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The map label for this gene is dapB

Identifier: 220904692

GI number: 220904692

Start: 1703544

End: 1704323

Strand: Reverse

Name: dapB

Synonym: Ddes_1424

Alternate gene names: 220904692

Gene position: 1704323-1703544 (Counterclockwise)

Preceding gene: 220904693

Following gene: 220904689

Centisome position: 59.31

GC content: 59.87

Gene sequence:

>780_bases
ATGAGTACAGCCATCATCGTGGTAGGGGCCAACGGACGCATGGGCAAAACCATCAGCCATCTGGCGGCGACGGAGTCGGC
CTTCAGTCTGGCTGGCCTGGTAGATAGCAGGGAGCATGTGGAAAGCCTGGCAGGCGCATCCTGCCCCGTGGGCGACAGCC
TTGCCGCAGTGCTGCCCAAAGCGCCGGGCGCTGTGGCTATTGACTTTACTGCCCCCTCCGTAAGTTTGCAGTCGGCCCGT
GCCGTGGCCGCGAGCGGGCATGCCCTGGTTATCGGCACTACGGGCTTTACTGATGCGGAAAAGGACGAACTGCACGAGCT
GGCAAAAAAAGCTCCTATTTTCTGGGCATCCAACATGAGCATCGGCGTCAATGTGCTGTGCAAGATACTGCCGGAACTGA
CCCGCGCTCTGGGCGATGCATACGATATAGAAATGGTTGAGCTGCATCATAATCGCAAAAAAGACAGTCCCAGTGGCACG
GCCTTGACCCTTGGCGAATGCCTGGCTGAAGCCCGCGGCTGGCAGCTTAACGACGTGCGCTGCTCTGCCCGTGATGGTAT
TATCGGCGAACGGCCCAAAGCCCAGATCGGTATTCAGGCCATACGCGGCGGCGATGTGGTGGGCGTGCATACAGTGTACT
TTATGGGACCCGGCGAACGCATCGAAGTGACACATCAGGCCCATTCGCGTGATACCTTCGCCCAGGGCGCGCTGCGGGCG
GCTGCATGGCTGGTCGGGCAGAAGCCGGGCAAGCTTTACGGCATGCGTGATATGTTCTGA

Upstream 100 bases:

>100_bases
AGGCGCTGGGCGTAACGGTACTCACCGAAGAAGAATTTATGACCATGTTGCGCGAAGCCAAAGCGGCTTCGGAATAATTT
GAATACAAAGCGAGCAAAGC

Downstream 100 bases:

>100_bases
TTCCTTCAATTCCGGTCTTTTGCCCCAGCGCGCCGGTTGAAAGCCAGTGGACATACAATGTAAGAAACCCCTTCTCAGAC
CGTTGCTTGCGCAGCGGCTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSTAIIVVGANGRMGKTISHLAATESAFSLAGLVDSREHVESLAGASCPVGDSLAAVLPKAPGAVAIDFTAPSVSLQSAR
AVAASGHALVIGTTGFTDAEKDELHELAKKAPIFWASNMSIGVNVLCKILPELTRALGDAYDIEMVELHHNRKKDSPSGT
ALTLGECLAEARGWQLNDVRCSARDGIIGERPKAQIGIQAIRGGDVVGVHTVYFMGPGERIEVTHQAHSRDTFAQGALRA
AAWLVGQKPGKLYGMRDMF

Sequences:

>Translated_259_residues
MSTAIIVVGANGRMGKTISHLAATESAFSLAGLVDSREHVESLAGASCPVGDSLAAVLPKAPGAVAIDFTAPSVSLQSAR
AVAASGHALVIGTTGFTDAEKDELHELAKKAPIFWASNMSIGVNVLCKILPELTRALGDAYDIEMVELHHNRKKDSPSGT
ALTLGECLAEARGWQLNDVRCSARDGIIGERPKAQIGIQAIRGGDVVGVHTVYFMGPGERIEVTHQAHSRDTFAQGALRA
AAWLVGQKPGKLYGMRDMF
>Mature_258_residues
STAIIVVGANGRMGKTISHLAATESAFSLAGLVDSREHVESLAGASCPVGDSLAAVLPKAPGAVAIDFTAPSVSLQSARA
VAASGHALVIGTTGFTDAEKDELHELAKKAPIFWASNMSIGVNVLCKILPELTRALGDAYDIEMVELHHNRKKDSPSGTA
LTLGECLAEARGWQLNDVRCSARDGIIGERPKAQIGIQAIRGGDVVGVHTVYFMGPGERIEVTHQAHSRDTFAQGALRAA
AWLVGQKPGKLYGMRDMF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=40.530303030303, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_DESDA (B8J0P9)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480004.1
- GeneID:   7285120
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1424
- HOGENOM:   HBG594002
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27222; Mature: 27091

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAIIVVGANGRMGKTISHLAATESAFSLAGLVDSREHVESLAGASCPVGDSLAAVLPK
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHCCC
APGAVAIDFTAPSVSLQSARAVAASGHALVIGTTGFTDAEKDELHELAKKAPIFWASNMS
CCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCEEEECCCC
IGVNVLCKILPELTRALGDAYDIEMVELHHNRKKDSPSGTALTLGECLAEARGWQLNDVR
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCEECCEE
CSARDGIIGERPKAQIGIQAIRGGDVVGVHTVYFMGPGERIEVTHQAHSRDTFAQGALRA
ECCCCCCCCCCCCHHCCEEEECCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHH
AAWLVGQKPGKLYGMRDMF
HHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure 
STAIIVVGANGRMGKTISHLAATESAFSLAGLVDSREHVESLAGASCPVGDSLAAVLPK
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHCCC
APGAVAIDFTAPSVSLQSARAVAASGHALVIGTTGFTDAEKDELHELAKKAPIFWASNMS
CCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCEEEECCCC
IGVNVLCKILPELTRALGDAYDIEMVELHHNRKKDSPSGTALTLGECLAEARGWQLNDVR
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCEECCEE
CSARDGIIGERPKAQIGIQAIRGGDVVGVHTVYFMGPGERIEVTHQAHSRDTFAQGALRA
ECCCCCCCCCCCCHHCCEEEECCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHH
AAWLVGQKPGKLYGMRDMF
HHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA