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The map label for this gene is trpB1 [H]

Identifier: 220904854

GI number: 220904854

Start: 1908906

End: 1910096

Strand: Reverse

Name: trpB1 [H]

Synonym: Ddes_1588

Alternate gene names: 220904854

Gene position: 1910096-1908906 (Counterclockwise)

Preceding gene: 220904855

Following gene: 220904853

Centisome position: 66.47

GC content: 60.79

Gene sequence:

>1191_bases
ATGAAGAACAGATATTTTGGTGAATTCGGCGGCTGCTTTGTGCCCGAATTGCTCATGCCGCCGCTTATGGAGGTCGAGGC
GGCCATGCACGACATTTATCCCACAGAGGCCTTTCAGGCTGAACTGGAAAGCCTCCTGCGCAATTATGCCGGGCGTGAGA
CACCGCTGACCCATTGCCCGACCCTGTCGCGGGAACTGGGCTTTGACCTCTGGCTCAAGCGTGAGGACCTGTTGCATACA
GGGGCGCACAAGATCAACAATACCCTGGGGCAGGCGCTGCTTGCCAGGCATATGGGCAAGACGGCCCTGGTGGCTGAAAC
CGGAGCCGGGCAGCACGGTGTTGCCACCGCGGCCTCCGCGGCCCGCCTGGGTATGGAATGCACCATTTATATGGGTGCGG
AAGATGTGGAGCGGCAAGCCCCCAACGTCATGCGCATGAAGCTGCTCGGGGCCACCGTGCACGCGGTGGAAAGCGGTACG
CGCACCCTCAAGGATGCCATTAACGAAGCCCTGCGCGCCTGGATAGGCAGCCAGAAAACAACTCATTACTGCTTTGGAAC
AGCTGCAGGGCCACATCCTTTTCCGCTGTTGGTGCGTGAGCTGCAAAGCGTCATAGGGCGCGAAACACGCGCCCAGATGC
TGGGAAAAACCGGCAGGCTGCCTGATGCCATAGTGGCTTGCGTGGGCGGCGGGTCCAATGCCATCGGCATGTTTTATCCT
TTTCTCGACGATGCCGCAGTGCGCATTGTGGGCGTAGAGGCAGCAGGTACCGGCGAGCCGGGCTGCTTCAACTCCGCGCC
GCTCAACCTCGGCGTTCCCGGTGTGCTGCACGGCGCGTACAGCATGCTTTTGCAGAATGATGACGGCCAGGTGGAGCCTT
CACATTCCATTTCCGCCGGTCTGGATTATCCGGGCGTTGGTCCCGAGCACTCCTGGCTGCACAAAACGGGCCGCGTCCAC
TACGGCATGGTTAAAGACGGCAACGCACTTGCGGCCTTTCAGCGACTATGCCGCGCCGAGGGCATCCTGCCTGCCCTGGA
ATCTTCACATGCGCTGGCCTGGGTGCTGGATCATCCGCATGAGTTCAAGCCCGGCCAGCAGGTGGTGGTCAACCTTTCGG
GCCGCGGTGACAAGGATCTTGGCATTATCAACAAGGCCCTGGGTTTTGCCCTGGGGCAGGACGAGGTGTAG

Upstream 100 bases:

>100_bases
TCAATTCCGGCGTGGAGGATGCGCCGGGGCAGAAAAATGCGCAAAAGCTGGCGGCCGCCCTCGCGGTAGCCGCAAAACAG
AAAGGCAATAGGTACTTGTC

Downstream 100 bases:

>100_bases
TCATGAACCTGCTTGAAGAAAAGATACGTGCGGCCAATGCCGCCGGACGCCCGGCCCTTATCCCTTTTTTGACCGCGGGC
TTTCCCGATCGCGCAACATT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKNRYFGEFGGCFVPELLMPPLMEVEAAMHDIYPTEAFQAELESLLRNYAGRETPLTHCPTLSRELGFDLWLKREDLLHT
GAHKINNTLGQALLARHMGKTALVAETGAGQHGVATAASAARLGMECTIYMGAEDVERQAPNVMRMKLLGATVHAVESGT
RTLKDAINEALRAWIGSQKTTHYCFGTAAGPHPFPLLVRELQSVIGRETRAQMLGKTGRLPDAIVACVGGGSNAIGMFYP
FLDDAAVRIVGVEAAGTGEPGCFNSAPLNLGVPGVLHGAYSMLLQNDDGQVEPSHSISAGLDYPGVGPEHSWLHKTGRVH
YGMVKDGNALAAFQRLCRAEGILPALESSHALAWVLDHPHEFKPGQQVVVNLSGRGDKDLGIINKALGFALGQDEV

Sequences:

>Translated_396_residues
MKNRYFGEFGGCFVPELLMPPLMEVEAAMHDIYPTEAFQAELESLLRNYAGRETPLTHCPTLSRELGFDLWLKREDLLHT
GAHKINNTLGQALLARHMGKTALVAETGAGQHGVATAASAARLGMECTIYMGAEDVERQAPNVMRMKLLGATVHAVESGT
RTLKDAINEALRAWIGSQKTTHYCFGTAAGPHPFPLLVRELQSVIGRETRAQMLGKTGRLPDAIVACVGGGSNAIGMFYP
FLDDAAVRIVGVEAAGTGEPGCFNSAPLNLGVPGVLHGAYSMLLQNDDGQVEPSHSISAGLDYPGVGPEHSWLHKTGRVH
YGMVKDGNALAAFQRLCRAEGILPALESSHALAWVLDHPHEFKPGQQVVVNLSGRGDKDLGIINKALGFALGQDEV
>Mature_396_residues
MKNRYFGEFGGCFVPELLMPPLMEVEAAMHDIYPTEAFQAELESLLRNYAGRETPLTHCPTLSRELGFDLWLKREDLLHT
GAHKINNTLGQALLARHMGKTALVAETGAGQHGVATAASAARLGMECTIYMGAEDVERQAPNVMRMKLLGATVHAVESGT
RTLKDAINEALRAWIGSQKTTHYCFGTAAGPHPFPLLVRELQSVIGRETRAQMLGKTGRLPDAIVACVGGGSNAIGMFYP
FLDDAAVRIVGVEAAGTGEPGCFNSAPLNLGVPGVLHGAYSMLLQNDDGQVEPSHSISAGLDYPGVGPEHSWLHKTGRVH
YGMVKDGNALAAFQRLCRAEGILPALESSHALAWVLDHPHEFKPGQQVVVNLSGRGDKDLGIINKALGFALGQDEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=56.7357512953368, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=52.0833333333333, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42460; Mature: 42460

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRYFGEFGGCFVPELLMPPLMEVEAAMHDIYPTEAFQAELESLLRNYAGRETPLTHCP
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TLSRELGFDLWLKREDLLHTGAHKINNTLGQALLARHMGKTALVAETGAGQHGVATAASA
CHHHHCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
ARLGMECTIYMGAEDVERQAPNVMRMKLLGATVHAVESGTRTLKDAINEALRAWIGSQKT
HHCCCEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
THYCFGTAAGPHPFPLLVRELQSVIGRETRAQMLGKTGRLPDAIVACVGGGSNAIGMFYP
EEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHEEEECCCCCCHHHHHH
FLDDAAVRIVGVEAAGTGEPGCFNSAPLNLGVPGVLHGAYSMLLQNDDGQVEPSHSISAG
HHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCC
LDYPGVGPEHSWLHKTGRVHYGMVKDGNALAAFQRLCRAEGILPALESSHALAWVLDHPH
CCCCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCC
EFKPGQQVVVNLSGRGDKDLGIINKALGFALGQDEV
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNRYFGEFGGCFVPELLMPPLMEVEAAMHDIYPTEAFQAELESLLRNYAGRETPLTHCP
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TLSRELGFDLWLKREDLLHTGAHKINNTLGQALLARHMGKTALVAETGAGQHGVATAASA
CHHHHCCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
ARLGMECTIYMGAEDVERQAPNVMRMKLLGATVHAVESGTRTLKDAINEALRAWIGSQKT
HHCCCEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
THYCFGTAAGPHPFPLLVRELQSVIGRETRAQMLGKTGRLPDAIVACVGGGSNAIGMFYP
EEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHEEEECCCCCCHHHHHH
FLDDAAVRIVGVEAAGTGEPGCFNSAPLNLGVPGVLHGAYSMLLQNDDGQVEPSHSISAG
HHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCC
LDYPGVGPEHSWLHKTGRVHYGMVKDGNALAAFQRLCRAEGILPALESSHALAWVLDHPH
CCCCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCC
EFKPGQQVVVNLSGRGDKDLGIINKALGFALGQDEV
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]