Click here to switch to the map view.

The map label for this gene is msrB [H]

Identifier: 220915469

GI number: 220915469

Start: 393395

End: 393817

Strand: Reverse

Name: msrB [H]

Synonym: A2cp1_0348

Alternate gene names: 220915469

Gene position: 393817-393395 (Counterclockwise)

Preceding gene: 220915470

Following gene: 220915467

Centisome position: 7.83

GC content: 74.47

Gene sequence:

>423_bases
ATGGACAAGCTCATCCTCTCCGACGCCGAGTGGCGCGCGCGGCTCACGCCGGAGCAGTACCAGGTGCTGCGCGGCCACGG
CACCGAGCCGCCGGGCACCGGCTGCTTCCTGGGCACGCACGAGCCGGGGACGTACGTGTGCGCGGGCTGCGGGAACCCGC
TCTTCCGCTCGGGCGAGAAGTTCGAGTCGGGCACCGGCTGGCCTTCGTTCACCCGGCCGGTCTCGCCCGACGCGGTGGTG
GAGGTGCACGATCGCTCGTACGGCATGCGCCGCACCGAGGTGCGGTGCGCCCGCTGCGACGGCCACCTGGGCCACGTGTT
CCCCGACGGTCCGCCGCCCACCGGGCTGCGGTACTGCATGAACTCGGCGGCCATGCGGCACGTGGCCGAGGGCGCGCCGC
TCGATCCGCCCGGCGCGGGCTGA

Upstream 100 bases:

>100_bases
GCGCGCGGCCGCGGGCGCGGTTACGTACCCCGGCGCGGCGAGGCCGCCCCTCTGCGCGCGAGGTGCGCCGCGGAGGCGCC
CGAGGTGCCCCGAGGTCCCC

Downstream 100 bases:

>100_bases
AGAGCACGTGAACCCATCCCCTCCCGTCGCCGCGGCGGCCGATCCGCGTCGCATCGCGTCGTTGCTCCTCCCTCACATGC
CTCGGGGCATGCTCGGTCGT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MDKLILSDAEWRARLTPEQYQVLRGHGTEPPGTGCFLGTHEPGTYVCAGCGNPLFRSGEKFESGTGWPSFTRPVSPDAVV
EVHDRSYGMRRTEVRCARCDGHLGHVFPDGPPPTGLRYCMNSAAMRHVAEGAPLDPPGAG

Sequences:

>Translated_140_residues
MDKLILSDAEWRARLTPEQYQVLRGHGTEPPGTGCFLGTHEPGTYVCAGCGNPLFRSGEKFESGTGWPSFTRPVSPDAVV
EVHDRSYGMRRTEVRCARCDGHLGHVFPDGPPPTGLRYCMNSAAMRHVAEGAPLDPPGAG
>Mature_140_residues
MDKLILSDAEWRARLTPEQYQVLRGHGTEPPGTGCFLGTHEPGTYVCAGCGNPLFRSGEKFESGTGWPSFTRPVSPDAVV
EVHDRSYGMRRTEVRCARCDGHLGHVFPDGPPPTGLRYCMNSAAMRHVAEGAPLDPPGAG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=123, Percent_Identity=50.4065040650407, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI301336162, Length=123, Percent_Identity=50.4065040650407, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI73089054, Length=123, Percent_Identity=50.4065040650407, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI37620216, Length=123, Percent_Identity=50.4065040650407, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=48.8549618320611, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI7706511, Length=99, Percent_Identity=38.3838383838384, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788077, Length=120, Percent_Identity=52.5, Blast_Score=137, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553450, Length=122, Percent_Identity=53.2786885245902, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=122, Percent_Identity=53.2786885245902, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221378664, Length=142, Percent_Identity=46.4788732394366, Blast_Score=129, Evalue=6e-31,
Organism=Drosophila melanogaster, GI45553335, Length=140, Percent_Identity=48.5714285714286, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356369, Length=140, Percent_Identity=48.5714285714286, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24645799, Length=140, Percent_Identity=48.5714285714286, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI221378662, Length=149, Percent_Identity=43.6241610738255, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645801, Length=151, Percent_Identity=44.3708609271523, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24645804, Length=151, Percent_Identity=44.3708609271523, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15123; Mature: 15123

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLILSDAEWRARLTPEQYQVLRGHGTEPPGTGCFLGTHEPGTYVCAGCGNPLFRSGEK
CCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEECCCCHHHCCCCC
FESGTGWPSFTRPVSPDAVVEVHDRSYGMRRTEVRCARCDGHLGHVFPDGPPPTGLRYCM
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHEEEECCCCCCCCCCCCCCCCHHHHHHH
NSAAMRHVAEGAPLDPPGAG
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDKLILSDAEWRARLTPEQYQVLRGHGTEPPGTGCFLGTHEPGTYVCAGCGNPLFRSGEK
CCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEECCCCHHHCCCCC
FESGTGWPSFTRPVSPDAVVEVHDRSYGMRRTEVRCARCDGHLGHVFPDGPPPTGLRYCM
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHEEEECCCCCCCCCCCCCCCCHHHHHHH
NSAAMRHVAEGAPLDPPGAG
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]