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The map label for this gene is tkt [H]

Identifier: 220915432

GI number: 220915432

Start: 345512

End: 347509

Strand: Reverse

Name: tkt [H]

Synonym: A2cp1_0311

Alternate gene names: 220915432

Gene position: 347509-345512 (Counterclockwise)

Preceding gene: 220915433

Following gene: 220915428

Centisome position: 6.91

GC content: 74.12

Gene sequence:

>1998_bases
GTGCCGAACGCTCGCCCCGAGCTCGTCGAGAAGGCCGTGAACACCATCCGCATGCTCGCCGCCGACGGCGTGCAGCAGGC
GAACAGCGGCCACCCCGGCATGCCCATGGGCGCCGCGGACATGGCCTTCGTCCTCTGGACGCGCCACCTGCGCTTCGACC
CCGCGGAGCCGCGCTGGCTGGGCCGCGACCGGTTCCTCCTCTCGGCCGGCCACGGCTCGATGCTGCTGTACTCGCTGCTC
CACCTGGCGGGCTTCGACTGCGCGCTCGAGGACCTGAAGCACTTCCGCCAGCTCCACTCGCGCACGCCCGGGCACCCCGA
GTACGGCTTCCTGCCCGGCGTCGAGATCACGAGCGGCCCGCTCGGCCAGGGCTTCGCGAACGGCGTGGGCTTCGCGCTCG
GCCACGCCATGCTCGCGGCGAAGCTCGGGCCCGGCAACCCGGTCTCGGACGCGTTCGTCTACGCGATCGTCTCCGACGGC
GACCTGATGGAGGGCGTCTCGGCGGAGGCGGCCAGCTTCGCCGGCCACCACAAGCTCGGCCGGCTCGTCTACCTGTACGA
CGACAACGGCATCACCATCGACGGCAAGACCAGCATCACCTTCTCCGGCGAGGACGTGACCCGGCGCTTCGAGGCCTACG
GCTGGCACGTCCAGTCGGTGGACGGCCGCGACCACGACGGCATCGATCGCGCCCTCCAGGCGGCGAAGGCCGAGCTGGGC
CGCCCCAGCCTCATCCGCGTGCACACCACCATCGGCTTCGGCTCCCCCGCGAAGGCCGGCAAGTCGAGCGTGCACGGCGC
GCCGCTGGGCGAGGCGGAGCTCGAGGCCACCAAGAAGGCGCTGGGCTGGCCGCTCGAGCCGCGGTTCCTCGTCCCGGACG
ACGTCCGCGCCTACTGGGCCGAGGTCCGCGCCGAGAAGGCCGCGCAGAAGCAGGCCTGGCGCGCGGCCGAGCAGGCCTGG
CGCGCCGCCAACCCGGAGCAGGCGGCGCTGCTCGACGCGCACGTGGAGCGCTGGGTGCCGGAGCGGATCCTCGACCGCGC
CCGCGCCGAGCTGCCCGCGCCCGACGCGACCCGCAAGGTCTCGCAGGCCATCCTGCAGAAGATCGCGCCGCTCGTGCCCT
GCCTGGTGGGCGGGTCGGCCGACCTGGCCGAGTCGAACCTCACCGAGATCAAGGGCGCAGGCTCGGTGGCGCCGGGCAGC
TTCGCCGGCCGCAACCTCCACTTCGGCATCCGCGAGCACGCCATGGGGGCGATCGCGAACGGCCTCGCGTACGACGGCCT
GTTCGTCCCGTTCGTCGGCACGTTCCTGCAGTTCGCCGACTACATGCGCCCGCCGGTCCGGCTCGCCGCGCTCTCGAAGC
TCCAGGCCGTCTACGTGTGGACGCACGACTCGATCTTCCTGGGCGAGGACGGCCCCACGCACCAGCCCATCGAGCACCTC
ACCGCGCTGCGGGCCATCCCGAACCTGCACGTCTGCCGCCCGGCCGATCCGGAGGAGACCGCCGCCGCCTGGGCGCACGC
GCTGCAGCGCCGCGACGGTCCCACCGCGCTCGTCCTCACCCGCCAGAAGCTCGCGCCGGTGAAGCGCTCGGTGCCGCTCG
ATCCGGAGGCGATCCTCCGCGGCGGCTACCTGGTGGACGCGCCCGCGGGCGCCACGTTCACGCTCGTCGCCACCGGCTCG
GAGGTGCCGCTCGCGCAGGCCGCGCTCGAGGCGCTCGCGAAGCAGGGCGTGGTGGGCCGGCTCGCGTCGATCCCGTGCCT
GGAGTGCTTCCTCGCGCAGCCGAAGGCCTGGCGCGACGAGGTGGTGCCGCCCGGCCAGCGGGTGGCGGTGGTGGAGGCGG
CGCGCGGCACCGAGTGGTGGCAGCTCGCCGGCCGCGACGGCCTGGTGCTCGGGATCGAGCGCTTCGGCTCGAGCGCGCCG
GAGAAGGCGCTCGCCGAGGAGTACGGCTTCACGCCGGCGCAGGTCGCCGCGCGCGTGACGCGCTGGCTGGCGGGGTGA

Upstream 100 bases:

>100_bases
CGGGGCTGACGTCGCCGGCGCTCGGGCTGACGCCCCCCTTGATCTCGACGGTGCGGTGGGCGATGTTCCGCACCTCTTCC
CACCCCCGCGAGGAGTCCCC

Downstream 100 bases:

>100_bases
GCGCTGCAGGGGGGCTCGCGGGGCCGCGCCGCGGAGGCGGGCCGTCGTCGAGGCGTGAGGCGCGCCCGGCGGGCCGCCAC
GATGCGGCGGCCCGCCAGAC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MPNARPELVEKAVNTIRMLAADGVQQANSGHPGMPMGAADMAFVLWTRHLRFDPAEPRWLGRDRFLLSAGHGSMLLYSLL
HLAGFDCALEDLKHFRQLHSRTPGHPEYGFLPGVEITSGPLGQGFANGVGFALGHAMLAAKLGPGNPVSDAFVYAIVSDG
DLMEGVSAEAASFAGHHKLGRLVYLYDDNGITIDGKTSITFSGEDVTRRFEAYGWHVQSVDGRDHDGIDRALQAAKAELG
RPSLIRVHTTIGFGSPAKAGKSSVHGAPLGEAELEATKKALGWPLEPRFLVPDDVRAYWAEVRAEKAAQKQAWRAAEQAW
RAANPEQAALLDAHVERWVPERILDRARAELPAPDATRKVSQAILQKIAPLVPCLVGGSADLAESNLTEIKGAGSVAPGS
FAGRNLHFGIREHAMGAIANGLAYDGLFVPFVGTFLQFADYMRPPVRLAALSKLQAVYVWTHDSIFLGEDGPTHQPIEHL
TALRAIPNLHVCRPADPEETAAAWAHALQRRDGPTALVLTRQKLAPVKRSVPLDPEAILRGGYLVDAPAGATFTLVATGS
EVPLAQAALEALAKQGVVGRLASIPCLECFLAQPKAWRDEVVPPGQRVAVVEAARGTEWWQLAGRDGLVLGIERFGSSAP
EKALAEEYGFTPAQVAARVTRWLAG

Sequences:

>Translated_665_residues
MPNARPELVEKAVNTIRMLAADGVQQANSGHPGMPMGAADMAFVLWTRHLRFDPAEPRWLGRDRFLLSAGHGSMLLYSLL
HLAGFDCALEDLKHFRQLHSRTPGHPEYGFLPGVEITSGPLGQGFANGVGFALGHAMLAAKLGPGNPVSDAFVYAIVSDG
DLMEGVSAEAASFAGHHKLGRLVYLYDDNGITIDGKTSITFSGEDVTRRFEAYGWHVQSVDGRDHDGIDRALQAAKAELG
RPSLIRVHTTIGFGSPAKAGKSSVHGAPLGEAELEATKKALGWPLEPRFLVPDDVRAYWAEVRAEKAAQKQAWRAAEQAW
RAANPEQAALLDAHVERWVPERILDRARAELPAPDATRKVSQAILQKIAPLVPCLVGGSADLAESNLTEIKGAGSVAPGS
FAGRNLHFGIREHAMGAIANGLAYDGLFVPFVGTFLQFADYMRPPVRLAALSKLQAVYVWTHDSIFLGEDGPTHQPIEHL
TALRAIPNLHVCRPADPEETAAAWAHALQRRDGPTALVLTRQKLAPVKRSVPLDPEAILRGGYLVDAPAGATFTLVATGS
EVPLAQAALEALAKQGVVGRLASIPCLECFLAQPKAWRDEVVPPGQRVAVVEAARGTEWWQLAGRDGLVLGIERFGSSAP
EKALAEEYGFTPAQVAARVTRWLAG
>Mature_664_residues
PNARPELVEKAVNTIRMLAADGVQQANSGHPGMPMGAADMAFVLWTRHLRFDPAEPRWLGRDRFLLSAGHGSMLLYSLLH
LAGFDCALEDLKHFRQLHSRTPGHPEYGFLPGVEITSGPLGQGFANGVGFALGHAMLAAKLGPGNPVSDAFVYAIVSDGD
LMEGVSAEAASFAGHHKLGRLVYLYDDNGITIDGKTSITFSGEDVTRRFEAYGWHVQSVDGRDHDGIDRALQAAKAELGR
PSLIRVHTTIGFGSPAKAGKSSVHGAPLGEAELEATKKALGWPLEPRFLVPDDVRAYWAEVRAEKAAQKQAWRAAEQAWR
AANPEQAALLDAHVERWVPERILDRARAELPAPDATRKVSQAILQKIAPLVPCLVGGSADLAESNLTEIKGAGSVAPGSF
AGRNLHFGIREHAMGAIANGLAYDGLFVPFVGTFLQFADYMRPPVRLAALSKLQAVYVWTHDSIFLGEDGPTHQPIEHLT
ALRAIPNLHVCRPADPEETAAAWAHALQRRDGPTALVLTRQKLAPVKRSVPLDPEAILRGGYLVDAPAGATFTLVATGSE
VPLAQAALEALAKQGVVGRLASIPCLECFLAQPKAWRDEVVPPGQRVAVVEAARGTEWWQLAGRDGLVLGIERFGSSAPE
KALAEEYGFTPAQVAARVTRWLAG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=490, Percent_Identity=26.734693877551, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI4507521, Length=490, Percent_Identity=26.734693877551, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI133778974, Length=578, Percent_Identity=23.7024221453287, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI225637459, Length=589, Percent_Identity=21.2224108658744, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI225637461, Length=499, Percent_Identity=22.2444889779559, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI225637463, Length=499, Percent_Identity=22.2444889779559, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI48994911, Length=672, Percent_Identity=46.875, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1788808, Length=662, Percent_Identity=46.9788519637462, Blast_Score=562, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17539652, Length=675, Percent_Identity=25.7777777777778, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6325331, Length=669, Percent_Identity=44.2451420029895, Blast_Score=521, Evalue=1e-148,
Organism=Saccharomyces cerevisiae, GI6319593, Length=665, Percent_Identity=42.7067669172932, Blast_Score=498, Evalue=1e-141,
Organism=Drosophila melanogaster, GI45551847, Length=496, Percent_Identity=26.6129032258064, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45550715, Length=496, Percent_Identity=26.6129032258064, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24645119, Length=468, Percent_Identity=26.7094017094017, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666278, Length=492, Percent_Identity=25, Blast_Score=129, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71417; Mature: 71286

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNARPELVEKAVNTIRMLAADGVQQANSGHPGMPMGAADMAFVLWTRHLRFDPAEPRWL
CCCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GRDRFLLSAGHGSMLLYSLLHLAGFDCALEDLKHFRQLHSRTPGHPEYGFLPGVEITSGP
CCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LGQGFANGVGFALGHAMLAAKLGPGNPVSDAFVYAIVSDGDLMEGVSAEAASFAGHHKLG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHCCCHHHHHHHCHHCCC
RLVYLYDDNGITIDGKTSITFSGEDVTRRFEAYGWHVQSVDGRDHDGIDRALQAAKAELG
CEEEEECCCCEEECCCEEEEECCHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCC
RPSLIRVHTTIGFGSPAKAGKSSVHGAPLGEAELEATKKALGWPLEPRFLVPDDVRAYWA
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCHHHHHHHH
EVRAEKAAQKQAWRAAEQAWRAANPEQAALLDAHVERWVPERILDRARAELPAPDATRKV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SQAILQKIAPLVPCLVGGSADLAESNLTEIKGAGSVAPGSFAGRNLHFGIREHAMGAIAN
HHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHC
GLAYDGLFVPFVGTFLQFADYMRPPVRLAALSKLQAVYVWTHDSIFLGEDGPTHQPIEHL
CHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEEEEECCEEEECCCCCCCCHHHHH
TALRAIPNLHVCRPADPEETAAAWAHALQRRDGPTALVLTRQKLAPVKRSVPLDPEAILR
HHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCHHHHHC
GGYLVDAPAGATFTLVATGSEVPLAQAALEALAKQGVVGRLASIPCLECFLAQPKAWRDE
CCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCHHHHHHHCCCCCHHHC
VVPPGQRVAVVEAARGTEWWQLAGRDGLVLGIERFGSSAPEKALAEEYGFTPAQVAARVT
CCCCCCEEEEEEECCCCHHHEECCCCCEEEEHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
RWLAG
HHHCC
>Mature Secondary Structure 
PNARPELVEKAVNTIRMLAADGVQQANSGHPGMPMGAADMAFVLWTRHLRFDPAEPRWL
CCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GRDRFLLSAGHGSMLLYSLLHLAGFDCALEDLKHFRQLHSRTPGHPEYGFLPGVEITSGP
CCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LGQGFANGVGFALGHAMLAAKLGPGNPVSDAFVYAIVSDGDLMEGVSAEAASFAGHHKLG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHCCCHHHHHHHCHHCCC
RLVYLYDDNGITIDGKTSITFSGEDVTRRFEAYGWHVQSVDGRDHDGIDRALQAAKAELG
CEEEEECCCCEEECCCEEEEECCHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCC
RPSLIRVHTTIGFGSPAKAGKSSVHGAPLGEAELEATKKALGWPLEPRFLVPDDVRAYWA
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCHHHHHHHH
EVRAEKAAQKQAWRAAEQAWRAANPEQAALLDAHVERWVPERILDRARAELPAPDATRKV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SQAILQKIAPLVPCLVGGSADLAESNLTEIKGAGSVAPGSFAGRNLHFGIREHAMGAIAN
HHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHC
GLAYDGLFVPFVGTFLQFADYMRPPVRLAALSKLQAVYVWTHDSIFLGEDGPTHQPIEHL
CHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEEEEECCEEEECCCCCCCCHHHHH
TALRAIPNLHVCRPADPEETAAAWAHALQRRDGPTALVLTRQKLAPVKRSVPLDPEAILR
HHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCHHHHHC
GGYLVDAPAGATFTLVATGSEVPLAQAALEALAKQGVVGRLASIPCLECFLAQPKAWRDE
CCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCHHHHHHHCCCCCHHHC
VVPPGQRVAVVEAARGTEWWQLAGRDGLVLGIERFGSSAPEKALAEEYGFTPAQVAARVT
CCCCCCEEEEEEECCCCHHHEECCCCCEEEEHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
RWLAG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]