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The map label for this gene is hyuA [H]

Identifier: 220905404

GI number: 220905404

Start: 2581571

End: 2583652

Strand: Reverse

Name: hyuA [H]

Synonym: Ddes_2142

Alternate gene names: 220905404

Gene position: 2583652-2581571 (Counterclockwise)

Preceding gene: 220905412

Following gene: 220905403

Centisome position: 89.92

GC content: 66.67

Gene sequence:

>2082_bases
ATGAAATACACAGACATGAAAAATACGGCAGATACTTCCGTATATTTGCTGGGAATCGATGCCGGAGGAACCCATACCGA
TGCGGTTTTGCTGATGGAGGACCCCGGGGGGCATCCGTCCGGCAGGGCGGACGCGTCGCCCGAAGGGCATGCCGCAGCTG
CCCTGAACGCCGCTGACGACACACATGTGGCATACGCGCCCCATGTATCGGAACAGCCGGAAAAACAGGCTGTTCCGGGC
GCGGCGTTGCCCCGTATGCGTATTCTGGCCGCTGCCAAAACGCCCACGCGGCATGATGATATGCCCGCGTCCATTGGCGA
GGTGCTGGCGGCCCTGACAACCGCGCTGGACAGTGACCCGATCCTGGCCACCTCTGGCGGCGCGGCGCTGCTCGGGCGGG
TGAGCCGGGTCACCCTTGGGGCTACGCTGGCTGTCAACGCCCTTGTGCAGGGCAAGGCTGATGCCGTGGGACTGGCCTTG
TCTGCCGGGCCGGGGCTTGCTCCCGGCCGTTTTGCCCTGGGGCGGCATGTATGTGTAGTTCCCGGCGGTCTTGATCACAG
GGGGGTTGAAGTCAGCCCGCTGGATGTTGCGGGCCTGGAGCGTCAGGCTGCCCTGTGGAAAGAGGAAGGCATCACCGCCG
TGGCTTGCGTGAGCAAGTTTTCGCCGCGTAATCCGGCGCACGAGCAGGCCATGGCCCGGGCTGTGGCGCGCGCGTACGGC
CCTTCCTTGCGCCGGGATGCACCCTCGGACCGCGTACCGGAGGCAGAACCAGCCGTGCCGGGCATTACTGAGGGGCACAG
GCTTTCCGGCCGTCTCAGCTTTCCGCGGCGTATCGCCACCGCCTATTTCAACGCTGCCGTGCAGCGCCTGCACGTCAGTT
TTCTGGAGGCCGCGGAGAGCGCCCTTGCCCGGGCCGGAGTATCCGCCGCGGTGCGCCTGCTCAAGGCTGACGGCGGGGCC
GTGCCGCTGAGCCTTTCACGGCAGGAGCCGGTGCAGTCCATCCTTTCCGGCCCGGCAGCCAGCGTTATGGGCGTGCTGGC
TTTGTGTCCGGCCGCGTGCCAGGGCTGCGGGCTGCTGCTGGATATGGGCGGCACCACCACAGACATGGCCCTTGTGGCGG
ACGGCTCCCCGGTGGTGGACAGGGACGGCATGGTCCTTCAGGGACGGCGTACGCTGGTGCGCGCGCTGGCTTCGGTTTCC
ATCGGCGTGGGTGGTGATTCGCTTGTCAGCGTCGAGGGCAGCGGCCATGAGGCCGTAGTGCGCGTGGGACCGCTGCGGCA
GGGACCTGCCGTGGCCTTTGGCGGCAGCCTGCCAACCCTGCTGGATGCCCTCAACACACTGCACAGCCAACCCTGTTCCG
GGTTGGAAAATTTAACGGAAAACCCGGCGGCCAACGCGGCAGAAAATCCGGCAGCAAGCGGCGCTGCGGCACAGGCCACC
GCACAACTTGCAAAAACAGCAGGGGATGTGGCTGCTTCGGTGGAGAGCATGGGGCATCTGGCTCGGCGGCACGGCCTTGC
ACCCCAGGTTCTGGCCCGCAAGGCTGTGGACGACGCCCTCGCCCGGATAGTTGCAGCTGCCCATGAACTGGTAGAGGACA
TCAACGCCCGTCCCATTTATACCCTTGCGGGGCTGAAGGCGCTGCGTCAGGCGCGGCCCCTGCACGCCTGGCTCATGGGC
GGCCCGGCAGACTGCATGAGAACGCACCTGGCCGCTGCGCTGGGCCTGCCCGTAAAATGCCCGCCCCACGCCGCGGTGGC
CAATGCCGTGGGCGCGGCCCTGACCCTGCCCACGGATTCGCTGGAAGTTTACGCAGATACCGGCCGCGGCATTCTGCGCG
TTCCGGCTCTGGACCTGACGGAAAATATCCACCGGGGCTACAGTCTGGACGCCCTTGGTGAACGCGCCCGTGATCTGCTG
CTGGAAAAGCTCGAACGGGGCGGAGCGCACGGGGCCGCAGTGGAGATCACCGGAGCAGAATCGTTCGCCACGCTGGACGA
CAGCGGCCGCAGCAGCCGGGACATGCGCGTGGTCTGTCAGGCTGTGCCGGGACTGGCTGGCCGGGTGGTCCAGAGCCATT
AA

Upstream 100 bases:

>100_bases
GCGGGCCTTGAGCGGCGCGCGCCGCCTCCGGGCAAAGGTCTGGCCCTGGGGCGGCGCATGCCGTATGCTGGGCCTGCCTT
TTTGCGCAATGAGGACAGAT

Downstream 100 bases:

>100_bases
TGTCTGAAATGCGCTCATGCTCTCTGTTTGGTGCGCCAGTGGGTGGCAGCGGCGAACCTGCTTGCCACCTGGCTGACCCC
TGCCCGCCTTGTCATTGCGG

Product: Hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKYTDMKNTADTSVYLLGIDAGGTHTDAVLLMEDPGGHPSGRADASPEGHAAAALNAADDTHVAYAPHVSEQPEKQAVPG
AALPRMRILAAAKTPTRHDDMPASIGEVLAALTTALDSDPILATSGGAALLGRVSRVTLGATLAVNALVQGKADAVGLAL
SAGPGLAPGRFALGRHVCVVPGGLDHRGVEVSPLDVAGLERQAALWKEEGITAVACVSKFSPRNPAHEQAMARAVARAYG
PSLRRDAPSDRVPEAEPAVPGITEGHRLSGRLSFPRRIATAYFNAAVQRLHVSFLEAAESALARAGVSAAVRLLKADGGA
VPLSLSRQEPVQSILSGPAASVMGVLALCPAACQGCGLLLDMGGTTTDMALVADGSPVVDRDGMVLQGRRTLVRALASVS
IGVGGDSLVSVEGSGHEAVVRVGPLRQGPAVAFGGSLPTLLDALNTLHSQPCSGLENLTENPAANAAENPAASGAAAQAT
AQLAKTAGDVAASVESMGHLARRHGLAPQVLARKAVDDALARIVAAAHELVEDINARPIYTLAGLKALRQARPLHAWLMG
GPADCMRTHLAAALGLPVKCPPHAAVANAVGAALTLPTDSLEVYADTGRGILRVPALDLTENIHRGYSLDALGERARDLL
LEKLERGGAHGAAVEITGAESFATLDDSGRSSRDMRVVCQAVPGLAGRVVQSH

Sequences:

>Translated_693_residues
MKYTDMKNTADTSVYLLGIDAGGTHTDAVLLMEDPGGHPSGRADASPEGHAAAALNAADDTHVAYAPHVSEQPEKQAVPG
AALPRMRILAAAKTPTRHDDMPASIGEVLAALTTALDSDPILATSGGAALLGRVSRVTLGATLAVNALVQGKADAVGLAL
SAGPGLAPGRFALGRHVCVVPGGLDHRGVEVSPLDVAGLERQAALWKEEGITAVACVSKFSPRNPAHEQAMARAVARAYG
PSLRRDAPSDRVPEAEPAVPGITEGHRLSGRLSFPRRIATAYFNAAVQRLHVSFLEAAESALARAGVSAAVRLLKADGGA
VPLSLSRQEPVQSILSGPAASVMGVLALCPAACQGCGLLLDMGGTTTDMALVADGSPVVDRDGMVLQGRRTLVRALASVS
IGVGGDSLVSVEGSGHEAVVRVGPLRQGPAVAFGGSLPTLLDALNTLHSQPCSGLENLTENPAANAAENPAASGAAAQAT
AQLAKTAGDVAASVESMGHLARRHGLAPQVLARKAVDDALARIVAAAHELVEDINARPIYTLAGLKALRQARPLHAWLMG
GPADCMRTHLAAALGLPVKCPPHAAVANAVGAALTLPTDSLEVYADTGRGILRVPALDLTENIHRGYSLDALGERARDLL
LEKLERGGAHGAAVEITGAESFATLDDSGRSSRDMRVVCQAVPGLAGRVVQSH
>Mature_693_residues
MKYTDMKNTADTSVYLLGIDAGGTHTDAVLLMEDPGGHPSGRADASPEGHAAAALNAADDTHVAYAPHVSEQPEKQAVPG
AALPRMRILAAAKTPTRHDDMPASIGEVLAALTTALDSDPILATSGGAALLGRVSRVTLGATLAVNALVQGKADAVGLAL
SAGPGLAPGRFALGRHVCVVPGGLDHRGVEVSPLDVAGLERQAALWKEEGITAVACVSKFSPRNPAHEQAMARAVARAYG
PSLRRDAPSDRVPEAEPAVPGITEGHRLSGRLSFPRRIATAYFNAAVQRLHVSFLEAAESALARAGVSAAVRLLKADGGA
VPLSLSRQEPVQSILSGPAASVMGVLALCPAACQGCGLLLDMGGTTTDMALVADGSPVVDRDGMVLQGRRTLVRALASVS
IGVGGDSLVSVEGSGHEAVVRVGPLRQGPAVAFGGSLPTLLDALNTLHSQPCSGLENLTENPAANAAENPAASGAAAQAT
AQLAKTAGDVAASVESMGHLARRHGLAPQVLARKAVDDALARIVAAAHELVEDINARPIYTLAGLKALRQARPLHAWLMG
GPADCMRTHLAAALGLPVKCPPHAAVANAVGAALTLPTDSLEVYADTGRGILRVPALDLTENIHRGYSLDALGERARDLL
LEKLERGGAHGAAVEITGAESFATLDDSGRSSRDMRVVCQAVPGLAGRVVQSH

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 70784; Mature: 70784

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTDMKNTADTSVYLLGIDAGGTHTDAVLLMEDPGGHPSGRADASPEGHAAAALNAADD
CCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCC
THVAYAPHVSEQPEKQAVPGAALPRMRILAAAKTPTRHDDMPASIGEVLAALTTALDSDP
CEEEECCCCCCCCHHHCCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
ILATSGGAALLGRVSRVTLGATLAVNALVQGKADAVGLALSAGPGLAPGRFALGRHVCVV
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHCCEEEEE
PGGLDHRGVEVSPLDVAGLERQAALWKEEGITAVACVSKFSPRNPAHEQAMARAVARAYG
CCCCCCCCEEECCCCHHCCHHHHHHHHHCCCEEEEHHHHCCCCCCHHHHHHHHHHHHHHC
PSLRRDAPSDRVPEAEPAVPGITEGHRLSGRLSFPRRIATAYFNAAVQRLHVSFLEAAES
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALARAGVSAAVRLLKADGGAVPLSLSRQEPVQSILSGPAASVMGVLALCPAACQGCGLLL
HHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEE
DMGGTTTDMALVADGSPVVDRDGMVLQGRRTLVRALASVSIGVGGDSLVSVEGSGHEAVV
ECCCCCCCEEEEECCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEE
RVGPLRQGPAVAFGGSLPTLLDALNTLHSQPCSGLENLTENPAANAAENPAASGAAAQAT
EECCCCCCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
AQLAKTAGDVAASVESMGHLARRHGLAPQVLARKAVDDALARIVAAAHELVEDINARPIY
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLAGLKALRQARPLHAWLMGGPADCMRTHLAAALGLPVKCPPHAAVANAVGAALTLPTDS
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCC
LEVYADTGRGILRVPALDLTENIHRGYSLDALGERARDLLLEKLERGGAHGAAVEITGAE
EEEEECCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SFATLDDSGRSSRDMRVVCQAVPGLAGRVVQSH
CEEECCCCCCCCCHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MKYTDMKNTADTSVYLLGIDAGGTHTDAVLLMEDPGGHPSGRADASPEGHAAAALNAADD
CCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCC
THVAYAPHVSEQPEKQAVPGAALPRMRILAAAKTPTRHDDMPASIGEVLAALTTALDSDP
CEEEECCCCCCCCHHHCCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
ILATSGGAALLGRVSRVTLGATLAVNALVQGKADAVGLALSAGPGLAPGRFALGRHVCVV
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHCCEEEEE
PGGLDHRGVEVSPLDVAGLERQAALWKEEGITAVACVSKFSPRNPAHEQAMARAVARAYG
CCCCCCCCEEECCCCHHCCHHHHHHHHHCCCEEEEHHHHCCCCCCHHHHHHHHHHHHHHC
PSLRRDAPSDRVPEAEPAVPGITEGHRLSGRLSFPRRIATAYFNAAVQRLHVSFLEAAES
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALARAGVSAAVRLLKADGGAVPLSLSRQEPVQSILSGPAASVMGVLALCPAACQGCGLLL
HHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEE
DMGGTTTDMALVADGSPVVDRDGMVLQGRRTLVRALASVSIGVGGDSLVSVEGSGHEAVV
ECCCCCCCEEEEECCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEE
RVGPLRQGPAVAFGGSLPTLLDALNTLHSQPCSGLENLTENPAANAAENPAASGAAAQAT
EECCCCCCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHH
AQLAKTAGDVAASVESMGHLARRHGLAPQVLARKAVDDALARIVAAAHELVEDINARPIY
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLAGLKALRQARPLHAWLMGGPADCMRTHLAAALGLPVKCPPHAAVANAVGAALTLPTDS
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCC
LEVYADTGRGILRVPALDLTENIHRGYSLDALGERARDLLLEKLERGGAHGAAVEITGAE
EEEEECCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SFATLDDSGRSSRDMRVVCQAVPGLAGRVVQSH
CEEECCCCCCCCCHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]