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The map label for this gene is murA

Identifier: 220915513

GI number: 220915513

Start: 443269

End: 444537

Strand: Reverse

Name: murA

Synonym: A2cp1_0394

Alternate gene names: 220915513

Gene position: 444537-443269 (Counterclockwise)

Preceding gene: 220915514

Following gene: 220915512

Centisome position: 8.84

GC content: 74.78

Gene sequence:

>1269_bases
TTGGACAAGATCGTGATCGAGGGAGGCGTCCCGCTCCGCGGGAGCGTGGACGTCTCCGGCGCGAAGAACGCCGCGCTGCC
CGTCATCGCCGCCGCCCTGCTCGCCGAGGGCGAGCACGAGGTGCGCAACGTCCCGGACCTCGCGGACGTGCGCACCCTCG
GCAAGCTGCTCGGGCACATGGGCTGCGAGGTGGCGCGCGGCGAGGGCGACCGGCGCACGGTCCGGCTCCGCGTTCCCGCC
GCGGTGGCGCCCGAGGCGCCCTACGAGCTCGTGAAGACCATGCGCGCCTCGGTGCTGGTGCTCGGGCCGCTGCTCGCGCG
CCTCGGCCGGGCGCGCGTCTCGCTGCCCGGCGGCTGCGCCATCGGCGCCCGCCCCATCGACCAGCACCTGAAGGCGCTCA
CCGCGCTCGGCGCCGAGATCCGGCTCGAGCACGGCTACGTGAACGCCAGCGTGCCGCGCGGCCGGCTCCGCGGCACGGTG
TTCACGTTCGACGCCCAGACCGTCACCGGCACCGAGAACGTGATGATGGCGGCGGCGCTCGCCGACGGCGAGACGGTGCT
GCGCAACTGCGCGCGCGAGCCGGAGGTGAAGGACCTCGGCGACGCGCTGGTCGCGATGGGCGCGCTGGTCGAGGGCGCCG
GCACCGACGAGATCTGGATCGAGGGCGTCCCATCGCTCCGGCCGCTGTCGCACGCGGTCATCCCCGACCGCATCGAGGCC
GGCACGTTCCTGGTGGCGGGCGCGCTGCCCGGCAACGACGTGACCGTCCGCGGCTGCGTGGCGGCGCACCAGGAGGCGCT
CGTCGAGAAGCTCCGCGCGGTCGGCGCCGAGGTGACGAAGGTGGAGGGCGGCCTGCGGGTGGTGGGCGACGGCCGCCCGC
GGCCGGTGGACGTGCGGACCGCGCCGCACCCCGGGTTCCCCACCGACATGCAGGCGCAGCTCATGGTGCTGCTCTGCCTC
GCCGACGGGACCTCGCGCATCACCGAGACGGTGTTCGAGAACCGCTTCATGCACGTTCAGGAGCTGATCCGCCTCGGCGC
CCACGTCGAGGTGGACGGGCGCGTCGCCATGGTGAAGGGCGTCCCGGAGCTGTCCGGCGCGCCGGTGATGGCGTCCGACC
TGCGGGCCTCCGCCGCGCTGGTGCTGGCCGGCCTCGCGGCGAGCGGGACGACCGAGGTGCTGCGCGTGTACCATCTCGAC
CGCGGCTACGAGCGGATCGAGGAGAAGCTGGCGCCCCTCGGGGCGCGCATCCGGAGGGTGAGAGGCTGA

Upstream 100 bases:

>100_bases
GCCTGCCGGGCGCCGCGTAGAATCCGCGCCGCCGCTCGCATCCCGCTTGCACGCTGCACCGTCCGGGCGATCCCCTGCCC
TGACGCGAAGGAGCCATCGT

Downstream 100 bases:

>100_bases
TGCCGGGTACGAGCGAGCTCATCACGGTGGCGGTGCCGAAGGGGCGCCTCCTGCAGGAGTCCTCGGCGCTGTTCGAGCGG
GCGCTCGGCGTGTCGCCGCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDKIVIEGGVPLRGSVDVSGAKNAALPVIAAALLAEGEHEVRNVPDLADVRTLGKLLGHMGCEVARGEGDRRTVRLRVPA
AVAPEAPYELVKTMRASVLVLGPLLARLGRARVSLPGGCAIGARPIDQHLKALTALGAEIRLEHGYVNASVPRGRLRGTV
FTFDAQTVTGTENVMMAAALADGETVLRNCAREPEVKDLGDALVAMGALVEGAGTDEIWIEGVPSLRPLSHAVIPDRIEA
GTFLVAGALPGNDVTVRGCVAAHQEALVEKLRAVGAEVTKVEGGLRVVGDGRPRPVDVRTAPHPGFPTDMQAQLMVLLCL
ADGTSRITETVFENRFMHVQELIRLGAHVEVDGRVAMVKGVPELSGAPVMASDLRASAALVLAGLAASGTTEVLRVYHLD
RGYERIEEKLAPLGARIRRVRG

