Click here to switch to the map view.

The map label for this gene is fieF [H]

Identifier: 220904472

GI number: 220904472

Start: 1413186

End: 1414652

Strand: Direct

Name: fieF [H]

Synonym: Ddes_1202

Alternate gene names: 220904472

Gene position: 1413186-1414652 (Clockwise)

Preceding gene: 220904471

Following gene: 220904474

Centisome position: 49.18

GC content: 56.1

Gene sequence:

>1467_bases
ATGTCCAGTTCGCTGGAAGCCAGTGCTGAAAAAAATCGTGCGGCGCTTACATCATTGTGGGCGGCCTTTGCCCTTACTGC
CGTCAAGCTTGCTGTAGGGCTGCACACAAACAGCCTGGGCATTTTGTCTGAAGCACTTCACAGTGGCCTTGATTTGCTGG
CGGCAGCCATGACTCTTGCTGCCGTGCGTGTGGCATCCAGACCCGCAGACGCGCGACATCCCTACGGTCACGGCAAGATA
GAAAACCTTTCGGCGCTGGCCCAGACGCTGTTGCTGTTTTTGACCTGTTTTTGGGTCGTCCACGAAGGCGTGCAGCGCCT
CTTGGCTGGTGCAAGCCCCGTAACGCCTTCTTTGTGGGGCGTTGGGGTTATGGCTCTTTCTATCGTTATTGATGTCAACA
GGGTCCGCGTGCTGCGCCGTGTGGCAAAAAAATATAAAAGCCAAGCGCTTGAGGCTGATGCATTACACTTTTCCACTGAT
ATTCTTTCTTCAGCGGTGGTTCTTGTTGGTGTTCTTGCCGTATGGCTGGCTTCTGCCCTCAATGTTCCGGGGCCGATGCA
TGCGGTACTGGTTCAGGCTGATACGGTAGCCGCCCTGCTTGTCGCCGTTATCATTTTTCGCGCCAGCATTCGCATGGCTC
GTCAGGCTGTCGATATCCTTATGGACTCCGGCTCCATGCGCGAGCAGCAGGCCATTATAAAGGTTGTCGGCCGGGTGCCT
GGCATTACGAATGTTCGCGATGTGCGCCTGCGCACCAGCGGTCCCACCAGTTTTGTGGATCTGACTGTAGGGGTAGAGCC
GGGCATACAGGTCAGCGAAGGGCATAAGCTGGCCCATGAGGCGGAAGAGGCCGTGGCTTCAGTGCTGGAAGGCGCGGACG
TGACCGTCCATGTAGAGCCGCATAGTGCCGAGGATGACAGACACTGTGATCCATTCGTGCAGGTGCAGCACACCGCCTGG
AAGCATGCCCTGGCTGTGCATAACGTGCACATCCTGCGTTCGGCTGGTAACTGTTTTGTTGAATTGCATGTAGAGCTTCC
CGGCAAGATGCCCTTTGTGCAGGCATATGGCCGGGTGGTGGATTTTGAAGACGATCTGCGCAAAACCATGCCCGGCAGCG
AGGTTGTGAGTCATCTTGAGCCGGTGGGCACTGCTTACGCGCTGGCGTATGGGGCTTCTGTATCGGTACCGTATGCCGAG
ATGGTTTGGCGTGAAATAGAAGCTGTGCTTGCAAAAGAGCCGTTGGCCTGTAACCCGCACAAGTTTTCGACCTACGAATT
GCCGGAGCAGGGCGTTTGCATTTCTTTCCACTGCGATGTGGACGCCACGTTGAGCGTTGAAGAGGCGCATACCGTATGCA
TGCGCCTGGAAAAACAATTACGTCTGAGCGCCCCGCAGTTGGGCCGTATCATTATTCATATGGAGCCGGGAGCACGCCCC
CAAAGGGAGCAGGGTAGCGTCATATAG

Upstream 100 bases:

>100_bases
GGCAGAAACGTCAAGGGTCCTGGCGTGAATGGTTCAAATGGCTATAGGAACTTAAAGATAAAAGCCCCTCCGGGGGCTTT
TTTTACTCGTGGGGTCTGTT

Downstream 100 bases:

>100_bases
GGCGACCATCTGCCTACTGTGCATTTTCTGCCGATGGTATTATGGTAACTCCGGCGGCCCGGGCCAGTTCCTGCCACAGG
CGATCAATGCCCAGACGGCT

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MSSSLEASAEKNRAALTSLWAAFALTAVKLAVGLHTNSLGILSEALHSGLDLLAAAMTLAAVRVASRPADARHPYGHGKI
ENLSALAQTLLLFLTCFWVVHEGVQRLLAGASPVTPSLWGVGVMALSIVIDVNRVRVLRRVAKKYKSQALEADALHFSTD
ILSSAVVLVGVLAVWLASALNVPGPMHAVLVQADTVAALLVAVIIFRASIRMARQAVDILMDSGSMREQQAIIKVVGRVP
GITNVRDVRLRTSGPTSFVDLTVGVEPGIQVSEGHKLAHEAEEAVASVLEGADVTVHVEPHSAEDDRHCDPFVQVQHTAW
KHALAVHNVHILRSAGNCFVELHVELPGKMPFVQAYGRVVDFEDDLRKTMPGSEVVSHLEPVGTAYALAYGASVSVPYAE
MVWREIEAVLAKEPLACNPHKFSTYELPEQGVCISFHCDVDATLSVEEAHTVCMRLEKQLRLSAPQLGRIIIHMEPGARP
QREQGSVI

Sequences:

>Translated_488_residues
MSSSLEASAEKNRAALTSLWAAFALTAVKLAVGLHTNSLGILSEALHSGLDLLAAAMTLAAVRVASRPADARHPYGHGKI
ENLSALAQTLLLFLTCFWVVHEGVQRLLAGASPVTPSLWGVGVMALSIVIDVNRVRVLRRVAKKYKSQALEADALHFSTD
ILSSAVVLVGVLAVWLASALNVPGPMHAVLVQADTVAALLVAVIIFRASIRMARQAVDILMDSGSMREQQAIIKVVGRVP
GITNVRDVRLRTSGPTSFVDLTVGVEPGIQVSEGHKLAHEAEEAVASVLEGADVTVHVEPHSAEDDRHCDPFVQVQHTAW
KHALAVHNVHILRSAGNCFVELHVELPGKMPFVQAYGRVVDFEDDLRKTMPGSEVVSHLEPVGTAYALAYGASVSVPYAE
MVWREIEAVLAKEPLACNPHKFSTYELPEQGVCISFHCDVDATLSVEEAHTVCMRLEKQLRLSAPQLGRIIIHMEPGARP
QREQGSVI
>Mature_487_residues
SSSLEASAEKNRAALTSLWAAFALTAVKLAVGLHTNSLGILSEALHSGLDLLAAAMTLAAVRVASRPADARHPYGHGKIE
NLSALAQTLLLFLTCFWVVHEGVQRLLAGASPVTPSLWGVGVMALSIVIDVNRVRVLRRVAKKYKSQALEADALHFSTDI
LSSAVVLVGVLAVWLASALNVPGPMHAVLVQADTVAALLVAVIIFRASIRMARQAVDILMDSGSMREQQAIIKVVGRVPG
ITNVRDVRLRTSGPTSFVDLTVGVEPGIQVSEGHKLAHEAEEAVASVLEGADVTVHVEPHSAEDDRHCDPFVQVQHTAWK
HALAVHNVHILRSAGNCFVELHVELPGKMPFVQAYGRVVDFEDDLRKTMPGSEVVSHLEPVGTAYALAYGASVSVPYAEM
VWREIEAVLAKEPLACNPHKFSTYELPEQGVCISFHCDVDATLSVEEAHTVCMRLEKQLRLSAPQLGRIIIHMEPGARPQ
REQGSVI

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=279, Percent_Identity=30.4659498207885, Blast_Score=141, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 52581; Mature: 52450

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSLEASAEKNRAALTSLWAAFALTAVKLAVGLHTNSLGILSEALHSGLDLLAAAMTLA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVRVASRPADARHPYGHGKIENLSALAQTLLLFLTCFWVVHEGVQRLLAGASPVTPSLWG
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VGVMALSIVIDVNRVRVLRRVAKKYKSQALEADALHFSTDILSSAVVLVGVLAVWLASAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVPGPMHAVLVQADTVAALLVAVIIFRASIRMARQAVDILMDSGSMREQQAIIKVVGRVP
CCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GITNVRDVRLRTSGPTSFVDLTVGVEPGIQVSEGHKLAHEAEEAVASVLEGADVTVHVEP
CCCCCEEEEEECCCCCEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEEECC
HSAEDDRHCDPFVQVQHTAWKHALAVHNVHILRSAGNCFVELHVELPGKMPFVQAYGRVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCCCHHHHHHCCCC
DFEDDLRKTMPGSEVVSHLEPVGTAYALAYGASVSVPYAEMVWREIEAVLAKEPLACNPH
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
KFSTYELPEQGVCISFHCDVDATLSVEEAHTVCMRLEKQLRLSAPQLGRIIIHMEPGARP
CCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
QREQGSVI
CCCCCCCC
>Mature Secondary Structure 
SSSLEASAEKNRAALTSLWAAFALTAVKLAVGLHTNSLGILSEALHSGLDLLAAAMTLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVRVASRPADARHPYGHGKIENLSALAQTLLLFLTCFWVVHEGVQRLLAGASPVTPSLWG
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VGVMALSIVIDVNRVRVLRRVAKKYKSQALEADALHFSTDILSSAVVLVGVLAVWLASAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVPGPMHAVLVQADTVAALLVAVIIFRASIRMARQAVDILMDSGSMREQQAIIKVVGRVP
CCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GITNVRDVRLRTSGPTSFVDLTVGVEPGIQVSEGHKLAHEAEEAVASVLEGADVTVHVEP
CCCCCEEEEEECCCCCEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEEECC
HSAEDDRHCDPFVQVQHTAWKHALAVHNVHILRSAGNCFVELHVELPGKMPFVQAYGRVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCCCHHHHHHCCCC
DFEDDLRKTMPGSEVVSHLEPVGTAYALAYGASVSVPYAEMVWREIEAVLAKEPLACNPH
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
KFSTYELPEQGVCISFHCDVDATLSVEEAHTVCMRLEKQLRLSAPQLGRIIIHMEPGARP
CCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
QREQGSVI
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA