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The map label for this gene is zraR [H]

Identifier: 220915470

GI number: 220915470

Start: 393946

End: 395571

Strand: Reverse

Name: zraR [H]

Synonym: A2cp1_0349

Alternate gene names: 220915470

Gene position: 395571-393946 (Counterclockwise)

Preceding gene: 220915485

Following gene: 220915469

Centisome position: 7.87

GC content: 73.06

Gene sequence:

>1626_bases
ATGCGCATCGAGGACCTCGACCTGAGGGAGATCCTCTCGTTCGATCCCAGGGGCGGGGTGATCCGCTTCATGGGCCAGCG
CGTGGTGCTGTTCGACGCGGTGGCCCTCGGCCTGCTGCGCAAGGAGCTCACGAACGCGTTCGGGACGTTCGCGGCCCGCG
GCGTCCTGACGCGGTTCGGCTACGCCCACGGGTGGCGCGTGGGCGAGGCGCTCGAGCACGAGCACCCGGACCTCTGGAAG
GAGGGGAAGGCCGGCCCGTTCCTGCCGCCGCTGAAGGGCCAGTTCATCCTCGGGGAGAACGTCCGCACCGACGGCCTCGG
CGACGCGCCGCTGGTCGAGACGGTGTGGCACCGCTCCTACGAGGCCGAGCAGCACCTGCTGCACATCGGGCTCTCCGACG
AGCCGGTGTGCTGGACCTCGGCCGCCTTCGCGAGCGGCTACCTCTCGTACAAGGAGCGGCGCGAGGTCTACGTCATCGAG
GACCGCTGCGTCGGCAAGGGCGACTCCGAGTGCCACATCGCCGCGCGCTTCAAGGAGCGCTGGGGCCCGGAGCTGGAGCG
CCACCTGCCCTACTACCACATGGAGTCGATCGATCACGCGCTGCAGGAGGTGTCGAGCAAGCTGCGGCGCACCGAGCGTC
GCCTGCGCGAGCGCCAGGCGGAGCTGGAGCGGCTCGCGACCTGCTCCGACCAGGACACCGGCCTGGTCGCGCGCAGCGAG
GCGATGCGCCGGGTGCTGGAGCGCGCGCGCAGCGTGGCGCGCACCGGCTCGTCGGTGGTGGTGACGGGCGAGAGCGGCGT
GGGGAAGGAGGAGGTGGCGCGCCTCGTCCACCGCTCCTCGGAGCGCGCCGGCGGGCCGTTCGTGGCCGTGAACTGCGGCG
CGATCCCGGAGACGCTGCTCGAGCGCGAGCTGTTCGGCCACGTGAAGGGGGCGTTCACCGGCGCCGAGACGGACGCGGTG
GGCCTGTTCGAGGCCGCCGACGGCGGCACGCTGTTCCTGGACGAGGTGGGCGAGGTCTCGCCCGCGATGCAGGTGAAGCT
CCTGCGCGCGCTCCAGGAGCGCGAGGTCCGCCCCGTGGGAGACAGCCGCTCGCGCAAGGTGGACGTGCGGATCGTCGCGG
CGACGAACCGTGACCTCGCCGTCGAGGTGGCGTCCGGCCGCTTCCGCCAGGACCTCTTCTACCGGCTCAACGTCATCGAG
CTGCGCGTGCCGCCGCTGCGCGATCGGCCGGACGACGTGGTCCCGCTGGCGCGCTGTTTCCTCGCGAAGCTGTCCCGCAG
CGCGCACCGGCCGGTCACCGGGTTCACGGCGCAGGTGGCGGACCTGCTGGTGCGCTATCCGTGGCCCGGCAACGTGCGGG
AGCTGCAGAACGCGGTGGAGTACGCGGTGGCGCTGTCCGCCGGGAACCAGGTGGGCGTCGACGATCTGCCGGAGGCGCTG
CGCCACGCGCCCCCCGCCCCGGCGCGACCCGGCGTGATCCGGCCGCTGCACGAGGTGGAGCGCGAGCACGTGCTCGCGGC
GCTGCGCACCGCCGGGGGCAACAAGGTGGCGACCGCCGCGGGGCTCCACATCGGGCTCGCCACGCTGTACCGGAAGCTGA
AGGAGTACGGCGAGCCGGCGCCCTGA

Upstream 100 bases:

>100_bases
CCTGCAGTCCTGCGACCTCACGCCGCTTTTCCCTGGACGCGGCTGGGCGCATCACTCGTCCTGAGAAACGGACCTCCCGT
TTCGAGAAACCGGAGCGGCG

Downstream 100 bases:

>100_bases
GCCCCGCGCCCGGCCCGTCCGTGCCCGGGCGCGCGGCCGCGGGCGCGGTTACGTACCCCGGCGCGGCGAGGCCGCCCCTC
TGCGCGCGAGGTGCGCCGCG

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MRIEDLDLREILSFDPRGGVIRFMGQRVVLFDAVALGLLRKELTNAFGTFAARGVLTRFGYAHGWRVGEALEHEHPDLWK
EGKAGPFLPPLKGQFILGENVRTDGLGDAPLVETVWHRSYEAEQHLLHIGLSDEPVCWTSAAFASGYLSYKERREVYVIE
DRCVGKGDSECHIAARFKERWGPELERHLPYYHMESIDHALQEVSSKLRRTERRLRERQAELERLATCSDQDTGLVARSE
AMRRVLERARSVARTGSSVVVTGESGVGKEEVARLVHRSSERAGGPFVAVNCGAIPETLLERELFGHVKGAFTGAETDAV
GLFEAADGGTLFLDEVGEVSPAMQVKLLRALQEREVRPVGDSRSRKVDVRIVAATNRDLAVEVASGRFRQDLFYRLNVIE
LRVPPLRDRPDDVVPLARCFLAKLSRSAHRPVTGFTAQVADLLVRYPWPGNVRELQNAVEYAVALSAGNQVGVDDLPEAL
RHAPPAPARPGVIRPLHEVEREHVLAALRTAGGNKVATAAGLHIGLATLYRKLKEYGEPAP

Sequences:

>Translated_541_residues
MRIEDLDLREILSFDPRGGVIRFMGQRVVLFDAVALGLLRKELTNAFGTFAARGVLTRFGYAHGWRVGEALEHEHPDLWK
EGKAGPFLPPLKGQFILGENVRTDGLGDAPLVETVWHRSYEAEQHLLHIGLSDEPVCWTSAAFASGYLSYKERREVYVIE
DRCVGKGDSECHIAARFKERWGPELERHLPYYHMESIDHALQEVSSKLRRTERRLRERQAELERLATCSDQDTGLVARSE
AMRRVLERARSVARTGSSVVVTGESGVGKEEVARLVHRSSERAGGPFVAVNCGAIPETLLERELFGHVKGAFTGAETDAV
GLFEAADGGTLFLDEVGEVSPAMQVKLLRALQEREVRPVGDSRSRKVDVRIVAATNRDLAVEVASGRFRQDLFYRLNVIE
LRVPPLRDRPDDVVPLARCFLAKLSRSAHRPVTGFTAQVADLLVRYPWPGNVRELQNAVEYAVALSAGNQVGVDDLPEAL
RHAPPAPARPGVIRPLHEVEREHVLAALRTAGGNKVATAAGLHIGLATLYRKLKEYGEPAP
>Mature_541_residues
MRIEDLDLREILSFDPRGGVIRFMGQRVVLFDAVALGLLRKELTNAFGTFAARGVLTRFGYAHGWRVGEALEHEHPDLWK
EGKAGPFLPPLKGQFILGENVRTDGLGDAPLVETVWHRSYEAEQHLLHIGLSDEPVCWTSAAFASGYLSYKERREVYVIE
DRCVGKGDSECHIAARFKERWGPELERHLPYYHMESIDHALQEVSSKLRRTERRLRERQAELERLATCSDQDTGLVARSE
AMRRVLERARSVARTGSSVVVTGESGVGKEEVARLVHRSSERAGGPFVAVNCGAIPETLLERELFGHVKGAFTGAETDAV
GLFEAADGGTLFLDEVGEVSPAMQVKLLRALQEREVRPVGDSRSRKVDVRIVAATNRDLAVEVASGRFRQDLFYRLNVIE
LRVPPLRDRPDDVVPLARCFLAKLSRSAHRPVTGFTAQVADLLVRYPWPGNVRELQNAVEYAVALSAGNQVGVDDLPEAL
RHAPPAPARPGVIRPLHEVEREHVLAALRTAGGNKVATAAGLHIGLATLYRKLKEYGEPAP

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=300, Percent_Identity=52.3333333333333, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1788550, Length=315, Percent_Identity=46.984126984127, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI87082117, Length=290, Percent_Identity=45.1724137931035, Blast_Score=246, Evalue=4e-66,
Organism=Escherichia coli, GI1788905, Length=307, Percent_Identity=44.6254071661238, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=43.217665615142, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789087, Length=347, Percent_Identity=40.6340057636888, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=44.5482866043614, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=41.5151515151515, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787583, Length=351, Percent_Identity=37.037037037037, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786524, Length=354, Percent_Identity=38.7005649717514, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081872, Length=257, Percent_Identity=41.2451361867704, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=33.6666666666667, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1789828, Length=330, Percent_Identity=30.9090909090909, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59957; Mature: 59957

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEDLDLREILSFDPRGGVIRFMGQRVVLFDAVALGLLRKELTNAFGTFAARGVLTRFG
CCCCCCCHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YAHGWRVGEALEHEHPDLWKEGKAGPFLPPLKGQFILGENVRTDGLGDAPLVETVWHRSY
CHHCCCHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCH
EAEQHLLHIGLSDEPVCWTSAAFASGYLSYKERREVYVIEDRCVGKGDSECHIAARFKER
HCCHHEEEECCCCCCCEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
WGPELERHLPYYHMESIDHALQEVSSKLRRTERRLRERQAELERLATCSDQDTGLVARSE
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AMRRVLERARSVARTGSSVVVTGESGVGKEEVARLVHRSSERAGGPFVAVNCGAIPETLL
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHH
ERELFGHVKGAFTGAETDAVGLFEAADGGTLFLDEVGEVSPAMQVKLLRALQEREVRPVG
HHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
DSRSRKVDVRIVAATNRDLAVEVASGRFRQDLFYRLNVIELRVPPLRDRPDDVVPLARCF
CCCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHH
LAKLSRSAHRPVTGFTAQVADLLVRYPWPGNVRELQNAVEYAVALSAGNQVGVDDLPEAL
HHHHHHHCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RHAPPAPARPGVIRPLHEVEREHVLAALRTAGGNKVATAAGLHIGLATLYRKLKEYGEPA
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
P
C
>Mature Secondary Structure
MRIEDLDLREILSFDPRGGVIRFMGQRVVLFDAVALGLLRKELTNAFGTFAARGVLTRFG
CCCCCCCHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YAHGWRVGEALEHEHPDLWKEGKAGPFLPPLKGQFILGENVRTDGLGDAPLVETVWHRSY
CHHCCCHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCH
EAEQHLLHIGLSDEPVCWTSAAFASGYLSYKERREVYVIEDRCVGKGDSECHIAARFKER
HCCHHEEEECCCCCCCEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
WGPELERHLPYYHMESIDHALQEVSSKLRRTERRLRERQAELERLATCSDQDTGLVARSE
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AMRRVLERARSVARTGSSVVVTGESGVGKEEVARLVHRSSERAGGPFVAVNCGAIPETLL
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHH
ERELFGHVKGAFTGAETDAVGLFEAADGGTLFLDEVGEVSPAMQVKLLRALQEREVRPVG
HHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
DSRSRKVDVRIVAATNRDLAVEVASGRFRQDLFYRLNVIELRVPPLRDRPDDVVPLARCF
CCCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHH
LAKLSRSAHRPVTGFTAQVADLLVRYPWPGNVRELQNAVEYAVALSAGNQVGVDDLPEAL
HHHHHHHCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RHAPPAPARPGVIRPLHEVEREHVLAALRTAGGNKVATAAGLHIGLATLYRKLKEYGEPA
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]