Sequences:

>Translated_422_residues
MDKIVIEGGVPLRGSVDVSGAKNAALPVIAAALLAEGEHEVRNVPDLADVRTLGKLLGHMGCEVARGEGDRRTVRLRVPA
AVAPEAPYELVKTMRASVLVLGPLLARLGRARVSLPGGCAIGARPIDQHLKALTALGAEIRLEHGYVNASVPRGRLRGTV
FTFDAQTVTGTENVMMAAALADGETVLRNCAREPEVKDLGDALVAMGALVEGAGTDEIWIEGVPSLRPLSHAVIPDRIEA
GTFLVAGALPGNDVTVRGCVAAHQEALVEKLRAVGAEVTKVEGGLRVVGDGRPRPVDVRTAPHPGFPTDMQAQLMVLLCL
ADGTSRITETVFENRFMHVQELIRLGAHVEVDGRVAMVKGVPELSGAPVMASDLRASAALVLAGLAASGTTEVLRVYHLD
RGYERIEEKLAPLGARIRRVRG
>Mature_422_residues
MDKIVIEGGVPLRGSVDVSGAKNAALPVIAAALLAEGEHEVRNVPDLADVRTLGKLLGHMGCEVARGEGDRRTVRLRVPA
AVAPEAPYELVKTMRASVLVLGPLLARLGRARVSLPGGCAIGARPIDQHLKALTALGAEIRLEHGYVNASVPRGRLRGTV
FTFDAQTVTGTENVMMAAALADGETVLRNCAREPEVKDLGDALVAMGALVEGAGTDEIWIEGVPSLRPLSHAVIPDRIEA
GTFLVAGALPGNDVTVRGCVAAHQEALVEKLRAVGAEVTKVEGGLRVVGDGRPRPVDVRTAPHPGFPTDMQAQLMVLLCL
ADGTSRITETVFENRFMHVQELIRLGAHVEVDGRVAMVKGVPELSGAPVMASDLRASAALVLAGLAASGTTEVLRVYHLD
RGYERIEEKLAPLGARIRRVRG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=426, Percent_Identity=53.2863849765258, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_ANAD2 (B8JAU0)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490817.1
- ProteinModelPortal:   B8JAU0
- SMR:   B8JAU0
- GeneID:   7299277
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0394
- HOGENOM:   HBG482701
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44493; Mature: 44493

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVIEGGVPLRGSVDVSGAKNAALPVIAAALLAEGEHEVRNVPDLADVRTLGKLLGHM
CCEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHC
GCEVARGEGDRRTVRLRVPAAVAPEAPYELVKTMRASVLVLGPLLARLGRARVSLPGGCA
CCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
IGARPIDQHLKALTALGAEIRLEHGYVNASVPRGRLRGTVFTFDAQTVTGTENVMMAAAL
CCCCCHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCEEEEEEECCEECCCCCEEEEEEC
ADGETVLRNCAREPEVKDLGDALVAMGALVEGAGTDEIWIEGVPSLRPLSHAVIPDRIEA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHCCCCCCCCC
GTFLVAGALPGNDVTVRGCVAAHQEALVEKLRAVGAEVTKVEGGLRVVGDGRPRPVDVRT
CCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEC
APHPGFPTDMQAQLMVLLCLADGTSRITETVFENRFMHVQELIRLGAHVEVDGRVAMVKG
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEC
VPELSGAPVMASDLRASAALVLAGLAASGTTEVLRVYHLDRGYERIEEKLAPLGARIRRV
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHC
RG
CC
>Mature Secondary Structure
MDKIVIEGGVPLRGSVDVSGAKNAALPVIAAALLAEGEHEVRNVPDLADVRTLGKLLGHM
CCEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHC
GCEVARGEGDRRTVRLRVPAAVAPEAPYELVKTMRASVLVLGPLLARLGRARVSLPGGCA
CCEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
IGARPIDQHLKALTALGAEIRLEHGYVNASVPRGRLRGTVFTFDAQTVTGTENVMMAAAL
CCCCCHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCEEEEEEECCEECCCCCEEEEEEC
ADGETVLRNCAREPEVKDLGDALVAMGALVEGAGTDEIWIEGVPSLRPLSHAVIPDRIEA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHCCCCCCCCC
GTFLVAGALPGNDVTVRGCVAAHQEALVEKLRAVGAEVTKVEGGLRVVGDGRPRPVDVRT
CCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEC
APHPGFPTDMQAQLMVLLCLADGTSRITETVFENRFMHVQELIRLGAHVEVDGRVAMVKG
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEC
VPELSGAPVMASDLRASAALVLAGLAASGTTEVLRVYHLDRGYERIEEKLAPLGARIRRV
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA