Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 220915810

GI number: 220915810

Start: 777797

End: 778714

Strand: Reverse

Name: aroB [H]

Synonym: A2cp1_0693

Alternate gene names: 220915810

Gene position: 778714-777797 (Counterclockwise)

Preceding gene: 220915811

Following gene: 220915809

Centisome position: 15.48

GC content: 79.63

Gene sequence:

>918_bases
ATGGCCGGGCGGCTCGCCTCGATCGACGTCGGCACCAACACGGTGCTGCTGCTCGTGGCGGAGCGGCGCGGCGACGCGCT
CGCGCCGGTGCGGGAGCGCGCCGAGATCACCCGGCTCGGCCGCGGCGTGGACGCGACCGGACGCCTCGATCCGGCCGCCA
TCCGCGAGACCGTGGCCACGCTGGCGGCGTTCGCGGCGGAGGCCCGGGCGCTCGGCGCCGACGAGATCGCCTGCGTCGCC
ACCAGCGCCGCCCGCGACGCCGCGAACGGCGACGAGTTCTTCGAGGCGGCGCGCGCCGCGGCGGGGCTCTCGCCGCGGGT
CATCTCCGGCGACGAGGAGGCGCGCCTGGTCTACGGCAGCGCCTTCCGCGACTTCGGCGCGGGCGGGCCGCTCGCGGTGC
TCGACGTGGGCGGGGGCTCGACCGAGTTCATCGTGGGCGAGGACCCCGTGCCGCGCGCGCGCGTGAGCCTGCAGGTGGGC
GCGGTCCGGCTCACCGAGCGGCACGTGCGCGCCGATCCGGTGCGGGCCGAGGAGCTCGCGGCGATGCGCGCCGGGGCGCG
CGCGGCGCTCGCGCCGCTCGCCGCGCTGGGCGCGGGCGCCGGCGCGCGGCTGGTCGGCGTGGCGGGCACGGTGACCACCC
TCTCGGCCGTGGCGCAGGCGCTGCCCGCCTACGACGCGGAGCGCGTGCACGGGGCGGAGCTCCGGCTCGAGGAGGTGGAG
CGGCTGCTCGCGCGCCTCGCGGCGCTGCCGGTGGCGGCGCGCGCGGCGCTGCCCGGGATGGAGCCGAAGCGGGCCGACGT
GATCCTGGGCGGCGCGGTGGTGGTCGCGGAGGCGATGCGCCTCGCGGGCTTCGACCGGCTGACGGTCTCGGACCGCGGCG
TGCGCTGGGGGCTGCTCTACGAGCTCGCCGGTCCGTGA

Upstream 100 bases:

>100_bases
TGTCGGACGCGCGCGGCGACCGCCAGACGCCGGTGACGAGCGGCAAGACCGACCTGGCCGCGCCGGCCTGGGGCCCGCTG
GCGCCGTAGGCGGGGACGGC

Downstream 100 bases:

>100_bases
CGGCGCCGCCCGGCTCTACGCGGCGGTGGCCTTCGGGCCGGCCGCGGCGGTGTACGCGTTCCTGGTCGACCAGCCTGCGT
GGCGCGAGGACTGCCGCGCG

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAGRLASIDVGTNTVLLLVAERRGDALAPVRERAEITRLGRGVDATGRLDPAAIRETVATLAAFAAEARALGADEIACVA
TSAARDAANGDEFFEAARAAAGLSPRVISGDEEARLVYGSAFRDFGAGGPLAVLDVGGGSTEFIVGEDPVPRARVSLQVG
AVRLTERHVRADPVRAEELAAMRAGARAALAPLAALGAGAGARLVGVAGTVTTLSAVAQALPAYDAERVHGAELRLEEVE
RLLARLAALPVAARAALPGMEPKRADVILGGAVVVAEAMRLAGFDRLTVSDRGVRWGLLYELAGP

Sequences:

>Translated_305_residues
MAGRLASIDVGTNTVLLLVAERRGDALAPVRERAEITRLGRGVDATGRLDPAAIRETVATLAAFAAEARALGADEIACVA
TSAARDAANGDEFFEAARAAAGLSPRVISGDEEARLVYGSAFRDFGAGGPLAVLDVGGGSTEFIVGEDPVPRARVSLQVG
AVRLTERHVRADPVRAEELAAMRAGARAALAPLAALGAGAGARLVGVAGTVTTLSAVAQALPAYDAERVHGAELRLEEVE
RLLARLAALPVAARAALPGMEPKRADVILGGAVVVAEAMRLAGFDRLTVSDRGVRWGLLYELAGP
>Mature_304_residues
AGRLASIDVGTNTVLLLVAERRGDALAPVRERAEITRLGRGVDATGRLDPAAIRETVATLAAFAAEARALGADEIACVAT
SAARDAANGDEFFEAARAAAGLSPRVISGDEEARLVYGSAFRDFGAGGPLAVLDVGGGSTEFIVGEDPVPRARVSLQVGA
VRLTERHVRADPVRAEELAAMRAGARAALAPLAALGAGAGARLVGVAGTVTTLSAVAQALPAYDAERVHGAELRLEEVER
LLARLAALPVAARAALPGMEPKRADVILGGAVVVAEAMRLAGFDRLTVSDRGVRWGLLYELAGP

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=296, Percent_Identity=27.7027027027027, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788848, Length=301, Percent_Identity=24.2524916943522, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 31263; Mature: 31132

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRLASIDVGTNTVLLLVAERRGDALAPVRERAEITRLGRGVDATGRLDPAAIRETVAT
CCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LAAFAAEARALGADEIACVATSAARDAANGDEFFEAARAAAGLSPRVISGDEEARLVYGS
HHHHHHHHHHCCCCHHHEEECHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCEEEEEC
AFRDFGAGGPLAVLDVGGGSTEFIVGEDPVPRARVSLQVGAVRLTERHVRADPVRAEELA
HHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECEEEEHHHHHCCCCCCHHHHH
AMRAGARAALAPLAALGAGAGARLVGVAGTVTTLSAVAQALPAYDAERVHGAELRLEEVE
HHHHCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHH
RLLARLAALPVAARAALPGMEPKRADVILGGAVVVAEAMRLAGFDRLTVSDRGVRWGLLY
HHHHHHHHCCHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHCCCCEEEECCCCCEEEEEE
ELAGP
EECCC
>Mature Secondary Structure 
AGRLASIDVGTNTVLLLVAERRGDALAPVRERAEITRLGRGVDATGRLDPAAIRETVAT
CCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LAAFAAEARALGADEIACVATSAARDAANGDEFFEAARAAAGLSPRVISGDEEARLVYGS
HHHHHHHHHHCCCCHHHEEECHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCEEEEEC
AFRDFGAGGPLAVLDVGGGSTEFIVGEDPVPRARVSLQVGAVRLTERHVRADPVRAEELA
HHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECEEEEHHHHHCCCCCCHHHHH
AMRAGARAALAPLAALGAGAGARLVGVAGTVTTLSAVAQALPAYDAERVHGAELRLEEVE
HHHHCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHH
RLLARLAALPVAARAALPGMEPKRADVILGGAVVVAEAMRLAGFDRLTVSDRGVRWGLLY
HHHHHHHHCCHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHCCCCEEEECCCCCEEEEEE
ELAGP
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]