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The map label for this gene is yqhT [H]

Identifier: 220905460

GI number: 220905460

Start: 2649929

End: 2651002

Strand: Reverse

Name: yqhT [H]

Synonym: Ddes_2198

Alternate gene names: 220905460

Gene position: 2651002-2649929 (Counterclockwise)

Preceding gene: 220905467

Following gene: 220905458

Centisome position: 92.26

GC content: 61.82

Gene sequence:

>1074_bases
ATGAAGCAGATATATGCCGCCCGCCGCGAACAGCTTCGCCGGGCCATGCACAGGCGCGGCCTGGACGCGCTGCTTGTCAG
CCAGGCCGCCAACCGTTTTTACCTTTCAGGTTTTGAGCTGCACGATCCGCAGTATAACGAAAGCGCCGGGCGGCTGGTGA
TTACCGCCGACGGTCGCGACTGGCTGGCCACAGACCCCCGCTATCTGGATGCCGCCGTTCGCCTGTGGGATGAGGAGCGT
GTTTTTATCTATGGCGGTTACGCAGCCAGGGATATCTACGGACTGCTGCGGGACTGCGGCGGACGCATCGGCATTGAGGC
GCAGGGTACGACTCTGGCCTTTGCCCGTGATCTGGCTGCGGCCGGGCCGGGTTTGTACTGCGAGGCTGCCGATGGCCTGG
TGGAACATCTGCGGCGTATCAAGGACCCCTGCGAAGTGGCGGCGCTGGAAAAATCTTTTGCGCTCAACCATAAGCTGTTG
CAGTGGATTGAAGGCCAGCTTGAGCCGGGGCGGACTGAAAGCCGGGTAAGCTGGCTTATTGAAAAATTCTTTCGCGAAAA
CGGCGCTTCGGAACTGGCCTTTGCCAATATTGTGGCTGTAGGCAAGAATGCGGCCCTGCCCCACGCCATACCGGGGGATG
AGCCTGTGATCGACAACTGCCCGGTACTTGTAGATATTGGCTGCCGGGTGGATGATTACTGCTCGGACCAGACCCGCACC
TTCTGGGTGGGGCAGCAGCCCACAGACGCCTTCCGCCGTACCTATGACCTTGTGCGTCAGGCGCAGACCTTGGCCATAGA
ATCCATGCGCCCCGGGCAGCCGCTGAGGGATGCTTACGGCCATGCGCGGGCAGTATTTGAAAAAGCCGGTACCGCCGATG
CCTTTACCCACGGGCTGGGCCACGGCGTGGGGCTTGAAACCCACGAGGCCCCCAGCCTTTCACCGCGTGCCGAAGGCGTG
CTTGAGCCGGGGATGGTGGTTACCGTGGAGCCGGGCCTGTATTACCGCCAGTGGGGTGGGGTGCGCTGGGAGTACACCGT
GCTGGTGGAAGAAGACGGCGTGCGCATTCTATAG

Upstream 100 bases:

>100_bases
TGCTGCGGCCGCTGCTGTTCGCGACGGGCTGCTGGCGGCGGATATTTTTCAACTTTTCAGGGCTGTTCGCACGCGCTATA
CTGGCGGCAGGAGAATACTC

Downstream 100 bases:

>100_bases
GAGTGGTGGCAAAATCCCCGGCTGGTAAAACGCCGCCGGGGCTGTCACGGAAGGATTGCTGTATTCAGCGCGATTGCGCG
GAAACGGTTTTTATGCCGCC

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKQIYAARREQLRRAMHRRGLDALLVSQAANRFYLSGFELHDPQYNESAGRLVITADGRDWLATDPRYLDAAVRLWDEER
VFIYGGYAARDIYGLLRDCGGRIGIEAQGTTLAFARDLAAAGPGLYCEAADGLVEHLRRIKDPCEVAALEKSFALNHKLL
QWIEGQLEPGRTESRVSWLIEKFFRENGASELAFANIVAVGKNAALPHAIPGDEPVIDNCPVLVDIGCRVDDYCSDQTRT
FWVGQQPTDAFRRTYDLVRQAQTLAIESMRPGQPLRDAYGHARAVFEKAGTADAFTHGLGHGVGLETHEAPSLSPRAEGV
LEPGMVVTVEPGLYYRQWGGVRWEYTVLVEEDGVRIL

Sequences:

>Translated_357_residues
MKQIYAARREQLRRAMHRRGLDALLVSQAANRFYLSGFELHDPQYNESAGRLVITADGRDWLATDPRYLDAAVRLWDEER
VFIYGGYAARDIYGLLRDCGGRIGIEAQGTTLAFARDLAAAGPGLYCEAADGLVEHLRRIKDPCEVAALEKSFALNHKLL
QWIEGQLEPGRTESRVSWLIEKFFRENGASELAFANIVAVGKNAALPHAIPGDEPVIDNCPVLVDIGCRVDDYCSDQTRT
FWVGQQPTDAFRRTYDLVRQAQTLAIESMRPGQPLRDAYGHARAVFEKAGTADAFTHGLGHGVGLETHEAPSLSPRAEGV
LEPGMVVTVEPGLYYRQWGGVRWEYTVLVEEDGVRIL
>Mature_357_residues
MKQIYAARREQLRRAMHRRGLDALLVSQAANRFYLSGFELHDPQYNESAGRLVITADGRDWLATDPRYLDAAVRLWDEER
VFIYGGYAARDIYGLLRDCGGRIGIEAQGTTLAFARDLAAAGPGLYCEAADGLVEHLRRIKDPCEVAALEKSFALNHKLL
QWIEGQLEPGRTESRVSWLIEKFFRENGASELAFANIVAVGKNAALPHAIPGDEPVIDNCPVLVDIGCRVDDYCSDQTRT
FWVGQQPTDAFRRTYDLVRQAQTLAIESMRPGQPLRDAYGHARAVFEKAGTADAFTHGLGHGVGLETHEAPSLSPRAEGV
LEPGMVVTVEPGLYYRQWGGVRWEYTVLVEEDGVRIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI264681563, Length=206, Percent_Identity=31.0679611650485, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788728, Length=225, Percent_Identity=38.2222222222222, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1789275, Length=249, Percent_Identity=28.9156626506024, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786364, Length=246, Percent_Identity=23.5772357723577, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790282, Length=226, Percent_Identity=25.6637168141593, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509539, Length=235, Percent_Identity=29.3617021276596, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323273, Length=241, Percent_Identity=24.4813278008299, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320922, Length=242, Percent_Identity=25.2066115702479, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=297, Percent_Identity=23.2323232323232, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920384, Length=252, Percent_Identity=27.3809523809524, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357079, Length=291, Percent_Identity=25.085910652921, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39730; Mature: 39730

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIYAARREQLRRAMHRRGLDALLVSQAANRFYLSGFELHDPQYNESAGRLVITADGRD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCEEECCCCCCCCCCEEEEEECCCC
WLATDPRYLDAAVRLWDEERVFIYGGYAARDIYGLLRDCGGRIGIEAQGTTLAFARDLAA
CCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
AGPGLYCEAADGLVEHLRRIKDPCEVAALEKSFALNHKLLQWIEGQLEPGRTESRVSWLI
CCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
EKFFRENGASELAFANIVAVGKNAALPHAIPGDEPVIDNCPVLVDIGCRVDDYCSDQTRT
HHHHHHCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEE
FWVGQQPTDAFRRTYDLVRQAQTLAIESMRPGQPLRDAYGHARAVFEKAGTADAFTHGLG
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCC
HGVGLETHEAPSLSPRAEGVLEPGMVVTVEPGLYYRQWGGVRWEYTVLVEEDGVRIL
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEHHCCCCEEEEEEEEECCCCEEC
>Mature Secondary Structure
MKQIYAARREQLRRAMHRRGLDALLVSQAANRFYLSGFELHDPQYNESAGRLVITADGRD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCEEECCCCCCCCCCEEEEEECCCC
WLATDPRYLDAAVRLWDEERVFIYGGYAARDIYGLLRDCGGRIGIEAQGTTLAFARDLAA
CCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
AGPGLYCEAADGLVEHLRRIKDPCEVAALEKSFALNHKLLQWIEGQLEPGRTESRVSWLI
CCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
EKFFRENGASELAFANIVAVGKNAALPHAIPGDEPVIDNCPVLVDIGCRVDDYCSDQTRT
HHHHHHCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEE
FWVGQQPTDAFRRTYDLVRQAQTLAIESMRPGQPLRDAYGHARAVFEKAGTADAFTHGLG
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCC
HGVGLETHEAPSLSPRAEGVLEPGMVVTVEPGLYYRQWGGVRWEYTVLVEEDGVRIL
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEHHCCCCEEEEEEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]