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The map label for this gene is pyrF [H]

Identifier: 220904675

GI number: 220904675

Start: 1682039

End: 1682746

Strand: Direct

Name: pyrF [H]

Synonym: Ddes_1407

Alternate gene names: 220904675

Gene position: 1682039-1682746 (Clockwise)

Preceding gene: 220904674

Following gene: 220904676

Centisome position: 58.54

GC content: 62.71

Gene sequence:

>708_bases
ATGAAAAGCGCAAATATCGCTCCACAGCTTATGGTGGCGCTTGATGTGCCGAGCAGAGAGGAAACCCTCGCCCTTGCCCG
CACACTGGCAGGAACCGCGCCCTGGTGCAAGGTGGGCATGGAGATGTTCACCCACGCCGGGCCGCCCCTGCTTGAAGAGC
TGGCCGCTCTGGGCTACAGTATCTTTCTGGATCTCAAATTCTACGACATACCGCACACGGTGGCCCAGGCAGTCAAGGCG
GCTTCGGGCGTAGGCGTAAACATGCTCACCCTGCACTGTCAGGGCGGCGAACGCATGTGCCGTGCCGCGCGCGAGGCTGT
CTGCAGCTTGCCCGGCAAAGGCCCGCTACTTTTCGGCGTTACCGTGCTGACAAGCTTTGCCCGGGGCGAAATGCCCGGTA
TCAGCGCCGACCTGCCGGACTTTGCCCGCACCCTCGCCACAAATGCACAGAGCTGGGGGCTGGACGGCGTGGTCTGTTCC
GGTCATGAGGCTGCGGATATCAAGGCTGCCTGCCCCTCCCTCATGTGCCTTTGCCCCGGCATCCGCCCCGCGGGTTCGGT
GGCGGATGATCAGCGCCGTGTCATGACTCCTGCGCAGGCTGTAGCCGCAGGGGCAGACTATCTTGTAGTGGGCAGACCCA
TTATCGCCGCTCCTGATCCGCTTATGGCGGCAAAGCAGATTCTGGCGGAGATGGCTTCCGCCACATAA

Upstream 100 bases:

>100_bases
TGTCGGAAACAGTGCTGCGCGGCTGAGCCGCTGCCGTACGGCAGCCATACCAGTACAGCAGGTACCTTTACTTTATTGAC
GCCACGAACCGGATTAAATC

Downstream 100 bases:

>100_bases
CGAACGAGGATTTTCATGTCCGGCCAAAAGACCACGGAAAACACGCGCCCTGCGGCGCACGCGCAAACCGCTACGGCCCC
CAAGGCCGAGGTGCGCGGCG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKSANIAPQLMVALDVPSREETLALARTLAGTAPWCKVGMEMFTHAGPPLLEELAALGYSIFLDLKFYDIPHTVAQAVKA
ASGVGVNMLTLHCQGGERMCRAAREAVCSLPGKGPLLFGVTVLTSFARGEMPGISADLPDFARTLATNAQSWGLDGVVCS
GHEAADIKAACPSLMCLCPGIRPAGSVADDQRRVMTPAQAVAAGADYLVVGRPIIAAPDPLMAAKQILAEMASAT

Sequences:

>Translated_235_residues
MKSANIAPQLMVALDVPSREETLALARTLAGTAPWCKVGMEMFTHAGPPLLEELAALGYSIFLDLKFYDIPHTVAQAVKA
ASGVGVNMLTLHCQGGERMCRAAREAVCSLPGKGPLLFGVTVLTSFARGEMPGISADLPDFARTLATNAQSWGLDGVVCS
GHEAADIKAACPSLMCLCPGIRPAGSVADDQRRVMTPAQAVAAGADYLVVGRPIIAAPDPLMAAKQILAEMASAT
>Mature_235_residues
MKSANIAPQLMVALDVPSREETLALARTLAGTAPWCKVGMEMFTHAGPPLLEELAALGYSIFLDLKFYDIPHTVAQAVKA
ASGVGVNMLTLHCQGGERMCRAAREAVCSLPGKGPLLFGVTVLTSFARGEMPGISADLPDFARTLATNAQSWGLDGVVCS
GHEAADIKAACPSLMCLCPGIRPAGSVADDQRRVMTPAQAVAAGADYLVVGRPIIAAPDPLMAAKQILAEMASAT

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=225, Percent_Identity=46.2222222222222, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 24418; Mature: 24418

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSANIAPQLMVALDVPSREETLALARTLAGTAPWCKVGMEMFTHAGPPLLEELAALGYS
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCEE
IFLDLKFYDIPHTVAQAVKAASGVGVNMLTLHCQGGERMCRAAREAVCSLPGKGPLLFGV
EEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHH
TVLTSFARGEMPGISADLPDFARTLATNAQSWGLDGVVCSGHEAADIKAACPSLMCLCPG
HHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCC
IRPAGSVADDQRRVMTPAQAVAAGADYLVVGRPIIAAPDPLMAAKQILAEMASAT
CCCCCCCCCCHHHHCCHHHHHHCCCCEEEECCCEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSANIAPQLMVALDVPSREETLALARTLAGTAPWCKVGMEMFTHAGPPLLEELAALGYS
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCEE
IFLDLKFYDIPHTVAQAVKAASGVGVNMLTLHCQGGERMCRAAREAVCSLPGKGPLLFGV
EEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHH
TVLTSFARGEMPGISADLPDFARTLATNAQSWGLDGVVCSGHEAADIKAACPSLMCLCPG
HHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCC
IRPAGSVADDQRRVMTPAQAVAAGADYLVVGRPIIAAPDPLMAAKQILAEMASAT
CCCCCCCCCCHHHHCCHHHHHHCCCCEEEECCCEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA