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The map label for this gene is rho [H]

Identifier: 220915843

GI number: 220915843

Start: 816328

End: 817581

Strand: Reverse

Name: rho [H]

Synonym: A2cp1_0726

Alternate gene names: 220915843

Gene position: 817581-816328 (Counterclockwise)

Preceding gene: 220915852

Following gene: 220915842

Centisome position: 16.26

GC content: 67.22

Gene sequence:

>1254_bases
ATGAAGGTCGCGGAGCTCGCCAAGCTGGCGCGCGACCTCAACGTCGAGGCCGCCGGCGCGCTCAAGAAGCAGGACCTCAT
CTTCGCGATCCTCCAGGCGCAGTCGAAGGCGGCGGAGGCGGCCAAGGAGGAGATGGAGGTCGGCGGCGAGGGCACGCTGG
AGGTGCTGCCCGACGGCTTCGGCTTCCTGCGCAGCCCGGACTTCTCCTACCTGCCGGGCCCGGACGACATCTACGTCTCG
CCCTCGCAGATCCGCCGCTTCAACCTGCGCACCGGCGACACGGTGCGCGGCACGGTGCGCCAGCCCAAGGAAGGCGAGCG
CTACTTCGCGCTGCTCAAGGTCGACACCATCAACGGCGAGCCGCCCGAGGAGAACCAGGCCAAGGTCCTCTTCGACAACC
TGACCCCGCTCTACCCGACGCAGCGCCTGACGCTCGAGCACGATCCCGCCGAGATGACCACGCGGGTGGTGGACCTGTTC
GCGCCCATCGGCAAGGGGCAGCGCTGCCTGATCGTGTCGCCGCCGCGCGCCGGCAAGACGGTGCTCCTGCAGAACATCGC
GCACGCCGTCACCACCAACCACCCCGAGTGCACCCTCATCGTGCTGCTCATCGACGAGCGGCCCGAGGAGGTCACCGACA
TGGAGCGGACGGTGCGGGGCGAGGTGGTCGCCTCCACCTTCGACGAGCCCGCCACCCGCCACGTGCAGGTCGCGGAGATG
GTGATCGAGAAGGCCCGGCGGCTGGTCGAGCACAAGAAGGACGTGGTGATCCTGCTCGACTCGATCACCCGCCTCGCGCG
CGCCTACAACTCGACCGTGCCGCCCTCCGGGAAGATCCTCTCCGGCGGCGTGGACTCGAACGCGCTGCACAAGCCGAAGC
GCTTCTTCGGCGCGGCCCGCAACATCGAGGAGGGCGGCTCGCTCACCATCATCGGCACCGCGCTGGTGGACACCGGCAGC
CGCATGGACGAGGTGATCTTCGAGGAGTTCAAGGGCACCGGGAACTCCGAGATCGTGCTCGACCGCAAGCTGATGGAGAA
GCGCATCTTCCCCTGCATGGACATCGGGAAGAGCGGCACGCGCAAGGAGGAGCTGCTCCTCGCGGCCGACTGGCTCTCCA
AGATCTACATCCTGCGCCAGACCATCCTGAACGGCCTCGACAACGTCGAGGCGATGAAGTTCATCCTGGACAAGTTCCGC
CAGGTGAAGAACCACGACGAGTTCTTCAAGATGATGGTCGGCGGCGGCAAGTAG

Upstream 100 bases:

>100_bases
CACGCTCCGCAGCGCGCGGCCCAGCTCCCCGAGAACCGACATGCCCGCAGCCGCACCGACCTCCACGTCGAGCACGTCCA
GCCTCACCGAGCTCAAGCAC

Downstream 100 bases:

>100_bases
CGGCGGCTCGCCCGCAGGGGGGAGTCCCCGCCCGCGGCGCGCTCCGCTTGACCTATCCCCGCGATCCGACTAGATCCCGC
CGTTCCACAACCGGGCCCGG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKVAELAKLARDLNVEAAGALKKQDLIFAILQAQSKAAEAAKEEMEVGGEGTLEVLPDGFGFLRSPDFSYLPGPDDIYVS
PSQIRRFNLRTGDTVRGTVRQPKEGERYFALLKVDTINGEPPEENQAKVLFDNLTPLYPTQRLTLEHDPAEMTTRVVDLF
APIGKGQRCLIVSPPRAGKTVLLQNIAHAVTTNHPECTLIVLLIDERPEEVTDMERTVRGEVVASTFDEPATRHVQVAEM
VIEKARRLVEHKKDVVILLDSITRLARAYNSTVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIGTALVDTGS
RMDEVIFEEFKGTGNSEIVLDRKLMEKRIFPCMDIGKSGTRKEELLLAADWLSKIYILRQTILNGLDNVEAMKFILDKFR
QVKNHDEFFKMMVGGGK

Sequences:

>Translated_417_residues
MKVAELAKLARDLNVEAAGALKKQDLIFAILQAQSKAAEAAKEEMEVGGEGTLEVLPDGFGFLRSPDFSYLPGPDDIYVS
PSQIRRFNLRTGDTVRGTVRQPKEGERYFALLKVDTINGEPPEENQAKVLFDNLTPLYPTQRLTLEHDPAEMTTRVVDLF
APIGKGQRCLIVSPPRAGKTVLLQNIAHAVTTNHPECTLIVLLIDERPEEVTDMERTVRGEVVASTFDEPATRHVQVAEM
VIEKARRLVEHKKDVVILLDSITRLARAYNSTVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIGTALVDTGS
RMDEVIFEEFKGTGNSEIVLDRKLMEKRIFPCMDIGKSGTRKEELLLAADWLSKIYILRQTILNGLDNVEAMKFILDKFR
QVKNHDEFFKMMVGGGK
>Mature_417_residues
MKVAELAKLARDLNVEAAGALKKQDLIFAILQAQSKAAEAAKEEMEVGGEGTLEVLPDGFGFLRSPDFSYLPGPDDIYVS
PSQIRRFNLRTGDTVRGTVRQPKEGERYFALLKVDTINGEPPEENQAKVLFDNLTPLYPTQRLTLEHDPAEMTTRVVDLF
APIGKGQRCLIVSPPRAGKTVLLQNIAHAVTTNHPECTLIVLLIDERPEEVTDMERTVRGEVVASTFDEPATRHVQVAEM
VIEKARRLVEHKKDVVILLDSITRLARAYNSTVPPSGKILSGGVDSNALHKPKRFFGAARNIEEGGSLTIIGTALVDTGS
RMDEVIFEEFKGTGNSEIVLDRKLMEKRIFPCMDIGKSGTRKEELLLAADWLSKIYILRQTILNGLDNVEAMKFILDKFR
QVKNHDEFFKMMVGGGK

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=413, Percent_Identity=64.1646489104116, Blast_Score=556, Evalue=1e-159,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 46326; Mature: 46326

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAELAKLARDLNVEAAGALKKQDLIFAILQAQSKAAEAAKEEMEVGGEGTLEVLPDGF
CCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
GFLRSPDFSYLPGPDDIYVSPSQIRRFNLRTGDTVRGTVRQPKEGERYFALLKVDTINGE
CCCCCCCCCCCCCCCCEEECHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCC
PPEENQAKVLFDNLTPLYPTQRLTLEHDPAEMTTRVVDLFAPIGKGQRCLIVSPPRAGKT
CCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
VLLQNIAHAVTTNHPECTLIVLLIDERPEEVTDMERTVRGEVVASTFDEPATRHVQVAEM
HHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VIEKARRLVEHKKDVVILLDSITRLARAYNSTVPPSGKILSGGVDSNALHKPKRFFGAAR
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCHHHHHHHC
NIEEGGSLTIIGTALVDTGSRMDEVIFEEFKGTGNSEIVLDRKLMEKRIFPCMDIGKSGT
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCHHCCCCCCC
RKEELLLAADWLSKIYILRQTILNGLDNVEAMKFILDKFRQVKNHDEFFKMMVGGGK
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
>Mature Secondary Structure
MKVAELAKLARDLNVEAAGALKKQDLIFAILQAQSKAAEAAKEEMEVGGEGTLEVLPDGF
CCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
GFLRSPDFSYLPGPDDIYVSPSQIRRFNLRTGDTVRGTVRQPKEGERYFALLKVDTINGE
CCCCCCCCCCCCCCCCEEECHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCC
PPEENQAKVLFDNLTPLYPTQRLTLEHDPAEMTTRVVDLFAPIGKGQRCLIVSPPRAGKT
CCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
VLLQNIAHAVTTNHPECTLIVLLIDERPEEVTDMERTVRGEVVASTFDEPATRHVQVAEM
HHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VIEKARRLVEHKKDVVILLDSITRLARAYNSTVPPSGKILSGGVDSNALHKPKRFFGAAR
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCHHHHHHHC
NIEEGGSLTIIGTALVDTGSRMDEVIFEEFKGTGNSEIVLDRKLMEKRIFPCMDIGKSGT
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCHHCCCCCCC
RKEELLLAADWLSKIYILRQTILNGLDNVEAMKFILDKFRQVKNHDEFFKMMVGGGK
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]