSWSLFTQPLIAAFGWSSTTTTWAFALSIFFLGVGAILGGRWQDRSGPRPVAVTGIVL
WGLGNVLAGLGTARFGAPWIYATYGVIGGLGLGLGYVTPVAAVTKWFPDKRGLGTGMVVMGFGLGAFIYNNLLKNVAAFA
EASREAGRVLAARHAGDAAAAMSPGAISTVMQTFLWSGVVFAVVGGICALAMRNPTAVVPAPAAGAAASPAPAAAPAVRV
ARDYPPSEALRTPQFWALWAMLFLNVTAGILFISNAVPIMRELTGASPESALAVYGFIALFNGLGRFFWGAISDRIGRNL
AYLLIYGSQVVIFFAVGGVHSLPLVALLFAIVLLDYGGGFGTMPSFTADYFGTKYMGVNYGWILLAWGVGGIVGPIFVAR
VKDLTGSFSGALPVIAVMLLVAAILPIVTRRPGAARDEGSRWRHLMPPRRVHA
>Mature_452_residues
TSNRWFIAVAGTITMACLGTVYSWSLFTQPLIAAFGWSSTTTTWAFALSIFFLGVGAILGGRWQDRSGPRPVAVTGIVLW
GLGNVLAGLGTARFGAPWIYATYGVIGGLGLGLGYVTPVAAVTKWFPDKRGLGTGMVVMGFGLGAFIYNNLLKNVAAFAE
ASREAGRVLAARHAGDAAAAMSPGAISTVMQTFLWSGVVFAVVGGICALAMRNPTAVVPAPAAGAAASPAPAAAPAVRVA
RDYPPSEALRTPQFWALWAMLFLNVTAGILFISNAVPIMRELTGASPESALAVYGFIALFNGLGRFFWGAISDRIGRNLA
YLLIYGSQVVIFFAVGGVHSLPLVALLFAIVLLDYGGGFGTMPSFTADYFGTKYMGVNYGWILLAWGVGGIVGPIFVARV
KDLTGSFSGALPVIAVMLLVAAILPIVTRRPGAARDEGSRWRHLMPPRRVHA

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=401, Percent_Identity=27.6807980049875, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281360217, Length=151, Percent_Identity=31.7880794701987, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573971, Length=151, Percent_Identity=31.7880794701987, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47546; Mature: 47415

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNRWFIAVAGTITMACLGTVYSWSLFTQPLIAAFGWSSTTTTWAFALSIFFLGVGAIL
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GGRWQDRSGPRPVAVTGIVLWGLGNVLAGLGTARFGAPWIYATYGVIGGLGLGLGYVTPV
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AAVTKWFPDKRGLGTGMVVMGFGLGAFIYNNLLKNVAAFAEASREAGRVLAARHAGDAAA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AMSPGAISTVMQTFLWSGVVFAVVGGICALAMRNPTAVVPAPAAGAAASPAPAAAPAVRV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHH
ARDYPPSEALRTPQFWALWAMLFLNVTAGILFISNAVPIMRELTGASPESALAVYGFIAL
HCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHH
FNGLGRFFWGAISDRIGRNLAYLLIYGSQVVIFFAVGGVHSLPLVALLFAIVLLDYGGGF
HHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCC
GTMPSFTADYFGTKYMGVNYGWILLAWGVGGIVGPIFVARVKDLTGSFSGALPVIAVMLL
CCCCCCHHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VAAILPIVTRRPGAARDEGSRWRHLMPPRRVHA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
TSNRWFIAVAGTITMACLGTVYSWSLFTQPLIAAFGWSSTTTTWAFALSIFFLGVGAIL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH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HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]