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The map label for this gene is adrA [H]

Identifier: 220915577

GI number: 220915577

Start: 525652

End: 526632

Strand: Reverse

Name: adrA [H]

Synonym: A2cp1_0458

Alternate gene names: 220915577

Gene position: 526632-525652 (Counterclockwise)

Preceding gene: 220915579

Following gene: 220915576

Centisome position: 10.47

GC content: 77.27

Gene sequence:

>981_bases
TTGCCGGTCGAGCGACGGAGCGAGCGCACCTGGACGACACTGCCGACCACGCCCTGCGCGGCGGGGCGGCGCCACGCCTT
CCTGCTCGTGCTGGCCGGCCCGCAGCTCGGGGACATCTACCCGCTGGCCTCGGACCGCGAGCTCGTCATCGGCCGGCGCG
ACGACTGCGACCTCCCCATCCACGACGACGGCGTGTCACGCCGCCACGCGGCCATCCGCGTCGAGGGCGAGGGCGCGCTG
CTGCGCGACCTGGGCAGCGCGAACGGCACCTACGTGGACGGCGCGCGCGCCGAGGGCGAGGTGCGGCTCGCCGACGGCGG
CCGGGTCAGCCTGGGCGGCGCGACCGTGCTGAAGTTCGCCTGGGCCGACGAGCTCGAGGCGCGCTGGCAGATGAAGCTCG
CCGAGATCGCGCTGCTCGACCCGCTCACCGGCGTGTTCAACCGGCGCCACCTCGACGACCGGCTCGCCGCCGAGCTCGCC
GCGGCGCAGCGGCACGGCCGGTCCATGTCGGTGCTGCTCGTGGACGTGGACCGGTTCCGGGCCGTGAACGAGGCGCACGG
CCAGGCCGCCGGCGACGAGGCGCTGAAGATGGTCGCGTTCGTGCTCCGCGGCGCGCTCCGGCGCGAGGACGTGCTCGCGC
GCGCCGGCGGCGCGGCGTTCGCGGTCATCGCCCGGGAGACGACGCTCGCGGGCGGCCGGGCGCTCGGCGAGCGCATCCGG
CGCGCGGTGGCGCGGAGCCGCTGCGCGTGGCAGCCGCAGGACGGCGGCGAGGCGGCCTCCATCGGCGTGAAGGTCTCGGT
GGGCGTGGCCGAGGTCGCCGAGGGGCGCACGCAGCGCGAGGTGATGGAGTCGGCCGGGCGGGCGCTCCAGCTCGCGAAGC
AGGCGGGCCGCAACACCGTGGTCGCGCTCCCGATGGCGCCAGCCGAGGGGCGGCCTGATCCGGCGCAAGCGGCCATGACG
CGCGGCGGCGCGGCGCCTTGA

Upstream 100 bases:

>100_bases
GGTCGCGTAACGCGAGGTGACCGCCCGTTCAACCCGCGGCCAAGGGACGCGGGCCGGAGACCCACGTGCGGGTAGAATCC
GCGGCGGCGCGGGAGGCCAC

Downstream 100 bases:

>100_bases
CGCTGGGGGGAGGGCCTGCGATCCTCGCGCCGTTCCGCTCCCCGGCGAGCCCGGCGGCGCCCGCGACGCGGCGCCGCCCG
ACGGCTCCGGGCGGCGGCGA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPVERRSERTWTTLPTTPCAAGRRHAFLLVLAGPQLGDIYPLASDRELVIGRRDDCDLPIHDDGVSRRHAAIRVEGEGAL
LRDLGSANGTYVDGARAEGEVRLADGGRVSLGGATVLKFAWADELEARWQMKLAEIALLDPLTGVFNRRHLDDRLAAELA
AAQRHGRSMSVLLVDVDRFRAVNEAHGQAAGDEALKMVAFVLRGALRREDVLARAGGAAFAVIARETTLAGGRALGERIR
RAVARSRCAWQPQDGGEAASIGVKVSVGVAEVAEGRTQREVMESAGRALQLAKQAGRNTVVALPMAPAEGRPDPAQAAMT
RGGAAP

Sequences:

>Translated_326_residues
MPVERRSERTWTTLPTTPCAAGRRHAFLLVLAGPQLGDIYPLASDRELVIGRRDDCDLPIHDDGVSRRHAAIRVEGEGAL
LRDLGSANGTYVDGARAEGEVRLADGGRVSLGGATVLKFAWADELEARWQMKLAEIALLDPLTGVFNRRHLDDRLAAELA
AAQRHGRSMSVLLVDVDRFRAVNEAHGQAAGDEALKMVAFVLRGALRREDVLARAGGAAFAVIARETTLAGGRALGERIR
RAVARSRCAWQPQDGGEAASIGVKVSVGVAEVAEGRTQREVMESAGRALQLAKQAGRNTVVALPMAPAEGRPDPAQAAMT
RGGAAP
>Mature_325_residues
PVERRSERTWTTLPTTPCAAGRRHAFLLVLAGPQLGDIYPLASDRELVIGRRDDCDLPIHDDGVSRRHAAIRVEGEGALL
RDLGSANGTYVDGARAEGEVRLADGGRVSLGGATVLKFAWADELEARWQMKLAEIALLDPLTGVFNRRHLDDRLAAELAA
AQRHGRSMSVLLVDVDRFRAVNEAHGQAAGDEALKMVAFVLRGALRREDVLARAGGAAFAVIARETTLAGGRALGERIRR
AVARSRCAWQPQDGGEAASIGVKVSVGVAEVAEGRTQREVMESAGRALQLAKQAGRNTVVALPMAPAEGRPDPAQAAMTR
GGAAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=190, Percent_Identity=34.2105263157895, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=34.3373493975904, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=31.4814814814815, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082007, Length=175, Percent_Identity=34.8571428571429, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=32.5966850828729, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=30.2197802197802, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788085, Length=169, Percent_Identity=28.4023668639053, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787541, Length=173, Percent_Identity=31.2138728323699, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=28.125, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=29.0909090909091, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=25.8064516129032, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 34691; Mature: 34560

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50006 FHA_DOMAIN ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVERRSERTWTTLPTTPCAAGRRHAFLLVLAGPQLGDIYPLASDRELVIGRRDDCDLPI
CCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCCCCEECCCCCCEEEEECCCCCCCCC
HDDGVSRRHAAIRVEGEGALLRDLGSANGTYVDGARAEGEVRLADGGRVSLGGATVLKFA
CCCCCCCCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCEEEEECCCEEEECCCEEEEEH
WADELEARWQMKLAEIALLDPLTGVFNRRHLDDRLAAELAAAQRHGRSMSVLLVDVDRFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
AVNEAHGQAAGDEALKMVAFVLRGALRREDVLARAGGAAFAVIARETTLAGGRALGERIR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHCCCHHHHHHHHH
RAVARSRCAWQPQDGGEAASIGVKVSVGVAEVAEGRTQREVMESAGRALQLAKQAGRNTV
HHHHHHHCCCCCCCCCCEEEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEE
VALPMAPAEGRPDPAQAAMTRGGAAP
EEEECCCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
PVERRSERTWTTLPTTPCAAGRRHAFLLVLAGPQLGDIYPLASDRELVIGRRDDCDLPI
CCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCCCCEECCCCCCEEEEECCCCCCCCC
HDDGVSRRHAAIRVEGEGALLRDLGSANGTYVDGARAEGEVRLADGGRVSLGGATVLKFA
CCCCCCCCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCEEEEECCCEEEECCCEEEEEH
WADELEARWQMKLAEIALLDPLTGVFNRRHLDDRLAAELAAAQRHGRSMSVLLVDVDRFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
AVNEAHGQAAGDEALKMVAFVLRGALRREDVLARAGGAAFAVIARETTLAGGRALGERIR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHCCCHHHHHHHHH
RAVARSRCAWQPQDGGEAASIGVKVSVGVAEVAEGRTQREVMESAGRALQLAKQAGRNTV
HHHHHHHCCCCCCCCCCEEEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEE
VALPMAPAEGRPDPAQAAMTRGGAAP
EEEECCCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]