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The map label for this gene is coaX

Identifier: 220905479

GI number: 220905479

Start: 2673814

End: 2674605

Strand: Reverse

Name: coaX

Synonym: Ddes_2217

Alternate gene names: 220905479

Gene position: 2674605-2673814 (Counterclockwise)

Preceding gene: 220905480

Following gene: 220905478

Centisome position: 93.08

GC content: 63.26

Gene sequence:

>792_bases
ATGCAGCCCGAACTTCTGCTTTTTGATATCGGCAATACTTCCATCAAAATCGGACTGGCGCATGAGCGGCAGGTGGTCAC
TTCCTACACATTGCGCACCGATGCGGGGCAGACGGCGGATGACCTGGGGCTGAAGCTTGCGACCCTGCTCGGGCACGCGG
GCGTTACGCCGCAGAGCCTGCGGGCCTGCGTGGCTTCTTCGGTGGTTCCGGGCTTTGATCCGCTGTTGCGCGAGGCAGTG
GCCCGCTATGTGGACTGCCCCCTGTATCGCGTTGGCGCTGATTTGTCCGTGCCGCTTGAAAACCGCTATGAGCGCCCGGC
CGAGGTCGGGGCCGACAGGCTGGTGGGAGCCTACGCGGCCCGCCGTCTGTATCCGGAATTTCCCGGCCTGCTGGTGGTTG
ATTTCGGCACGGCGGTGACCATTGACTGTGTTAACGGCAACGCCTATATGGGCGGCCTGATTTTTCCCGGCCCGCGTACA
GCGTTAAGCGCCCTTTCGCGTGAGGCGGCCAAGCTGCCCAGGGTCAACCTGGACGTACGGGCCGATGAACCGACCCCGGG
GCGCAGTACGGCCACCAGCATACAGCACGGGCTGGTTTTCGGTTTTGCCTGCATGGTTGAAGGGCTTGCGCAGCGCCTCA
AGCGGCAGTTGCCCGGTCCTGCCAGGGTGCTGGGAACCGGAGGTTTTGCGGCGTCCATCGCCAGGGTAAGTCCGGTCTTC
GACCATGTGTTGCCCGCCTTGCTGCTTGAGGGTTTACGCCGCCTGTACTATGAAGAGCGCACGGCGTTCTGA

Upstream 100 bases:

>100_bases
GCGTATGTCCGGGCCATGCCATGTCCGGGCGCTTGCCTGGAGCGGCCCGATTGAGCATAATCAGCGGGTTGAAACCTTCA
GCTCCATGTGGAGGACTCCC

Downstream 100 bases:

>100_bases
TATGCTGCGGGCGTGTACGGCCTGTTGTTTCCGGTTTTGTCCGGCGTGCGGCGGCATTGCGCAAAGGCAACCTGTGCGCA
TCGGTGCATGGAGCGGTCTT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MQPELLLFDIGNTSIKIGLAHERQVVTSYTLRTDAGQTADDLGLKLATLLGHAGVTPQSLRACVASSVVPGFDPLLREAV
ARYVDCPLYRVGADLSVPLENRYERPAEVGADRLVGAYAARRLYPEFPGLLVVDFGTAVTIDCVNGNAYMGGLIFPGPRT
ALSALSREAAKLPRVNLDVRADEPTPGRSTATSIQHGLVFGFACMVEGLAQRLKRQLPGPARVLGTGGFAASIARVSPVF
DHVLPALLLEGLRRLYYEERTAF

Sequences:

>Translated_263_residues
MQPELLLFDIGNTSIKIGLAHERQVVTSYTLRTDAGQTADDLGLKLATLLGHAGVTPQSLRACVASSVVPGFDPLLREAV
ARYVDCPLYRVGADLSVPLENRYERPAEVGADRLVGAYAARRLYPEFPGLLVVDFGTAVTIDCVNGNAYMGGLIFPGPRT
ALSALSREAAKLPRVNLDVRADEPTPGRSTATSIQHGLVFGFACMVEGLAQRLKRQLPGPARVLGTGGFAASIARVSPVF
DHVLPALLLEGLRRLYYEERTAF
>Mature_263_residues
MQPELLLFDIGNTSIKIGLAHERQVVTSYTLRTDAGQTADDLGLKLATLLGHAGVTPQSLRACVASSVVPGFDPLLREAV
ARYVDCPLYRVGADLSVPLENRYERPAEVGADRLVGAYAARRLYPEFPGLLVVDFGTAVTIDCVNGNAYMGGLIFPGPRT
ALSALSREAAKLPRVNLDVRADEPTPGRSTATSIQHGLVFGFACMVEGLAQRLKRQLPGPARVLGTGGFAASIARVSPVF
DHVLPALLLEGLRRLYYEERTAF

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_DESDA (B8J468)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480791.1
- GeneID:   7285933
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_2217
- HOGENOM:   HBG634537
- ProtClustDB:   PRK13321
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28245; Mature: 28245

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: ACT_SITE 112-112 BINDING 103-103 BINDING 137-137 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPELLLFDIGNTSIKIGLAHERQVVTSYTLRTDAGQTADDLGLKLATLLGHAGVTPQSL
CCCCEEEEECCCCEEEEEECCCHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHH
RACVASSVVPGFDPLLREAVARYVDCPLYRVGADLSVPLENRYERPAEVGADRLVGAYAA
HHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHH
RRLYPEFPGLLVVDFGTAVTIDCVNGNAYMGGLIFPGPRTALSALSREAAKLPRVNLDVR
HHHCCCCCCEEEEECCCEEEEEEECCCEEECCEECCCHHHHHHHHHHHHHHCCCCCEEEE
ADEPTPGRSTATSIQHGLVFGFACMVEGLAQRLKRQLPGPARVLGTGGFAASIARVSPVF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
DHVLPALLLEGLRRLYYEERTAF
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQPELLLFDIGNTSIKIGLAHERQVVTSYTLRTDAGQTADDLGLKLATLLGHAGVTPQSL
CCCCEEEEECCCCEEEEEECCCHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHH
RACVASSVVPGFDPLLREAVARYVDCPLYRVGADLSVPLENRYERPAEVGADRLVGAYAA
HHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHH
RRLYPEFPGLLVVDFGTAVTIDCVNGNAYMGGLIFPGPRTALSALSREAAKLPRVNLDVR
HHHCCCCCCEEEEECCCEEEEEEECCCEEECCEECCCHHHHHHHHHHHHHHCCCCCEEEE
ADEPTPGRSTATSIQHGLVFGFACMVEGLAQRLKRQLPGPARVLGTGGFAASIARVSPVF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
DHVLPALLLEGLRRLYYEERTAF
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA