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The map label for this gene is uppP

Identifier: 220904686

GI number: 220904686

Start: 1696571

End: 1697368

Strand: Reverse

Name: uppP

Synonym: Ddes_1418

Alternate gene names: 220904686

Gene position: 1697368-1696571 (Counterclockwise)

Preceding gene: 220904688

Following gene: 220904681

Centisome position: 59.07

GC content: 53.13

Gene sequence:

>798_bases
ATGGACAATTTGCTCACAGCGTTGATATTGAGCATAGTTGAAGGGTTAACAGAATTCTTGCCGGTCTCGTCGTCCGGCCA
TCTCATTCTTGCCGGAGATCTGCTCGGTTTTGTGGGGGAAAAAGCCGCCACCTTTGATGTCGTCATCCAGCTTGGCGCCA
TCATGGCTGTGGTGGTTCTCTACTGGAAGCGCTTCTGGGGCCTTGTGCGGCCACAGCCGTATGCCCGCTTTGCCGGCAGA
CGCGGCATCGTTCTGCTCATGCTTACTTCGCTGCCCGCATGCATTCTGGGCCTGCTGCTGCACGCCTACATCAAGGAATA
TCTGTTTCGCCCGGCGACAGTGCTTATCGCTCTTGTGGTGGGGGCCATCTGCATGATTCTTGTGGAAAAACGCAAATTCA
AGCCCACCTGCATCAGCCTTGATGACATGACACCACGTCTGGCTCTGGGCATTGGCTGCTTTCAGTGCCTGGCCCTCTGG
CCGGGCTTTTCACGTTCGGCGGCCACCATTATGGGAGGCATGCTGCTGGGAGCCAAAAGGCCTTTGGCAGCGGAATATTC
CTTTATTGCGGCCGTGCCGATTATGGTTGCCGCCACTGGATACGACCTGCTGAAAAATCTGAGTATGTTCACCGCTGCGG
ATATTCCCTTTTTTCTGGTAGGCATGATTGGTTCTTTTGTGTCTGCCCTTTTGGCGGTAAAGGTTTTTGTGGCCCTGGTG
GGACGGATGACACTGATTCCTTTTGCCTGCTATCGTTTGCTGATAGCGCCTTTTGTATATTATTTTATGGTGAATTGA

Upstream 100 bases:

>100_bases
TCTTTTGGCAACGGCTGAACTTCGCGAGCTTGTGTTCCGGCTGGCGAAGCAGCCGGGCAAACAGCAACTCGCCACACGGC
ACCCATATACGAGGCCAGTT

Downstream 100 bases:

>100_bases
CCGGCAGGTATCCCCCCAAAAAAATATTGTTTTGCGCCCGACGGGTGAAAAAATGCTGTGTGAGGCAGGGCATCTTGTAA
AAATTGTGTACCGTGGGTGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDNLLTALILSIVEGLTEFLPVSSSGHLILAGDLLGFVGEKAATFDVVIQLGAIMAVVVLYWKRFWGLVRPQPYARFAGR
RGIVLLMLTSLPACILGLLLHAYIKEYLFRPATVLIALVVGAICMILVEKRKFKPTCISLDDMTPRLALGIGCFQCLALW
PGFSRSAATIMGGMLLGAKRPLAAEYSFIAAVPIMVAATGYDLLKNLSMFTAADIPFFLVGMIGSFVSALLAVKVFVALV
GRMTLIPFACYRLLIAPFVYYFMVN

Sequences:

>Translated_265_residues
MDNLLTALILSIVEGLTEFLPVSSSGHLILAGDLLGFVGEKAATFDVVIQLGAIMAVVVLYWKRFWGLVRPQPYARFAGR
RGIVLLMLTSLPACILGLLLHAYIKEYLFRPATVLIALVVGAICMILVEKRKFKPTCISLDDMTPRLALGIGCFQCLALW
PGFSRSAATIMGGMLLGAKRPLAAEYSFIAAVPIMVAATGYDLLKNLSMFTAADIPFFLVGMIGSFVSALLAVKVFVALV
GRMTLIPFACYRLLIAPFVYYFMVN
>Mature_265_residues
MDNLLTALILSIVEGLTEFLPVSSSGHLILAGDLLGFVGEKAATFDVVIQLGAIMAVVVLYWKRFWGLVRPQPYARFAGR
RGIVLLMLTSLPACILGLLLHAYIKEYLFRPATVLIALVVGAICMILVEKRKFKPTCISLDDMTPRLALGIGCFQCLALW
PGFSRSAATIMGGMLLGAKRPLAAEYSFIAAVPIMVAATGYDLLKNLSMFTAADIPFFLVGMIGSFVSALLAVKVFVALV
GRMTLIPFACYRLLIAPFVYYFMVN

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=267, Percent_Identity=54.3071161048689, Blast_Score=266, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_DESDA (B8J0P3)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479998.1
- GeneID:   7285114
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1418
- HOGENOM:   HBG391969
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28826; Mature: 28826

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x273fd4c4)-; HASH(0x40516288)-; HASH(0x279bd794)-; HASH(0x40565674)-; HASH(0x2786b4dc)-; HASH(0x2786b7ac)-; HASH(0x404f3410)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLLTALILSIVEGLTEFLPVSSSGHLILAGDLLGFVGEKAATFDVVIQLGAIMAVVVL
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YWKRFWGLVRPQPYARFAGRRGIVLLMLTSLPACILGLLLHAYIKEYLFRPATVLIALVV
HHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
GAICMILVEKRKFKPTCISLDDMTPRLALGIGCFQCLALWPGFSRSAATIMGGMLLGAKR
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
PLAAEYSFIAAVPIMVAATGYDLLKNLSMFTAADIPFFLVGMIGSFVSALLAVKVFVALV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRMTLIPFACYRLLIAPFVYYFMVN
HHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDNLLTALILSIVEGLTEFLPVSSSGHLILAGDLLGFVGEKAATFDVVIQLGAIMAVVVL
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YWKRFWGLVRPQPYARFAGRRGIVLLMLTSLPACILGLLLHAYIKEYLFRPATVLIALVV
HHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
GAICMILVEKRKFKPTCISLDDMTPRLALGIGCFQCLALWPGFSRSAATIMGGMLLGAKR
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
PLAAEYSFIAAVPIMVAATGYDLLKNLSMFTAADIPFFLVGMIGSFVSALLAVKVFVALV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRMTLIPFACYRLLIAPFVYYFMVN
HHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA