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The map label for this gene is stc [H]

Identifier: 220904702

GI number: 220904702

Start: 1716341

End: 1717741

Strand: Reverse

Name: stc [H]

Synonym: Ddes_1434

Alternate gene names: 220904702

Gene position: 1717741-1716341 (Counterclockwise)

Preceding gene: 220904703

Following gene: 220904701

Centisome position: 59.78

GC content: 57.53

Gene sequence:

>1401_bases
ATGGCCGATCACTCTCAGGAACTGCTTTCAAAGCATGTGAAGCGCATACTTGACGCCCTGCCCGAAGGCGTTTTCATCAG
CGATGCTTCGGGAACCAGCCTGCGTGTTAACCGCATGTACGAGCAGTTGACCGGCCTCACACAGGAGCAGGTGCAGGGCA
AGAACGTGCGCTGCCTGGTGGAGGAGGGGGTCTTTGACCACATTCTCAACCCGCAGATAGTACGCACCGGCAGGCCTGCC
ACCCATGTGCAGCAGCTCAAGGACGGCAAAAAGCTGGTGCTGACGGGTTTTCCTGTCTTTGACACGCGTGGCGACCTCTG
CCTTGTGGTCACCTTTGCGCGCGACATCACCCTGCTGGCCCAGTTGCAGGATCAGGTGGCCGGGCAGTGCAGGCTTATCG
ATCAGATCAACGACCAGCTGGCGTATATGACCAGCGAGGGCAACAAGGCGCGAGATCCCATTTATGCCAGTCCTGCCATG
GGGGAGGTGGTTTCGCTGTTGCGACGATTTGCCGCCACAGACGCCACAGTGCTGATCCTGGGCGAAACGGGCGCGGGCAA
AGATGTTTTTGCCCGGTTTACTCATGGCCTATCTGAACGACGCGATAAAATCCTGCTCAAGGTAGACTGTGGCGGCATTT
CCGAAACCCTCACGGAATCGGAACTGTTCGGTTACATGCCCGGTGCTTTTACCGGGGCCTCCAGTAAGGGCAAGGCCGGA
TATTTTGAAATTGCCGATGGCAGCACCATTTTTCTGGATGAAGTGGGCGAACTGCCCCTTTCCATGCAGACGCGGCTTCT
GCGTGTGTTGCAGGATGGCGAAATCATGCGCGTAGGGGCATCCAGCCCGCGCAAGGTGGATGTGCGCATTATCGCGGCCA
CCAACCGCAACCTTGCCGAAAGCGTAGAAGCCGGAACTTTTCGCCGCGACCTCTATTATCGCCTCAATGTGGCCACAGTG
CGCATCCCGTCCCTGCGGGACCGTAAGGAAGATGTGCCTCTGCTGGCCGAGCATTTTTTGGCGCACTATGCGGCCAAGTA
CCATAAGGTCATGGCTTTTATGGATGTCACCCTCAATATGATGGCTGCGTATGCCTGGCCCGGCAACGTGCGTGAACTGC
AGAATATGGTGCACAGTCTGGTCATCACGCTCAATGGCCCGCTCATCACTCCGCGCGATCTGCCCGCACAGGTTACCGGC
GTGACGCATGATGCCTCCCGGTATTCGGAAGACGTGCTTGTGCCCCGTCGCCCGTTGCGGGAAATTATGGCGGAAATGGA
GCGCGACTTTTTGCTCAAGGCCATAGAGGTGCATGGCTCGGTGCAGCGTGTTGCGGAACTTTTTCAGGTTAACCGCAGCA
CCATCTTCAGGAAGCTGCAAGGTACAAGGCAGACACGATGA

Upstream 100 bases:

>100_bases
CAAGGCCGTTACGGACGGGCTGCAAAAGACCGCTCTGGACATTTTGGGGGAGCGGGTGCAGATTCCCCGCTGAATACGCA
GCATTTTACCGGATTGAAAT

Downstream 100 bases:

>100_bases
CCCGTCATGGCAGTGCGGGCGGGATGTTTCGCACGGTTTTGCTCACGGCTGTATGCATGACATTTTTTGCGGCAAACTCG
CTGCTATGTCGCATGGCGCT

Product: Fis family PAS modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MADHSQELLSKHVKRILDALPEGVFISDASGTSLRVNRMYEQLTGLTQEQVQGKNVRCLVEEGVFDHILNPQIVRTGRPA
THVQQLKDGKKLVLTGFPVFDTRGDLCLVVTFARDITLLAQLQDQVAGQCRLIDQINDQLAYMTSEGNKARDPIYASPAM
GEVVSLLRRFAATDATVLILGETGAGKDVFARFTHGLSERRDKILLKVDCGGISETLTESELFGYMPGAFTGASSKGKAG
YFEIADGSTIFLDEVGELPLSMQTRLLRVLQDGEIMRVGASSPRKVDVRIIAATNRNLAESVEAGTFRRDLYYRLNVATV
RIPSLRDRKEDVPLLAEHFLAHYAAKYHKVMAFMDVTLNMMAAYAWPGNVRELQNMVHSLVITLNGPLITPRDLPAQVTG
VTHDASRYSEDVLVPRRPLREIMAEMERDFLLKAIEVHGSVQRVAELFQVNRSTIFRKLQGTRQTR

Sequences:

>Translated_466_residues
MADHSQELLSKHVKRILDALPEGVFISDASGTSLRVNRMYEQLTGLTQEQVQGKNVRCLVEEGVFDHILNPQIVRTGRPA
THVQQLKDGKKLVLTGFPVFDTRGDLCLVVTFARDITLLAQLQDQVAGQCRLIDQINDQLAYMTSEGNKARDPIYASPAM
GEVVSLLRRFAATDATVLILGETGAGKDVFARFTHGLSERRDKILLKVDCGGISETLTESELFGYMPGAFTGASSKGKAG
YFEIADGSTIFLDEVGELPLSMQTRLLRVLQDGEIMRVGASSPRKVDVRIIAATNRNLAESVEAGTFRRDLYYRLNVATV
RIPSLRDRKEDVPLLAEHFLAHYAAKYHKVMAFMDVTLNMMAAYAWPGNVRELQNMVHSLVITLNGPLITPRDLPAQVTG
VTHDASRYSEDVLVPRRPLREIMAEMERDFLLKAIEVHGSVQRVAELFQVNRSTIFRKLQGTRQTR
>Mature_465_residues
ADHSQELLSKHVKRILDALPEGVFISDASGTSLRVNRMYEQLTGLTQEQVQGKNVRCLVEEGVFDHILNPQIVRTGRPAT
HVQQLKDGKKLVLTGFPVFDTRGDLCLVVTFARDITLLAQLQDQVAGQCRLIDQINDQLAYMTSEGNKARDPIYASPAMG
EVVSLLRRFAATDATVLILGETGAGKDVFARFTHGLSERRDKILLKVDCGGISETLTESELFGYMPGAFTGASSKGKAGY
FEIADGSTIFLDEVGELPLSMQTRLLRVLQDGEIMRVGASSPRKVDVRIIAATNRNLAESVEAGTFRRDLYYRLNVATVR
IPSLRDRKEDVPLLAEHFLAHYAAKYHKVMAFMDVTLNMMAAYAWPGNVRELQNMVHSLVITLNGPLITPRDLPAQVTGV
THDASRYSEDVLVPRRPLREIMAEMERDFLLKAIEVHGSVQRVAELFQVNRSTIFRKLQGTRQTR

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. When Activated By Zras It Acts In Conjunction With Sigma-54 To Regulate The Expression Of Zrap. Positively Autoregulates The Expression Of The Zrasr Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=305, Percent_Identity=43.9344262295082, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789233, Length=464, Percent_Identity=34.2672413793103, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1788550, Length=306, Percent_Identity=41.1764705882353, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87082117, Length=255, Percent_Identity=49.0196078431373, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1790299, Length=328, Percent_Identity=41.4634146341463, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1788905, Length=331, Percent_Identity=37.7643504531722, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1789087, Length=263, Percent_Identity=44.106463878327, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=36.8098159509202, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=39.297124600639, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI87082152, Length=238, Percent_Identity=44.5378151260504, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87081872, Length=300, Percent_Identity=38.3333333333333, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081858, Length=461, Percent_Identity=25.5965292841649, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=31.6017316017316, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51926; Mature: 51794

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADHSQELLSKHVKRILDALPEGVFISDASGTSLRVNRMYEQLTGLTQEQVQGKNVRCLV
CCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHCCCHHHHCCCCEEEEE
EEGVFDHILNPQIVRTGRPATHVQQLKDGKKLVLTGFPVFDTRGDLCLVVTFARDITLLA
ECCHHHHHCCCCEEECCCCHHHHHHHCCCCEEEEECCCEECCCCCEEEEEEHHHHHHHHH
QLQDQVAGQCRLIDQINDQLAYMTSEGNKARDPIYASPAMGEVVSLLRRFAATDATVLIL
HHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
GETGAGKDVFARFTHGLSERRDKILLKVDCGGISETLTESELFGYMPGAFTGASSKGKAG
ECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
YFEIADGSTIFLDEVGELPLSMQTRLLRVLQDGEIMRVGASSPRKVDVRIIAATNRNLAE
EEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCHHH
SVEAGTFRRDLYYRLNVATVRIPSLRDRKEDVPLLAEHFLAHYAAKYHKVMAFMDVTLNM
HHHHCCHHEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAAYAWPGNVRELQNMVHSLVITLNGPLITPRDLPAQVTGVTHDASRYSEDVLVPRRPLR
HHHHCCCCCHHHHHHHHHHEEEEECCCEECCCCCCCCEECCCCCHHHHCCCCCCCHHHHH
EIMAEMERDFLLKAIEVHGSVQRVAELFQVNRSTIFRKLQGTRQTR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADHSQELLSKHVKRILDALPEGVFISDASGTSLRVNRMYEQLTGLTQEQVQGKNVRCLV
CCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHCCCHHHHCCCCEEEEE
EEGVFDHILNPQIVRTGRPATHVQQLKDGKKLVLTGFPVFDTRGDLCLVVTFARDITLLA
ECCHHHHHCCCCEEECCCCHHHHHHHCCCCEEEEECCCEECCCCCEEEEEEHHHHHHHHH
QLQDQVAGQCRLIDQINDQLAYMTSEGNKARDPIYASPAMGEVVSLLRRFAATDATVLIL
HHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
GETGAGKDVFARFTHGLSERRDKILLKVDCGGISETLTESELFGYMPGAFTGASSKGKAG
ECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
YFEIADGSTIFLDEVGELPLSMQTRLLRVLQDGEIMRVGASSPRKVDVRIIAATNRNLAE
EEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCHHH
SVEAGTFRRDLYYRLNVATVRIPSLRDRKEDVPLLAEHFLAHYAAKYHKVMAFMDVTLNM
HHHHCCHHEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAAYAWPGNVRELQNMVHSLVITLNGPLITPRDLPAQVTGVTHDASRYSEDVLVPRRPLR
HHHHCCCCCHHHHHHHHHHEEEEECCCEECCCCCCCCEECCCCCHHHHCCCCCCCHHHHH
EIMAEMERDFLLKAIEVHGSVQRVAELFQVNRSTIFRKLQGTRQTR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA