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The map label for this gene is cobB [H]

Identifier: 220905524

GI number: 220905524

Start: 2722456

End: 2724243

Strand: Reverse

Name: cobB [H]

Synonym: Ddes_2263

Alternate gene names: 220905524

Gene position: 2724243-2722456 (Counterclockwise)

Preceding gene: 220905525

Following gene: 220905523

Centisome position: 94.81

GC content: 63.03

Gene sequence:

>1788_bases
ATGCGAAACGCCATGAGCCATACCTGCCATATTTCTGAAGGCCGCAACTCGCGGTCCGTCCCGGAGTCCATGCCCCGCCT
TTGCGTTACAGCTCTTTCCGGCGGCGGCGGCAAGACGTTGCTTTCTTTGGGTATTTGCCGCGCATTTGTCCGGTCCGGCC
TTGTTGTGCAGCCTTTCAAGAAGGGGCCGGACTATATCGATGCCGCCTGGCTGCGCCTGGCCGCCGGGCGGCCCGCCGCC
AATCTTGACCCGTATTTTCTTGAGGCGCCGCGCCTGCGCGCTCTTTTTGTCCACGCCATGCGAAGCGCGGCCGCCCAACG
TGTGGAAGACATCGCGACAGGCGGGCAACCCGCTGCTGCGGGCAGGCGCCTGCTTGGCCTTGTGGAAGGTAACCGGGGTT
TTTTTGACGGCATGGACGCACGTGGCTCGTGCTCTACAGCGGAGCTTTCCCGTGTGCTGGCATGCCCGGTGGTCATCAGC
GTCGACTGTACCAAGATGACCCGCACAGCGGCGGCCCTGGTGCGCGGCATGCTGTATTTTGAGACGGGGATACGCTTTGC
GGGCGTGGTGCTCAATCAGGTCGGCTCCAGCCGGCATGAGCGCATTCTCAGGCAGGCGCTGGAGGAGCATACGGATGTTC
CCGTGCTTGGAGCCTTACCGCGGCTTGCGGAAAATCCGCTGCCTGAACGCCATATGGGCATTGCCTCCTGCGGTGACAGC
CTTTCGCCCCAGGCACAGCAGGTGCTGGACAGGCTGGCGGATTTTGTGAGCGCGCATATGGACATGCCCCGCGTACTTGA
CGCCGCCGCAAGCGCCCCCCCGCTGGAAGCTGAAGCCTTCTGGCCGGAACCTGCCGATGCCGCGGGCAGTTGTTACGACC
TTGCGTCCCCGGCCGGGGCAGAACCTGCCGGGCAGGCCGCCGCATGCACACCTGATGGCAGCGCTGTGGCCTCCCCCTGC
GTCTTTTGCGTCCCTTCCGCCCTGGGCGCGCGGCCGCGTATAGGCTACGTGCGTGATGCCGCCCTGTGGTTTTATTATGA
GGAGAATCTGGAGGCCCTGCGCCGGGCCGGGGCAGATCTTGTGCGGCTTTCGCTCCTGGATGCGGAGTATCGGCCTGCCG
AGGCAGAGGGGGAGCCGGGGGCTTCTTCAGGCCCGGCCTGTCGCGCTCCCTGGCCGCAGGTGAATGCCCTGTACCTGGGC
GGGGGCTTTCCTGAAGATCATGCAGAGGCTTTAAGTCGTTCGCCGCTGCTGGGGCAGATTGCGGCATGGGCGGAACTGGG
TATGCCCATATATGCCGAGTGTGGCGGTTTTATGGTGCTTTCGCGCGGCATTGAGCGTCAGGAAACAGCGTGGCCCATGA
GCGGCATCTTGCCGGTAACCGCTGTTTTTTGCCCGAAGCCGCAGGGGCTTGGCTATGTGCGGGGCCGTATTACGGCTCCC
AATCCTTTTTTTGCACCCGGCACAGAACTGCGTGGACACGAATTTCATTATTCCCGTTGCCGGTGGGAAGTTTCGGACAG
TTGGAGCCATAATTCCGGCCATGCGCACTGGGCCATGCAACTGGACAAGGGGCAGGGCATGGGACCTCCACCCGGTTCGC
CGTTGCATCCGGAGCCGGGCAAGGATGGCGGCGTACACATACCGCTTCGGGTGGACGGCCTTGTTTTTCGTAATGTATGG
GCTTCATATACCCATATTTTCGCCCCGGCCGCACCGGGCTGGGCAGAAAATTTCGTGAACGCGGCCCGCAGCTTTGCCGC
ACGGAACCGGAGAGAATGCCATGAATAA

Upstream 100 bases:

>100_bases
GCTGTCGTGTGGTTGGGCACCCGCATGAGCGCCTTGCAAACATTGCCGGTGCGCATTTTCAATCTTGAAATGGTCCAGCG
CCCCGATCTCACCCGTCACC

Downstream 100 bases:

>100_bases
CGCTAAAGTCTCCATCATTATTCCTGTCTGGAATCTCTGGGACATGACCGCCGCCTGTCTGCGCTCCCTGGCCATGCACA
CACGGGAGGAGAATGTGGAA

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MRNAMSHTCHISEGRNSRSVPESMPRLCVTALSGGGGKTLLSLGICRAFVRSGLVVQPFKKGPDYIDAAWLRLAAGRPAA
NLDPYFLEAPRLRALFVHAMRSAAAQRVEDIATGGQPAAAGRRLLGLVEGNRGFFDGMDARGSCSTAELSRVLACPVVIS
VDCTKMTRTAAALVRGMLYFETGIRFAGVVLNQVGSSRHERILRQALEEHTDVPVLGALPRLAENPLPERHMGIASCGDS
LSPQAQQVLDRLADFVSAHMDMPRVLDAAASAPPLEAEAFWPEPADAAGSCYDLASPAGAEPAGQAAACTPDGSAVASPC
VFCVPSALGARPRIGYVRDAALWFYYEENLEALRRAGADLVRLSLLDAEYRPAEAEGEPGASSGPACRAPWPQVNALYLG
GGFPEDHAEALSRSPLLGQIAAWAELGMPIYAECGGFMVLSRGIERQETAWPMSGILPVTAVFCPKPQGLGYVRGRITAP
NPFFAPGTELRGHEFHYSRCRWEVSDSWSHNSGHAHWAMQLDKGQGMGPPPGSPLHPEPGKDGGVHIPLRVDGLVFRNVW
ASYTHIFAPAAPGWAENFVNAARSFAARNRRECHE

Sequences:

>Translated_595_residues
MRNAMSHTCHISEGRNSRSVPESMPRLCVTALSGGGGKTLLSLGICRAFVRSGLVVQPFKKGPDYIDAAWLRLAAGRPAA
NLDPYFLEAPRLRALFVHAMRSAAAQRVEDIATGGQPAAAGRRLLGLVEGNRGFFDGMDARGSCSTAELSRVLACPVVIS
VDCTKMTRTAAALVRGMLYFETGIRFAGVVLNQVGSSRHERILRQALEEHTDVPVLGALPRLAENPLPERHMGIASCGDS
LSPQAQQVLDRLADFVSAHMDMPRVLDAAASAPPLEAEAFWPEPADAAGSCYDLASPAGAEPAGQAAACTPDGSAVASPC
VFCVPSALGARPRIGYVRDAALWFYYEENLEALRRAGADLVRLSLLDAEYRPAEAEGEPGASSGPACRAPWPQVNALYLG
GGFPEDHAEALSRSPLLGQIAAWAELGMPIYAECGGFMVLSRGIERQETAWPMSGILPVTAVFCPKPQGLGYVRGRITAP
NPFFAPGTELRGHEFHYSRCRWEVSDSWSHNSGHAHWAMQLDKGQGMGPPPGSPLHPEPGKDGGVHIPLRVDGLVFRNVW
ASYTHIFAPAAPGWAENFVNAARSFAARNRRECHE
>Mature_595_residues
MRNAMSHTCHISEGRNSRSVPESMPRLCVTALSGGGGKTLLSLGICRAFVRSGLVVQPFKKGPDYIDAAWLRLAAGRPAA
NLDPYFLEAPRLRALFVHAMRSAAAQRVEDIATGGQPAAAGRRLLGLVEGNRGFFDGMDARGSCSTAELSRVLACPVVIS
VDCTKMTRTAAALVRGMLYFETGIRFAGVVLNQVGSSRHERILRQALEEHTDVPVLGALPRLAENPLPERHMGIASCGDS
LSPQAQQVLDRLADFVSAHMDMPRVLDAAASAPPLEAEAFWPEPADAAGSCYDLASPAGAEPAGQAAACTPDGSAVASPC
VFCVPSALGARPRIGYVRDAALWFYYEENLEALRRAGADLVRLSLLDAEYRPAEAEGEPGASSGPACRAPWPQVNALYLG
GGFPEDHAEALSRSPLLGQIAAWAELGMPIYAECGGFMVLSRGIERQETAWPMSGILPVTAVFCPKPQGLGYVRGRITAP
NPFFAPGTELRGHEFHYSRCRWEVSDSWSHNSGHAHWAMQLDKGQGMGPPPGSPLHPEPGKDGGVHIPLRVDGLVFRNVW
ASYTHIFAPAAPGWAENFVNAARSFAARNRRECHE

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 63726; Mature: 63726

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNAMSHTCHISEGRNSRSVPESMPRLCVTALSGGGGKTLLSLGICRAFVRSGLVVQPFK
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEECCC
KGPDYIDAAWLRLAAGRPAANLDPYFLEAPRLRALFVHAMRSAAAQRVEDIATGGQPAAA
CCCCHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
GRRLLGLVEGNRGFFDGMDARGSCSTAELSRVLACPVVISVDCTKMTRTAAALVRGMLYF
HHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHH
ETGIRFAGVVLNQVGSSRHERILRQALEEHTDVPVLGALPRLAENPLPERHMGIASCGDS
HHCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCHHHCCHHHCCCC
LSPQAQQVLDRLADFVSAHMDMPRVLDAAASAPPLEAEAFWPEPADAAGSCYDLASPAGA
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCC
EPAGQAAACTPDGSAVASPCVFCVPSALGARPRIGYVRDAALWFYYEENLEALRRAGADL
CCCCCCEEECCCCCHHHCCHHHHHHHHHCCCCCCCEEEEHEEEEEEHHHHHHHHHCCCCE
VRLSLLDAEYRPAEAEGEPGASSGPACRAPWPQVNALYLGGGFPEDHAEALSRSPLLGQI
EEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCHHHH
AAWAELGMPIYAECGGFMVLSRGIERQETAWPMSGILPVTAVFCPKPQGLGYVRGRITAP
HHHHHHCCCHHHHCCCEEEECCCCCHHHHCCCCCCCCHHHEEECCCCCCCCEEEEEEECC
NPFFAPGTELRGHEFHYSRCRWEVSDSWSHNSGHAHWAMQLDKGQGMGPPPGSPLHPEPG
CCCCCCCCCCCCCCEEHHHEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
KDGGVHIPLRVDGLVFRNVWASYTHIFAPAAPGWAENFVNAARSFAARNRRECHE
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNAMSHTCHISEGRNSRSVPESMPRLCVTALSGGGGKTLLSLGICRAFVRSGLVVQPFK
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEECCC
KGPDYIDAAWLRLAAGRPAANLDPYFLEAPRLRALFVHAMRSAAAQRVEDIATGGQPAAA
CCCCHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
GRRLLGLVEGNRGFFDGMDARGSCSTAELSRVLACPVVISVDCTKMTRTAAALVRGMLYF
HHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHH
ETGIRFAGVVLNQVGSSRHERILRQALEEHTDVPVLGALPRLAENPLPERHMGIASCGDS
HHCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCHHHCCHHHCCCC
LSPQAQQVLDRLADFVSAHMDMPRVLDAAASAPPLEAEAFWPEPADAAGSCYDLASPAGA
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCC
EPAGQAAACTPDGSAVASPCVFCVPSALGARPRIGYVRDAALWFYYEENLEALRRAGADL
CCCCCCEEECCCCCHHHCCHHHHHHHHHCCCCCCCEEEEHEEEEEEHHHHHHHHHCCCCE
VRLSLLDAEYRPAEAEGEPGASSGPACRAPWPQVNALYLGGGFPEDHAEALSRSPLLGQI
EEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCHHHH
AAWAELGMPIYAECGGFMVLSRGIERQETAWPMSGILPVTAVFCPKPQGLGYVRGRITAP
HHHHHHCCCHHHHCCCEEEECCCCCHHHHCCCCCCCCHHHEEECCCCCCCCEEEEEEECC
NPFFAPGTELRGHEFHYSRCRWEVSDSWSHNSGHAHWAMQLDKGQGMGPPPGSPLHPEPG
CCCCCCCCCCCCCCEEHHHEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
KDGGVHIPLRVDGLVFRNVWASYTHIFAPAAPGWAENFVNAARSFAARNRRECHE
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA