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The map label for this gene is ompR [H]

Identifier: 220905533

GI number: 220905533

Start: 2735324

End: 2736046

Strand: Reverse

Name: ompR [H]

Synonym: Ddes_2272

Alternate gene names: 220905533

Gene position: 2736046-2735324 (Counterclockwise)

Preceding gene: 220905541

Following gene: 220905532

Centisome position: 95.22

GC content: 60.3

Gene sequence:

>723_bases
ATGGAACGCCGACAGACCATATGTCTTGTGGATGACGACCGGGAAATCCTGGACCTTTTGTCCGGCTATCTGAAGAAGCA
CGGCTTTGAGGTAAGCTGCGCCGAAAACGGTGATGCGCTTATGGATATTCTGCGCCGTGACAGGCCGGATCTTATAGTGC
TGGATGTCATGCTGCCCGGGCAGGACGGCTTTATGGTCTGCCGTGAGGTGCGGAAGCAGTGGCGCATCCCCATTATCTTT
CTGAGCGCGCTGGGTGAAAGCACAGACCGCGTGGTGGGGCTGGAGCTGGGCGCGGACGACTACATGGCCAAGCCCTTTGA
ACCGCGCGAGCTGCTGGCGCGCATCCGCAGCGTGCTGCGGCGTAACGAGGGTCTGCCTGTGCCGGCCAGAGAAAGCGGCA
GCATGCATTTTTCAGGCTGGCGTCTGGACAGGGCGTCCCGCTGTCTGCAATCTCCCTGTGGGGTTATGGTGAACCTGAGC
GGCGCCGAGTATCGCCTGCTCATGGCTTTTCTTGAAAACCCGCAAACAGTGCTGAGCCGCGACGCCCTTATGGACCTGAC
CCAGGGCCGCAATGCCGGGGCGTTTGACAGAAGCATAGACGTGCAGGTGAGCCGTCTGCGTACCCGCCTGCATGACAAGG
GCGGTGAAAAGACTGCGCTCATAAAGACTGTGCGCGGCGACGGCTATATCTGGACGGCGGATGTGCGCCGGGAAAACGCA
TGA

Upstream 100 bases:

>100_bases
GCGCTGACGAGCGGGCCACGCCATTGAAAGTTCCCGGCCGCGGGCTTACTGTACCCTCGGGTACGCCCGAAAACATGCGG
AACAGACATGCAGGGGAAAT

Downstream 100 bases:

>100_bases
ATACCGACCGCCATCTGCCCCAAAGCCTGTTTTCACGGTTGAGCCTTTTTTTGCTCGGGGCTTTTTTTATCCTGCACACC
GTGACCATCCTGACCGTGGC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MERRQTICLVDDDREILDLLSGYLKKHGFEVSCAENGDALMDILRRDRPDLIVLDVMLPGQDGFMVCREVRKQWRIPIIF
LSALGESTDRVVGLELGADDYMAKPFEPRELLARIRSVLRRNEGLPVPARESGSMHFSGWRLDRASRCLQSPCGVMVNLS
GAEYRLLMAFLENPQTVLSRDALMDLTQGRNAGAFDRSIDVQVSRLRTRLHDKGGEKTALIKTVRGDGYIWTADVRRENA

Sequences:

>Translated_240_residues
MERRQTICLVDDDREILDLLSGYLKKHGFEVSCAENGDALMDILRRDRPDLIVLDVMLPGQDGFMVCREVRKQWRIPIIF
LSALGESTDRVVGLELGADDYMAKPFEPRELLARIRSVLRRNEGLPVPARESGSMHFSGWRLDRASRCLQSPCGVMVNLS
GAEYRLLMAFLENPQTVLSRDALMDLTQGRNAGAFDRSIDVQVSRLRTRLHDKGGEKTALIKTVRGDGYIWTADVRRENA
>Mature_240_residues
MERRQTICLVDDDREILDLLSGYLKKHGFEVSCAENGDALMDILRRDRPDLIVLDVMLPGQDGFMVCREVRKQWRIPIIF
LSALGESTDRVVGLELGADDYMAKPFEPRELLARIRSVLRRNEGLPVPARESGSMHFSGWRLDRASRCLQSPCGVMVNLS
GAEYRLLMAFLENPQTVLSRDALMDLTQGRNAGAFDRSIDVQVSRLRTRLHDKGGEKTALIKTVRGDGYIWTADVRRENA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=43.8818565400844, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=36.864406779661, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.051724137931, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=36.7521367521368, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=36.4035087719298, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=34.4827586206897, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.695652173913, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.5555555555556, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=31.7180616740088, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=29.5652173913043, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=32.5892857142857, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=29.2576419213974, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=34.9056603773585, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27178; Mature: 27178

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRQTICLVDDDREILDLLSGYLKKHGFEVSCAENGDALMDILRRDRPDLIVLDVMLPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEEEECC
QDGFMVCREVRKQWRIPIIFLSALGESTDRVVGLELGADDYMAKPFEPRELLARIRSVLR
CCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RNEGLPVPARESGSMHFSGWRLDRASRCLQSPCGVMVNLSGAEYRLLMAFLENPQTVLSR
HCCCCCCCCCCCCCEEECCEEHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCHHHHHH
DALMDLTQGRNAGAFDRSIDVQVSRLRTRLHDKGGEKTALIKTVRGDGYIWTADVRRENA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCC
>Mature Secondary Structure
MERRQTICLVDDDREILDLLSGYLKKHGFEVSCAENGDALMDILRRDRPDLIVLDVMLPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEEEECC
QDGFMVCREVRKQWRIPIIFLSALGESTDRVVGLELGADDYMAKPFEPRELLARIRSVLR
CCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RNEGLPVPARESGSMHFSGWRLDRASRCLQSPCGVMVNLSGAEYRLLMAFLENPQTVLSR
HCCCCCCCCCCCCCEEECCEEHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCHHHHHH
DALMDLTQGRNAGAFDRSIDVQVSRLRTRLHDKGGEKTALIKTVRGDGYIWTADVRRENA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]