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The map label for this gene is fumA [H]

Identifier: 220915407

GI number: 220915407

Start: 320247

End: 320822

Strand: Reverse

Name: fumA [H]

Synonym: A2cp1_0286

Alternate gene names: 220915407

Gene position: 320822-320247 (Counterclockwise)

Preceding gene: 220915409

Following gene: 220915405

Centisome position: 6.38

GC content: 78.99

Gene sequence:

>576_bases
ATGCCGAAGACGCTCACGCTGCCGGCCCTGCCGGAGGACGTGCGCGGGCTCGCCGCGGGCGACGAGGTGCTGCTCCGCGG
CCGGATCGTCACCGGGCGCGAGGCGGCGCACCGCTACCTCGCGACGCACGACGACCCGCAGGTGCGGCGCTGGACCGAGG
GCGCCGTCCTCTACCACTGCGGCCCGGTGGTCGCGCGCGCGCCGGGCGGCGGCTGGCGCTTCGTGGCGGCCGGGCCGAGC
GCGTCGGGGCGCCAGGAGCCGTGGGAGGCGGAGGTGATCGCGCGCTACGGGCTGCGGGGCGTGCTCGGGAAGGGCGGCAT
GGGCCCGCGCACGCTCGAGGCGCTCCGCGCGCACGGCGCGGTGTACCTGCACGCGGCGGGCGGCCTGGCGGTGTCGCTGG
CGCGCCACGTGACCCGGGTGCTGGACGTGGCGCGGCTCGACGCGCTGGGCGTCACCGAGGCCATCTGGCTGGCCGAGGTG
GACGACTTCCCGGCGGTGGTGACCATGGACGCGCACGGGGAGACGCTGCACGCGCCCGGCGCGGAGGCGCCGGAGACGAC
GCCCGCGCCCGGCTAG

Upstream 100 bases:

>100_bases
TACCGCCCCGCCGCGCCGGACGGCAAGGGCCTGGCGCGCCGCCGGCCGTTATGGAAGCCGCCCCGGCCCGGACGTCGGAC
CGACCGTGAAGGGAGCCCGG

Downstream 100 bases:

>100_bases
GCGGCCGACGGACCGCGGCGGCGCGCGCCGGAGCGCATGCGCACCAGCCCGTAGAAGAGCTGCTTCTCGGTGTAGAGCCG
GCGCCCGGAGTACTCGCCGT

Product: Fe-S type hydro-lyase tartrate/fumarate beta subunit

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MPKTLTLPALPEDVRGLAAGDEVLLRGRIVTGREAAHRYLATHDDPQVRRWTEGAVLYHCGPVVARAPGGGWRFVAAGPS
ASGRQEPWEAEVIARYGLRGVLGKGGMGPRTLEALRAHGAVYLHAAGGLAVSLARHVTRVLDVARLDALGVTEAIWLAEV
DDFPAVVTMDAHGETLHAPGAEAPETTPAPG

Sequences:

>Translated_191_residues
MPKTLTLPALPEDVRGLAAGDEVLLRGRIVTGREAAHRYLATHDDPQVRRWTEGAVLYHCGPVVARAPGGGWRFVAAGPS
ASGRQEPWEAEVIARYGLRGVLGKGGMGPRTLEALRAHGAVYLHAAGGLAVSLARHVTRVLDVARLDALGVTEAIWLAEV
DDFPAVVTMDAHGETLHAPGAEAPETTPAPG
>Mature_190_residues
PKTLTLPALPEDVRGLAAGDEVLLRGRIVTGREAAHRYLATHDDPQVRRWTEGAVLYHCGPVVARAPGGGWRFVAAGPSA
SGRQEPWEAEVIARYGLRGVLGKGGMGPRTLEALRAHGAVYLHAAGGLAVSLARHVTRVLDVARLDALGVTEAIWLAEVD
DFPAVVTMDAHGETLHAPGAEAPETTPAPG

Specific function: Unknown

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789443, Length=183, Percent_Identity=36.0655737704918, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787897, Length=157, Percent_Identity=32.484076433121, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790564, Length=154, Percent_Identity=31.1688311688312, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646
- InterPro:   IPR004647
- InterPro:   IPR011167 [H]

Pfam domain/function: PF05681 Fumerase; PF05683 Fumerase_C [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 20079; Mature: 19948

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTLTLPALPEDVRGLAAGDEVLLRGRIVTGREAAHRYLATHDDPQVRRWTEGAVLYHC
CCCCEECCCCCHHHHCCCCCCEEEEEEEEEECHHHHHHHHCCCCCHHHEEECCCEEEEEC
GPVVARAPGGGWRFVAAGPSASGRQEPWEAEVIARYGLRGVLGKGGMGPRTLEALRAHGA
CCEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEECCCCCCCHHHHHHHHHCCE
VYLHAAGGLAVSLARHVTRVLDVARLDALGVTEAIWLAEVDDFPAVVTMDAHGETLHAPG
EEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCEEEEECCCCCEEECCC
AEAPETTPAPG
CCCCCCCCCCC
>Mature Secondary Structure 
PKTLTLPALPEDVRGLAAGDEVLLRGRIVTGREAAHRYLATHDDPQVRRWTEGAVLYHC
CCCEECCCCCHHHHCCCCCCEEEEEEEEEECHHHHHHHHCCCCCHHHEEECCCEEEEEC
GPVVARAPGGGWRFVAAGPSASGRQEPWEAEVIARYGLRGVLGKGGMGPRTLEALRAHGA
CCEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEECCCCCCCHHHHHHHHHCCE
VYLHAAGGLAVSLARHVTRVLDVARLDALGVTEAIWLAEVDDFPAVVTMDAHGETLHAPG
EEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCEEEEECCCCCEEECCC
AEAPETTPAPG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8473853 [H]