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The map label for this gene is ribB

Identifier: 220905551

GI number: 220905551

Start: 2759016

End: 2759687

Strand: Reverse

Name: ribB

Synonym: Ddes_2290

Alternate gene names: 220905551

Gene position: 2759687-2759016 (Counterclockwise)

Preceding gene: 220905553

Following gene: 220905546

Centisome position: 96.04

GC content: 61.31

Gene sequence:

>672_bases
ATGCATCAGTCCTCACTTTCCCTTGATTTCTTTGGCAGCCCGCACGAGCGGGTACAGAAGGCTCTGGCGTCCCTGCGCGC
CGGAGGCGGCGTTCTGGTGGTCGACGACGAAGACCGCGAAAATGAAGGTGACCTCATTTTTCCGGCCCAGACCATCACTG
TACCGCAAATGGCCATGCTCATAAGGCATTGCAGCGGTATTGTCTGCCTGTGCCTTACAGACGAGTACACCCGCCGCCTT
GATCTGCCAATGATGACAGAGCGTAATACCAATACCCAGCAGACGGCCTTCACCATTTCCATCGAGGCAGCCACAGGCGT
GACCACAGGAGTTTCCGCCGCTGACCGCGTGGCTACCATCCAGGCAGCCGTGGCGGAAAACGCCAGCCCCGAGAATTTAC
GCCGTCCGGGTCACGTGTTTCCCCTGCGGGCAAAGCCCGGTGGGGTGCTGGAGCGGCGCGGGCATACAGAGGCCACGGTT
GACCTCATGCGTCTGGCCGGGCATGCACCCTGCGGCGTACTGTGCGAACTGACCCTGGATGATGGAAGCATGGCCCGCCT
GCCGCAGGTGGCGGCCTTTGCTGTGGCTCATGCCATTCCCCTGTGCAGTGTGGAAGACCTGGTGGCCTGGCGGCATGGCC
TTGGGGAGGAAAACATCGCCATTTCTGCGTAG

Upstream 100 bases:

>100_bases
CTTTTGCCTTCGGGCTGAAGTTTCCGGTGGCATCCCTTTGAGCGGCCCGTCCACGCCCTGATGCACCCTCTCCCGGCACC
AGCCGGAAAAGGAGAACGGC

Downstream 100 bases:

>100_bases
ATAGCGGGCAAGCAGCTCCCGGAAATATGATACCGGACGGAAAGCTGTATCTCTGCATACATGATAAACAGGCCGTCCGC
ATTATGCGGACGGCCTGAAA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MHQSSLSLDFFGSPHERVQKALASLRAGGGVLVVDDEDRENEGDLIFPAQTITVPQMAMLIRHCSGIVCLCLTDEYTRRL
DLPMMTERNTNTQQTAFTISIEAATGVTTGVSAADRVATIQAAVAENASPENLRRPGHVFPLRAKPGGVLERRGHTEATV
DLMRLAGHAPCGVLCELTLDDGSMARLPQVAAFAVAHAIPLCSVEDLVAWRHGLGEENIAISA

Sequences:

>Translated_223_residues
MHQSSLSLDFFGSPHERVQKALASLRAGGGVLVVDDEDRENEGDLIFPAQTITVPQMAMLIRHCSGIVCLCLTDEYTRRL
DLPMMTERNTNTQQTAFTISIEAATGVTTGVSAADRVATIQAAVAENASPENLRRPGHVFPLRAKPGGVLERRGHTEATV
DLMRLAGHAPCGVLCELTLDDGSMARLPQVAAFAVAHAIPLCSVEDLVAWRHGLGEENIAISA
>Mature_223_residues
MHQSSLSLDFFGSPHERVQKALASLRAGGGVLVVDDEDRENEGDLIFPAQTITVPQMAMLIRHCSGIVCLCLTDEYTRRL
DLPMMTERNTNTQQTAFTISIEAATGVTTGVSAADRVATIQAAVAENASPENLRRPGHVFPLRAKPGGVLERRGHTEATV
DLMRLAGHAPCGVLCELTLDDGSMARLPQVAAFAVAHAIPLCSVEDLVAWRHGLGEENIAISA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=212, Percent_Identity=64.1509433962264, Blast_Score=283, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=44.7761194029851, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_DESDA (B8J4Q5)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480863.1
- GeneID:   7286008
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_2290
- HOGENOM:   HBG735778
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 23878; Mature: 23878

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: BINDING 44-44 BINDING 176-176

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQSSLSLDFFGSPHERVQKALASLRAGGGVLVVDDEDRENEGDLIFPAQTITVPQMAML
CCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCHHCCHHHHHHH
IRHCSGIVCLCLTDEYTRRLDLPMMTERNTNTQQTAFTISIEAATGVTTGVSAADRVATI
HHHCCCEEEEEECCHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHH
QAAVAENASPENLRRPGHVFPLRAKPGGVLERRGHTEATVDLMRLAGHAPCGVLCELTLD
HHHHHCCCCHHHHCCCCCEEEEECCCCCCHHCCCCCHHHHHHHHHHCCCCCCEEEEEEEC
DGSMARLPQVAAFAVAHAIPLCSVEDLVAWRHGLGEENIAISA
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MHQSSLSLDFFGSPHERVQKALASLRAGGGVLVVDDEDRENEGDLIFPAQTITVPQMAML
CCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCHHCCHHHHHHH
IRHCSGIVCLCLTDEYTRRLDLPMMTERNTNTQQTAFTISIEAATGVTTGVSAADRVATI
HHHCCCEEEEEECCHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHH
QAAVAENASPENLRRPGHVFPLRAKPGGVLERRGHTEATVDLMRLAGHAPCGVLCELTLD
HHHHHCCCCHHHHCCCCCEEEEECCCCCCHHCCCCCHHHHHHHHHHCCCCCCEEEEEEEC
DGSMARLPQVAAFAVAHAIPLCSVEDLVAWRHGLGEENIAISA
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA