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The map label for this gene is ynaI [H]

Identifier: 220905482

GI number: 220905482

Start: 2677910

End: 2678929

Strand: Reverse

Name: ynaI [H]

Synonym: Ddes_2220

Alternate gene names: 220905482

Gene position: 2678929-2677910 (Counterclockwise)

Preceding gene: 220905483

Following gene: 220905481

Centisome position: 93.23

GC content: 51.08

Gene sequence:

>1020_bases
ATGGACGAAAAAAAGATATTTGAGTTTCTCACTGATGGCTACGCCATTGCCGCCGTGGTAACGGCCATACTGTTCTATTT
CACCATACGGGGGCAGAAGCGCAGTGCCAATACGGCCATGCATCTGACGCGCGTTTGCGCTGCCTGCGCCCTTGTTATGG
CCATAAGTCTTTGTGCGCGGGAACTGGTGGACAAGTTCGGGGCAACTTTTATCAACCCGCGCTACATCAATATTTTCCAG
CATGTGGCCATTGTTCTTATCCTCATCCGTGAATCCTTTCTGGGAATCGACCGCTTTTGCGATCATCTTGCCAGAACCAG
CGGCGACGCCACTTCGGCGCGCATTGTGTCACGCCTGCTCAAAGCCTCCATCTGCCTGTGCGCCATACTGTTTTTCGGCG
AATATATGGGCATAAGCTTTGCTGGACTGCTGACGTTCGGCGGCATCGGCGGCATTGCCATCGGTCTGGCGGGCAAGAAT
ATTTTGGGCAACTTTTTTTCAGGGCTGATGCTGTATTTTGACCGCCCCTTCAATATCGGCGACTGGATAAAATCGCCTGA
TCGCAATATTGAAGGCACGGTGGTGGAGATCGGCTGGCGCATGTCCAAGATCATGACATTCGAGCATTACCCCGTGTACG
TGCCCAACGATATTTTTTCATCCATTTGCATCGAAAATGTGGGGCGCATAGCCAACTATCGTATCAAGCTGCAGATAGGC
CTGCGCTATGAGGATGCGGACAGGATTCAGGCTGTTGCCGATGCTCTGAAAAAAATGCTCCACGATGAGCCGCGTATTGA
CAAGGGGCAGGAAATCCTTGTCGTTTTTAACGAATTTGCCTCTTCATCCCTGAATATCCTGATCTACTGCTACGCAAAAA
CGACCAACTGGGCGCAGTTTATGCAAACGCAGCACGATGTGTATCTCGGCATCGTTTCGGTGGTGCACGGCCTTGGTGCG
GATTTTGCTTTTCCCACGCAAACGCTTTATCTCGAAAAAGACGAAAACAAGCCCGAATAG

Upstream 100 bases:

>100_bases
GCGTGAGCGTGTGGGGCGTTGAAAAAATGCCGTCTTCTTAAAAGCCTGCCAGGCGCGATGAAAACATGTTAGGCGCCCGT
GTTTGTTGCGGAAAGGCCAT

Downstream 100 bases:

>100_bases
CGCCGGGGCGGTGCAAGCGTGATTTTTTAGCGGTCAGCTCCCTGATTCTGGTATGGTGGAGAAGGGGTTCATCTGGCCCT
GTAGTTGTGCAGGGGGGCAT

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MDEKKIFEFLTDGYAIAAVVTAILFYFTIRGQKRSANTAMHLTRVCAACALVMAISLCARELVDKFGATFINPRYINIFQ
HVAIVLILIRESFLGIDRFCDHLARTSGDATSARIVSRLLKASICLCAILFFGEYMGISFAGLLTFGGIGGIAIGLAGKN
ILGNFFSGLMLYFDRPFNIGDWIKSPDRNIEGTVVEIGWRMSKIMTFEHYPVYVPNDIFSSICIENVGRIANYRIKLQIG
LRYEDADRIQAVADALKKMLHDEPRIDKGQEILVVFNEFASSSLNILIYCYAKTTNWAQFMQTQHDVYLGIVSVVHGLGA
DFAFPTQTLYLEKDENKPE

Sequences:

>Translated_339_residues
MDEKKIFEFLTDGYAIAAVVTAILFYFTIRGQKRSANTAMHLTRVCAACALVMAISLCARELVDKFGATFINPRYINIFQ
HVAIVLILIRESFLGIDRFCDHLARTSGDATSARIVSRLLKASICLCAILFFGEYMGISFAGLLTFGGIGGIAIGLAGKN
ILGNFFSGLMLYFDRPFNIGDWIKSPDRNIEGTVVEIGWRMSKIMTFEHYPVYVPNDIFSSICIENVGRIANYRIKLQIG
LRYEDADRIQAVADALKKMLHDEPRIDKGQEILVVFNEFASSSLNILIYCYAKTTNWAQFMQTQHDVYLGIVSVVHGLGA
DFAFPTQTLYLEKDENKPE
>Mature_339_residues
MDEKKIFEFLTDGYAIAAVVTAILFYFTIRGQKRSANTAMHLTRVCAACALVMAISLCARELVDKFGATFINPRYINIFQ
HVAIVLILIRESFLGIDRFCDHLARTSGDATSARIVSRLLKASICLCAILFFGEYMGISFAGLLTFGGIGGIAIGLAGKN
ILGNFFSGLMLYFDRPFNIGDWIKSPDRNIEGTVVEIGWRMSKIMTFEHYPVYVPNDIFSSICIENVGRIANYRIKLQIG
LRYEDADRIQAVADALKKMLHDEPRIDKGQEILVVFNEFASSSLNILIYCYAKTTNWAQFMQTQHDVYLGIVSVVHGLGA
DFAFPTQTLYLEKDENKPE

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=315, Percent_Identity=49.2063492063492, Blast_Score=330, Evalue=6e-92,
Organism=Escherichia coli, GI1789291, Length=226, Percent_Identity=25.2212389380531, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 38001; Mature: 38001

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEKKIFEFLTDGYAIAAVVTAILFYFTIRGQKRSANTAMHLTRVCAACALVMAISLCAR
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELVDKFGATFINPRYINIFQHVAIVLILIRESFLGIDRFCDHLARTSGDATSARIVSRLL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHH
KASICLCAILFFGEYMGISFAGLLTFGGIGGIAIGLAGKNILGNFFSGLMLYFDRPFNIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCHH
DWIKSPDRNIEGTVVEIGWRMSKIMTFEHYPVYVPNDIFSSICIENVGRIANYRIKLQIG
HHHCCCCCCCCCEEEEECHHHHHHEEECCCCEEECHHHHHHHHHHHHHHHHCEEEEEEEE
LRYEDADRIQAVADALKKMLHDEPRIDKGQEILVVFNEFASSSLNILIYCYAKTTNWAQF
EEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHCCCCCEEEEEEEECCCCHHHH
MQTQHDVYLGIVSVVHGLGADFAFPTQTLYLEKDENKPE
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDEKKIFEFLTDGYAIAAVVTAILFYFTIRGQKRSANTAMHLTRVCAACALVMAISLCAR
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELVDKFGATFINPRYINIFQHVAIVLILIRESFLGIDRFCDHLARTSGDATSARIVSRLL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHH
KASICLCAILFFGEYMGISFAGLLTFGGIGGIAIGLAGKNILGNFFSGLMLYFDRPFNIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCHH
DWIKSPDRNIEGTVVEIGWRMSKIMTFEHYPVYVPNDIFSSICIENVGRIANYRIKLQIG
HHHCCCCCCCCCEEEEECHHHHHHEEECCCCEEECHHHHHHHHHHHHHHHHCEEEEEEEE
LRYEDADRIQAVADALKKMLHDEPRIDKGQEILVVFNEFASSSLNILIYCYAKTTNWAQF
EEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHCCCCCEEEEEEEECCCCHHHH
MQTQHDVYLGIVSVVHGLGADFAFPTQTLYLEKDENKPE
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]