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The map label for this gene is bioB [H]

Identifier: 220904772

GI number: 220904772

Start: 1795556

End: 1796551

Strand: Reverse

Name: bioB [H]

Synonym: Ddes_1504

Alternate gene names: 220904772

Gene position: 1796551-1795556 (Counterclockwise)

Preceding gene: 220904773

Following gene: 220904771

Centisome position: 62.52

GC content: 62.85

Gene sequence:

>996_bases
ATGCGCCGCGAAGACATTCTTGACCTGCTTTTCAACACTCCCTGGCATGAACTGCGCCTGCGTGCCGCTCATGTTCTGGA
GAGTGAAAAAGGTTTTCATGTGCATGTGCGCGGTCTTGTTGAGTTTTCCAGCAACTGCCGCCGCAACTGCCTTTACTGCG
GCTTGCGGGCGGACAACCACAGGCTGCAGCGCTATACGCTTTCCCGGGAACGCATACTTGAAGCGGCCGCGGCGGCGGCC
GCCGCCGGAGCCGACACCATTGTGCTGCAGTCGGGTGAATATGCGGTCAAGCCCGAGTGGCTGGCCCGCGTCATCGCCGA
TATCCGCAGCAGGTCTGACCTTCCGGTGACGCTGAGTGTGGGCGAGCAGCCGGCGGCGGCCTACGCCCTCTGGAAAGAGG
CCGGGGCCGTGCGTTATCTGCTCAAGCACGAAACAGCCGATGCAAAGCTCTATGCTGTCCTGCATCCCGGCCATGATTTG
CGGCAACGCATCGCTTGCCTGCACACGTTGGCTTCTCTCGGTTATGAGTGCGGTTCTGGTTTTATGGTGGGGCTGCCGGG
GCAGCGCCCCGAAAGCCTCGCTGACGATATTCTGCTGGCGCGCCGTCTGCGTGTAGCCATGTGCGGCGTGGGACCGTTCA
TTCCGCAGGCTCATACGCCTTTGGGAAAATCTGTCGGCGGCAGCGCGGCCTTGACGCTGCGAGTCATGGCCGTCCTGCGG
ATTGCCCTGCCCTGGGCCAACATTCCTGCAACTACGGCACTGGCTACCGTTGATGCCGCCAGCGGCCAGCGCGATGGCCT
GCTGGCCGGGGCCAATGTGCTCATGCCGGGCTTCACCCCGTCCGATGTCCGGGAAGATTACTGTATCTACGACAACAAGA
ATCGTGTGGATCTTGCCGCCGCCCGCCAGGCCATTGAAGGTGCTGGCCGACGGCATGCGCTTGACATGCCGCATATGGCA
AACGCCCCTGCCCCGGAGGCGGCAGCGCGGCCATAG

Upstream 100 bases:

>100_bases
GAGGAGCGTACACGGCGTGTATCGGAAAAGCTGCTGGACAAGGTCCGTTCCGGCCAGAGGGATGTGTACTGCTGATACGT
CGCCGCCTCCGGGAGGATTC

Downstream 100 bases:

>100_bases
GCAAGGGTCAAGTTCTGTGCCGGGTTCCGGCTGCACTGTAGGGAGCGTGCGCGCAGAAGCGCGCCGGAAAACTGTTTCAC
CTGTTACCGCCAGGAGGTTG

Product: biotin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRREDILDLLFNTPWHELRLRAAHVLESEKGFHVHVRGLVEFSSNCRRNCLYCGLRADNHRLQRYTLSRERILEAAAAAA
AAGADTIVLQSGEYAVKPEWLARVIADIRSRSDLPVTLSVGEQPAAAYALWKEAGAVRYLLKHETADAKLYAVLHPGHDL
RQRIACLHTLASLGYECGSGFMVGLPGQRPESLADDILLARRLRVAMCGVGPFIPQAHTPLGKSVGGSAALTLRVMAVLR
IALPWANIPATTALATVDAASGQRDGLLAGANVLMPGFTPSDVREDYCIYDNKNRVDLAAARQAIEGAGRRHALDMPHMA
NAPAPEAAARP

