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The map label for this gene is rapA [H]

Identifier: 220915713

GI number: 220915713

Start: 666824

End: 669520

Strand: Direct

Name: rapA [H]

Synonym: A2cp1_0594

Alternate gene names: 220915713

Gene position: 666824-669520 (Clockwise)

Preceding gene: 220915711

Following gene: 220915716

Centisome position: 13.26

GC content: 75.94

Gene sequence:

>2697_bases
ATGGCCTGGAAAGCAGGGATGAAGGTGGTCCACCGCGCCCAGCGGGCATGGGGCGTGGGGGTGGTGGTGCAGGTCGCCGA
CGAGGGCCGCCGCCTGGCGGTCCGGTTCGCGGGCCGCGAGGGCATCACGGTGGTCTCGGGCCGCGATCAGGCGCTGGTCG
AGGTCCCGGCGGACACGCCGATCGAGCAGGTGGCCTCGGGACCGATCGAGGCGCTGGGCTCGGCCCAGCCGGCGACGGCC
TCGGCGTTCGCGCTCCGCACCCGCGTGAACCGCCTGGAGGCGCTGCGCCGCGCGGACTCGCTCGGCGCGCTGCTCTCCTC
GCGCGTGCACGTCCTGCCGCACCAGGTGGGCGCGGCGGGGCGCATCCTGTCCGATCGCATGCCGCGCTTCGTCCTGGCGG
ACGAGGTGGGCCTGGGCAAGACGGTCGAGGCGGGCCTGGTGTTCGCGGGCATGCGGCAGCTCGGCCTCGCCGAGCGCGTG
CTGGTGGTCGTCCCGGAGCACCTCGCGTTCCAGTGGCTGGCGGAGCTGTTCCACAAGTTCAACGCGCTGTTCGCGCTCCT
CACCCCGGAGCGGATCGAGGCGCTGGGCGGCCCGGAGGCGGCGCTCGCCCGCTCGCCGCACGCGATCGTCTCCTTCGAGG
CGCTCCGCGCCGACCCGGACCTGTCCGAGGCCGCGGCGGACCTGCCGCTCGACCTCGTGGTGGTGGACGAGGCCCACCAC
CTCGCCGAGGACGCGCTGCACGACCGGGTCGCGCCGATCTGCCGCGCCTCCTTCGGCGTGCTGCTGCTCACCGCCACGCC
GGTCCGCCTGGATCCGCGCGAGTACTTCCGCCTGCTCTCCCTGGTCGAGCCGGTCCCCTCCACCTCGCTCGACGACTTCC
TCGCCCGCCTGGAGCAGCACGAGGCCTACGCGCAGGTGGCCCGCGAGCTCCTCGCCGGCGGCGACCTCGCCGCGGCGGCG
GAGCGGCTGCGCGCGCTGGCGCCGGACGACCCGGTGTTCTCGAAGGCGCCGCCGGCGCTCGACCGCGCCGCGCTGCTCGC
GCACCTCGCCGAGCGCTACGGCCTGTCCGCCCGGCTCATCCGCAACCGCCGCGTGAAGGTGGGCGCGTTCACCTCCCGCG
TGCTCCGCCGCGTGGACGTGGGCGAGGGCGAGAAGCCGAAGGCGCTGGTGGACCTCTGCGCCGGGCTCGCGCGCGGGGGC
GAGAAGGTGCTCGTGTTCGGCGGCGACCTCGAGGCGCTGCGCGGGCTGCAGGGCGGGCTCGCCGAGGCGGGGCTGGAGGC
GCTGCTCTACGACGACGCGCCCTCGCTCGAGGCGCGCGACCGGCTGGTGGCCCGCTTCCGCGATCCGGAGGGCCCCATGT
TGCTGCTCTCCGGCGAGTCCGGCGGCGAGGGGCGCAACTTCCAGTTCGCGCACCACCTCGTGTGCGCCGACCTGCCGGCG
TCGCCGCTCGTGCTCGAGCAGCGCATCGGGCGGCTCGACCGGCTGGGCCAGACGCGGCCGGTCGAGATCCACGTGCCGGT
GGAGCCGGGCGACGAGGCGTTCCTGGCCGACCTGTACGAGAAGGAGATCGGCATCTTCGACGAGCCGGTGGGCGGCCTGG
ACGCGGTGCTGGCCTCGCTGCCGGAGGAGCTGGCGGCGCTGCAGCGCAAGCGCTCCGACCGCACCCGCGACGCGTTCCGG
AAGGACCTCGCGAAGCGCGTCGCCGCCGCCCGCAAGGCGCAGCACGAGGGCGATCCGCTCCTCGACATCCGCTCCGCGTC
GCTGCCCGAGCTGGGCCGCCTCGTACGCGGCGCGTTCGAGCGCATGGGCGAGGACGCGCCCGAGGGCATCGACGGCGGCG
ACGGAGCGGGGGCCGCGCTGGAGCAGTCGCTCATCACGCTCTCGCGCTGGCTGGAGGAGGAGCTGGAGGACGTCTGCGCC
GACGTGGGGCGCCGTGTCGGCATGGACGTGGACACCGACCAGAACGTCCAGCCGTTCGAGGTGTCGTTCACGCTCGGCTC
GGGCATGCGCATCGAGGCGCTGCCGGGGATGCAGATCCCCGACGAGCCGGAGACGTTCGTGGGGAGCTTCTGGCGCGAGA
CGGCGGTGGCCCGCGACGAGCTGCACTGGTACGCGACCGGCCACAAGCTGGTGGAGGCGCTGCTCGGGCTGGTGCGCGAC
GGCGACGCGGGGCGGAGCGCGGCGGTGAAGCGGGAGTGGGCGCCGCGCCGGGGCGGCCTGTACGCGCGCTTCGAGCCGCG
CCTCGCCACCGCCGCCGACGTGGCGCCGGGCGCGCGGGTCGCCTCGCGGCAGGCGTCGCGCTACCTCGACCTCTCGCCCA
TCGCGGTGGTGGTGGACCTGGAGGCGGGGAACCGGGTGCTGCCCGGCGCCGCGCACCGGCTCGAGGACGAGATCGACGAC
GTGCAGGACGCGCGGGTGGGCGCGCCGCCGCCGGCCGCGCTGGAGGCGGCCCGCGCGGCCGCGGAGCGCGAGGCGCGGCT
GGTGATGGAGCGGCGCCGCGAGGAGGCGGTGGGCCTGCTCCTCGCGCACGCCGACGCCGAGGAGGAGCGGCTCATCGAGG
CCGCGTTCGCGGGCGGCGCGCCGCGCGAGCGGATCGACGGGGCGCTGGCGGTGCTGCGCCACCACCGCGACGTGGTGGCG
AAGTCCATCGAGCGGGTGAAGCTCGACCTCGACGCGGCGGCGCTGATCGTGCCCTGA

Upstream 100 bases:

>100_bases
TCACGGGAGGGCCCGGACCGAACCAGCCGTCCGGTCGGGGGGATCGGTCGGGCGACGGTCTTGCTGGACCGGCCTGGGTG
CCGATGGTAAGGGGCGCGCG

Downstream 100 bases:

>100_bases
GGCGGGCGCGCCGCAGGGCGCCGTCACGCGCAGAAGCGCGCGATGGCGTTCCCGAGGATCGTCACCGCCCGCTCGACCTG
GTCGAGCGGCACCGACTCAC

Product: helicase domain-containing protein

Products: NA

Alternate protein names: ATP-dependent helicase hepA [H]

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MAWKAGMKVVHRAQRAWGVGVVVQVADEGRRLAVRFAGREGITVVSGRDQALVEVPADTPIEQVASGPIEALGSAQPATA
SAFALRTRVNRLEALRRADSLGALLSSRVHVLPHQVGAAGRILSDRMPRFVLADEVGLGKTVEAGLVFAGMRQLGLAERV
LVVVPEHLAFQWLAELFHKFNALFALLTPERIEALGGPEAALARSPHAIVSFEALRADPDLSEAAADLPLDLVVVDEAHH
LAEDALHDRVAPICRASFGVLLLTATPVRLDPREYFRLLSLVEPVPSTSLDDFLARLEQHEAYAQVARELLAGGDLAAAA
ERLRALAPDDPVFSKAPPALDRAALLAHLAERYGLSARLIRNRRVKVGAFTSRVLRRVDVGEGEKPKALVDLCAGLARGG
EKVLVFGGDLEALRGLQGGLAEAGLEALLYDDAPSLEARDRLVARFRDPEGPMLLLSGESGGEGRNFQFAHHLVCADLPA
SPLVLEQRIGRLDRLGQTRPVEIHVPVEPGDEAFLADLYEKEIGIFDEPVGGLDAVLASLPEELAALQRKRSDRTRDAFR
KDLAKRVAAARKAQHEGDPLLDIRSASLPELGRLVRGAFERMGEDAPEGIDGGDGAGAALEQSLITLSRWLEEELEDVCA
DVGRRVGMDVDTDQNVQPFEVSFTLGSGMRIEALPGMQIPDEPETFVGSFWRETAVARDELHWYATGHKLVEALLGLVRD
GDAGRSAAVKREWAPRRGGLYARFEPRLATAADVAPGARVASRQASRYLDLSPIAVVVDLEAGNRVLPGAAHRLEDEIDD
VQDARVGAPPPAALEAARAAAEREARLVMERRREEAVGLLLAHADAEEERLIEAAFAGGAPRERIDGALAVLRHHRDVVA
KSIERVKLDLDAAALIVP

Sequences:

>Translated_898_residues
MAWKAGMKVVHRAQRAWGVGVVVQVADEGRRLAVRFAGREGITVVSGRDQALVEVPADTPIEQVASGPIEALGSAQPATA
SAFALRTRVNRLEALRRADSLGALLSSRVHVLPHQVGAAGRILSDRMPRFVLADEVGLGKTVEAGLVFAGMRQLGLAERV
LVVVPEHLAFQWLAELFHKFNALFALLTPERIEALGGPEAALARSPHAIVSFEALRADPDLSEAAADLPLDLVVVDEAHH
LAEDALHDRVAPICRASFGVLLLTATPVRLDPREYFRLLSLVEPVPSTSLDDFLARLEQHEAYAQVARELLAGGDLAAAA
ERLRALAPDDPVFSKAPPALDRAALLAHLAERYGLSARLIRNRRVKVGAFTSRVLRRVDVGEGEKPKALVDLCAGLARGG
EKVLVFGGDLEALRGLQGGLAEAGLEALLYDDAPSLEARDRLVARFRDPEGPMLLLSGESGGEGRNFQFAHHLVCADLPA
SPLVLEQRIGRLDRLGQTRPVEIHVPVEPGDEAFLADLYEKEIGIFDEPVGGLDAVLASLPEELAALQRKRSDRTRDAFR
KDLAKRVAAARKAQHEGDPLLDIRSASLPELGRLVRGAFERMGEDAPEGIDGGDGAGAALEQSLITLSRWLEEELEDVCA
DVGRRVGMDVDTDQNVQPFEVSFTLGSGMRIEALPGMQIPDEPETFVGSFWRETAVARDELHWYATGHKLVEALLGLVRD
GDAGRSAAVKREWAPRRGGLYARFEPRLATAADVAPGARVASRQASRYLDLSPIAVVVDLEAGNRVLPGAAHRLEDEIDD
VQDARVGAPPPAALEAARAAAEREARLVMERRREEAVGLLLAHADAEEERLIEAAFAGGAPRERIDGALAVLRHHRDVVA
KSIERVKLDLDAAALIVP
>Mature_897_residues
AWKAGMKVVHRAQRAWGVGVVVQVADEGRRLAVRFAGREGITVVSGRDQALVEVPADTPIEQVASGPIEALGSAQPATAS
AFALRTRVNRLEALRRADSLGALLSSRVHVLPHQVGAAGRILSDRMPRFVLADEVGLGKTVEAGLVFAGMRQLGLAERVL
VVVPEHLAFQWLAELFHKFNALFALLTPERIEALGGPEAALARSPHAIVSFEALRADPDLSEAAADLPLDLVVVDEAHHL
AEDALHDRVAPICRASFGVLLLTATPVRLDPREYFRLLSLVEPVPSTSLDDFLARLEQHEAYAQVARELLAGGDLAAAAE
RLRALAPDDPVFSKAPPALDRAALLAHLAERYGLSARLIRNRRVKVGAFTSRVLRRVDVGEGEKPKALVDLCAGLARGGE
KVLVFGGDLEALRGLQGGLAEAGLEALLYDDAPSLEARDRLVARFRDPEGPMLLLSGESGGEGRNFQFAHHLVCADLPAS
PLVLEQRIGRLDRLGQTRPVEIHVPVEPGDEAFLADLYEKEIGIFDEPVGGLDAVLASLPEELAALQRKRSDRTRDAFRK
DLAKRVAAARKAQHEGDPLLDIRSASLPELGRLVRGAFERMGEDAPEGIDGGDGAGAALEQSLITLSRWLEEELEDVCAD
VGRRVGMDVDTDQNVQPFEVSFTLGSGMRIEALPGMQIPDEPETFVGSFWRETAVARDELHWYATGHKLVEALLGLVRDG
DAGRSAAVKREWAPRRGGLYARFEPRLATAADVAPGARVASRQASRYLDLSPIAVVVDLEAGNRVLPGAAHRLEDEIDDV
QDARVGAPPPAALEAARAAAEREARLVMERRREEAVGLLLAHADAEEERLIEAAFAGGAPRERIDGALAVLRHHRDVVAK
SIERVKLDLDAAALIVP

Specific function: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on

COG id: COG0553

COG function: function code KL; Superfamily II DNA/RNA helicases, SNF2 family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786245, Length=927, Percent_Identity=28.0474649406688, Blast_Score=213, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR022737
- InterPro:   IPR000330 [H]

Pfam domain/function: PF00271 Helicase_C; PF12137 RapA_C; PF00176 SNF2_N [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 96855; Mature: 96723

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWKAGMKVVHRAQRAWGVGVVVQVADEGRRLAVRFAGREGITVVSGRDQALVEVPADTP
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCEEEECCCCCC
IEQVASGPIEALGSAQPATASAFALRTRVNRLEALRRADSLGALLSSRVHVLPHQVGAAG
HHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHH
RILSDRMPRFVLADEVGLGKTVEAGLVFAGMRQLGLAERVLVVVPEHLAFQWLAELFHKF
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCHHHHHEEECCHHHHHHHHHHHHHHH
NALFALLTPERIEALGGPEAALARSPHAIVSFEALRADPDLSEAAADLPLDLVVVDEAHH
HHHHHHCCHHHHHHCCCCHHHHHCCCCHHEEHHHHCCCCCHHHHHHCCCEEEEEECCHHH
LAEDALHDRVAPICRASFGVLLLTATPVRLDPREYFRLLSLVEPVPSTSLDDFLARLEQH
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EAYAQVARELLAGGDLAAAAERLRALAPDDPVFSKAPPALDRAALLAHLAERYGLSARLI
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
RNRRVKVGAFTSRVLRRVDVGEGEKPKALVDLCAGLARGGEKVLVFGGDLEALRGLQGGL
HCCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCH
AEAGLEALLYDDAPSLEARDRLVARFRDPEGPMLLLSGESGGEGRNFQFAHHLVCADLPA
HHHCCHHEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCC
SPLVLEQRIGRLDRLGQTRPVEIHVPVEPGDEAFLADLYEKEIGIFDEPVGGLDAVLASL
CHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
PEELAALQRKRSDRTRDAFRKDLAKRVAAARKAQHEGDPLLDIRSASLPELGRLVRGAFE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHH
RMGEDAPEGIDGGDGAGAALEQSLITLSRWLEEELEDVCADVGRRVGMDVDTDQNVQPFE
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VSFTLGSGMRIEALPGMQIPDEPETFVGSFWRETAVARDELHWYATGHKLVEALLGLVRD
EEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCC
GDAGRSAAVKREWAPRRGGLYARFEPRLATAADVAPGARVASRQASRYLDLSPIAVVVDL
CCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEE
EAGNRVLPGAAHRLEDEIDDVQDARVGAPPPAALEAARAAAEREARLVMERRREEAVGLL
CCCCEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LAHADAEEERLIEAAFAGGAPRERIDGALAVLRHHRDVVAKSIERVKLDLDAAALIVP
EEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECC
>Mature Secondary Structure 
AWKAGMKVVHRAQRAWGVGVVVQVADEGRRLAVRFAGREGITVVSGRDQALVEVPADTP
CCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCEEEECCCCCC
IEQVASGPIEALGSAQPATASAFALRTRVNRLEALRRADSLGALLSSRVHVLPHQVGAAG
HHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHH
RILSDRMPRFVLADEVGLGKTVEAGLVFAGMRQLGLAERVLVVVPEHLAFQWLAELFHKF
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCHHHHHEEECCHHHHHHHHHHHHHHH
NALFALLTPERIEALGGPEAALARSPHAIVSFEALRADPDLSEAAADLPLDLVVVDEAHH
HHHHHHCCHHHHHHCCCCHHHHHCCCCHHEEHHHHCCCCCHHHHHHCCCEEEEEECCHHH
LAEDALHDRVAPICRASFGVLLLTATPVRLDPREYFRLLSLVEPVPSTSLDDFLARLEQH
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EAYAQVARELLAGGDLAAAAERLRALAPDDPVFSKAPPALDRAALLAHLAERYGLSARLI
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
RNRRVKVGAFTSRVLRRVDVGEGEKPKALVDLCAGLARGGEKVLVFGGDLEALRGLQGGL
HCCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCH
AEAGLEALLYDDAPSLEARDRLVARFRDPEGPMLLLSGESGGEGRNFQFAHHLVCADLPA
HHHCCHHEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCC
SPLVLEQRIGRLDRLGQTRPVEIHVPVEPGDEAFLADLYEKEIGIFDEPVGGLDAVLASL
CHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
PEELAALQRKRSDRTRDAFRKDLAKRVAAARKAQHEGDPLLDIRSASLPELGRLVRGAFE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHH
RMGEDAPEGIDGGDGAGAALEQSLITLSRWLEEELEDVCADVGRRVGMDVDTDQNVQPFE
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VSFTLGSGMRIEALPGMQIPDEPETFVGSFWRETAVARDELHWYATGHKLVEALLGLVRD
EEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCC
GDAGRSAAVKREWAPRRGGLYARFEPRLATAADVAPGARVASRQASRYLDLSPIAVVVDL
CCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEE
EAGNRVLPGAAHRLEDEIDDVQDARVGAPPPAALEAARAAAEREARLVMERRREEAVGLL
CCCCEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LAHADAEEERLIEAAFAGGAPRERIDGALAVLRHHRDVVAKSIERVKLDLDAAALIVP
EEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA