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The map label for this gene is apbE [H]

Identifier: 220904513

GI number: 220904513

Start: 1458170

End: 1459213

Strand: Direct

Name: apbE [H]

Synonym: Ddes_1244

Alternate gene names: 220904513

Gene position: 1458170-1459213 (Clockwise)

Preceding gene: 220904512

Following gene: 220904514

Centisome position: 50.75

GC content: 58.72

Gene sequence:

>1044_bases
ATGTCCAGCTTTTTGAGCCGCCGTCATTTTCTTCGCTTCGCGCTTGTGAGCGCGGGCATGCTTGGGGCCGCCCCGCTGCT
GAGTCTTGCGCCCTCCGCCACGTTGGCGCGGACGTCCGGCAGTGAAGAAACCTACACCAGAACTGCCCTGTTTATGGGAA
CCATGGTCACAGTTACCGTGGCAGGAACTACTCCGGAACAGGCTGGGGAGGCTGTGAGCACCGCCTTGGCCCTTGGCCGC
GACATGGCCGGCACGCTGACCCGGTTCAATACCAGTGCCCCTTTGGGGCAGCTTAATGCAAGTACCGCCTTGAACGATGC
CCCTCCCGCACTTGTGCACCTGATGCAGCGTTCACAGCAGATGCATGCTCTCACAGGCGGCGCTTTTGACCCGACCGTTC
TCCCCCTTTTGCATCTTCTTGAAAGCCACCGTGACCATAAAGCGCAAAAACACCTTCAGCTTGATCAAGCGGAGGTGCGC
GATGCCCTTGAAATGGTGGGAATGGAGCGGGTGCATGCAGACGGATATGCCTTGCGCCTTGAGCGGCAGGGCATGGGCAT
CACCCTGGACGGTATTGCTAAGGGACATATTGCAGACCTCATGTCGCGCAGTCTCAGCTCTGCGGGATACCCCAATCATT
GCGTCAACGCCGGCGGAGATATTGCGGTCAGCGGAAGCAAGCTCAAGGGACAACCCTGGCGCATAGCTATTGAAGATCCC
TACGGCAAAAATGCCTATCCACAAGTGGTGGAAGCATACAGCGGGGCCGTAGCCACTTCGGGCATATATGAGATTTTTTA
CAATGCCGATGCCAGCCGTAACCATCTGGTTAATCCTGTAACGGGAGCCAGCGCTGGTTTGGCCAGCGTGACGGTTACCG
CTCCCGACTGCCTCACGGCCGATGCGCTTGCCACAGCCATGGCTATCATGCCCCCGAGAGAAGCTCTTCATTTGGCCGAC
AGCCTGTCGGGCTGCGCCTGCTGTCTGTTGCGCCATGACGGACTGACACAGTGTTCCCGCAATTGGCGGGGGCGTAGCGC
ATAA

Upstream 100 bases:

>100_bases
ACGAGTCAGGCTGCAGTGAGCCGGCGCACACACCCCTTTCGGCTCCTGTACCTGATCAGAACGTCTCCCAGGCGCAGCCT
GGGGCCTGAATGGAGGCAAT

Downstream 100 bases:

>100_bases
GCACTGCGGATATTTGTTCTTCATGCATCTGTCGCATGCAGATAGATGCATTTTGGCACTCAAATTTACCCTGAAAATTT
TTCTCTCGACAAGGTACAGA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSSFLSRRHFLRFALVSAGMLGAAPLLSLAPSATLARTSGSEETYTRTALFMGTMVTVTVAGTTPEQAGEAVSTALALGR
DMAGTLTRFNTSAPLGQLNASTALNDAPPALVHLMQRSQQMHALTGGAFDPTVLPLLHLLESHRDHKAQKHLQLDQAEVR
DALEMVGMERVHADGYALRLERQGMGITLDGIAKGHIADLMSRSLSSAGYPNHCVNAGGDIAVSGSKLKGQPWRIAIEDP
YGKNAYPQVVEAYSGAVATSGIYEIFYNADASRNHLVNPVTGASAGLASVTVTAPDCLTADALATAMAIMPPREALHLAD
SLSGCACCLLRHDGLTQCSRNWRGRSA

Sequences:

>Translated_347_residues
MSSFLSRRHFLRFALVSAGMLGAAPLLSLAPSATLARTSGSEETYTRTALFMGTMVTVTVAGTTPEQAGEAVSTALALGR
DMAGTLTRFNTSAPLGQLNASTALNDAPPALVHLMQRSQQMHALTGGAFDPTVLPLLHLLESHRDHKAQKHLQLDQAEVR
DALEMVGMERVHADGYALRLERQGMGITLDGIAKGHIADLMSRSLSSAGYPNHCVNAGGDIAVSGSKLKGQPWRIAIEDP
YGKNAYPQVVEAYSGAVATSGIYEIFYNADASRNHLVNPVTGASAGLASVTVTAPDCLTADALATAMAIMPPREALHLAD
SLSGCACCLLRHDGLTQCSRNWRGRSA
>Mature_346_residues
SSFLSRRHFLRFALVSAGMLGAAPLLSLAPSATLARTSGSEETYTRTALFMGTMVTVTVAGTTPEQAGEAVSTALALGRD
MAGTLTRFNTSAPLGQLNASTALNDAPPALVHLMQRSQQMHALTGGAFDPTVLPLLHLLESHRDHKAQKHLQLDQAEVRD
ALEMVGMERVHADGYALRLERQGMGITLDGIAKGHIADLMSRSLSSAGYPNHCVNAGGDIAVSGSKLKGQPWRIAIEDPY
GKNAYPQVVEAYSGAVATSGIYEIFYNADASRNHLVNPVTGASAGLASVTVTAPDCLTADALATAMAIMPPREALHLADS
LSGCACCLLRHDGLTQCSRNWRGRSA

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=339, Percent_Identity=26.8436578171091, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36592; Mature: 36461

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFLSRRHFLRFALVSAGMLGAAPLLSLAPSATLARTSGSEETYTRTALFMGTMVTVTV
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCEEEEEEE
AGTTPEQAGEAVSTALALGRDMAGTLTRFNTSAPLGQLNASTALNDAPPALVHLMQRSQQ
ECCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
MHALTGGAFDPTVLPLLHLLESHRDHKAQKHLQLDQAEVRDALEMVGMERVHADGYALRL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEE
ERQGMGITLDGIAKGHIADLMSRSLSSAGYPNHCVNAGGDIAVSGSKLKGQPWRIAIEDP
ECCCCCEEECCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCEEEEEECC
YGKNAYPQVVEAYSGAVATSGIYEIFYNADASRNHLVNPVTGASAGLASVTVTAPDCLTA
CCCCCHHHHHHHHCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHH
DALATAMAIMPPREALHLADSLSGCACCLLRHDGLTQCSRNWRGRSA
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SSFLSRRHFLRFALVSAGMLGAAPLLSLAPSATLARTSGSEETYTRTALFMGTMVTVTV
CHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCEEEEEEE
AGTTPEQAGEAVSTALALGRDMAGTLTRFNTSAPLGQLNASTALNDAPPALVHLMQRSQQ
ECCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
MHALTGGAFDPTVLPLLHLLESHRDHKAQKHLQLDQAEVRDALEMVGMERVHADGYALRL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEE
ERQGMGITLDGIAKGHIADLMSRSLSSAGYPNHCVNAGGDIAVSGSKLKGQPWRIAIEDP
ECCCCCEEECCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCEEEEEECC
YGKNAYPQVVEAYSGAVATSGIYEIFYNADASRNHLVNPVTGASAGLASVTVTAPDCLTA
CCCCCHHHHHHHHCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHH
DALATAMAIMPPREALHLADSLSGCACCLLRHDGLTQCSRNWRGRSA
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]