Sequences:

>Translated_331_residues
MRREDILDLLFNTPWHELRLRAAHVLESEKGFHVHVRGLVEFSSNCRRNCLYCGLRADNHRLQRYTLSRERILEAAAAAA
AAGADTIVLQSGEYAVKPEWLARVIADIRSRSDLPVTLSVGEQPAAAYALWKEAGAVRYLLKHETADAKLYAVLHPGHDL
RQRIACLHTLASLGYECGSGFMVGLPGQRPESLADDILLARRLRVAMCGVGPFIPQAHTPLGKSVGGSAALTLRVMAVLR
IALPWANIPATTALATVDAASGQRDGLLAGANVLMPGFTPSDVREDYCIYDNKNRVDLAAARQAIEGAGRRHALDMPHMA
NAPAPEAAARP
>Mature_331_residues
MRREDILDLLFNTPWHELRLRAAHVLESEKGFHVHVRGLVEFSSNCRRNCLYCGLRADNHRLQRYTLSRERILEAAAAAA
AAGADTIVLQSGEYAVKPEWLARVIADIRSRSDLPVTLSVGEQPAAAYALWKEAGAVRYLLKHETADAKLYAVLHPGHDL
RQRIACLHTLASLGYECGSGFMVGLPGQRPESLADDILLARRLRVAMCGVGPFIPQAHTPLGKSVGGSAALTLRVMAVLR
IALPWANIPATTALATVDAASGQRDGLLAGANVLMPGFTPSDVREDYCIYDNKNRVDLAAARQAIEGAGRRHALDMPHMA
NAPAPEAAARP

Specific function: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism [H]

COG id: COG0502

COG function: function code H; Biotin synthase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Biotin synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR010722
- InterPro:   IPR002684
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06968 BATS; PF04055 Radical_SAM [H]

EC number: =2.8.1.6 [H]

Molecular weight: Translated: 35898; Mature: 35898

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRREDILDLLFNTPWHELRLRAAHVLESEKGFHVHVRGLVEFSSNCRRNCLYCGLRADNH
CCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCEEEECCCCCC
RLQRYTLSRERILEAAAAAAAAGADTIVLQSGEYAVKPEWLARVIADIRSRSDLPVTLSV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECHHHHHHHHHHHHCCCCCCEEEEC
GEQPAAAYALWKEAGAVRYLLKHETADAKLYAVLHPGHDLRQRIACLHTLASLGYECGSG
CCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHCCCC
FMVGLPGQRPESLADDILLARRLRVAMCGVGPFIPQAHTPLGKSVGGSAALTLRVMAVLR
CEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IALPWANIPATTALATVDAASGQRDGLLAGANVLMPGFTPSDVREDYCIYDNKNRVDLAA
HHCCCCCCCCHHHHEEEECCCCCCCCEEECCCEEECCCCHHHHCCCEEEECCCCCCHHHH
ARQAIEGAGRRHALDMPHMANAPAPEAAARP
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRREDILDLLFNTPWHELRLRAAHVLESEKGFHVHVRGLVEFSSNCRRNCLYCGLRADNH
CCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCEEEECCCCCC
RLQRYTLSRERILEAAAAAAAAGADTIVLQSGEYAVKPEWLARVIADIRSRSDLPVTLSV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECHHHHHHHHHHHHCCCCCCEEEEC
GEQPAAAYALWKEAGAVRYLLKHETADAKLYAVLHPGHDLRQRIACLHTLASLGYECGSG
CCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHCCCC
FMVGLPGQRPESLADDILLARRLRVAMCGVGPFIPQAHTPLGKSVGGSAALTLRVMAVLR
CEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IALPWANIPATTALATVDAASGQRDGLLAGANVLMPGFTPSDVREDYCIYDNKNRVDLAA
HHCCCCCCCCHHHHEEEECCCCCCCCEEECCCEEECCCCHHHHCCCEEEECCCCCCHHHH
ARQAIEGAGRRHALDMPHMANAPAPEAAARP
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA