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The map label for this gene is ydeL [H]

Identifier: 220904432

GI number: 220904432

Start: 1369907

End: 1371346

Strand: Reverse

Name: ydeL [H]

Synonym: Ddes_1162

Alternate gene names: 220904432

Gene position: 1371346-1369907 (Counterclockwise)

Preceding gene: 220904437

Following gene: 220904431

Centisome position: 47.72

GC content: 50.97

Gene sequence:

>1440_bases
ATGCTATATCTGAATGCTGCCGGTAAAATCCCCCTCTATCAACAGCTTTATGAGCAGATAAAAAAAGAAATTCTTGCAGG
AATAAGGAGCGCTGACGCCGGGTTGCCCTCCATACGCACCATGGCAAAAGAACTGCAGCTTGGCAAAAATACGGTTGAGA
ATGCCTATGCCCAGCTTGTTCTTGAGGGCTATGTACGCGTACGCCCTGGCAGCGGATACAGGGTGAATCGCGTATACAGC
CACATGAATGCGGCCGAGCTACCCCATGTCAACACCGGTATGGTCATGTCGGACGAAAAAAAAACGACACCACAGAAACA
CATCGACTACGATTTCAATTACGAAAATCTGGATGCTTCAATTTTCCCCGCCGCCATATGGCGCAGGTTGATGGCCGACA
TTCTGTCGTCTCTTCATAAAAACAGCCGTCAGGCGGTGGATATGCATGCGTACGGAGATGCCTGTGGCAGTTTTTCCCTG
CGCAGCGAACTGGTTTCCTATCTTTATCGTAGCCGCGGAGTCTGCTGCACCCCTGAGCAGGTGATCATATGCAGCGGCCT
GCAGCCCGCAATCATTGCCGTCATGTGCCTGCTTCAAGAGAAATGCGCTCTTGTTGCCATGGAAGATCCCGGCTATGCAG
GAGCCAGGGCAGCCTATGAACTTTTCAATGCAGACATACTTTCTGTCCCTGTAAAGAGCGATGGCATTGACATCGAAAAC
CTTGCGGCATCATCTGCCGGACTTGTTCATATTGCACCTTCGCACCAGTTTCCCACAGGGGTCGTCATGCCCATTTGCAG
ACGCATAAAGCTTCTGGAATGGGCCGCAAAAAATGACGGATTTATAATCGAAGATGATTATGACAGCGAGCTGCGCTATC
ACGGCAGGCCCATCCCCTCGCTACAGTCCATTGATGAAAACGGCCGTGTCATTTATATGGGAACATTTTCAAAAGTGCTT
TCTCCGGGTATGCGCATGTCTTATATGGTGCTGCCGCCCCTGCTTGCCGCCAGATTCAGCTCCGTTTTTTCGGACTTCCA
GTGCACTGTCCCCTGGCTTGAGCAGGCGGTTTTGAGCAGTTTCATAAAACAGGGGCACTGGGAAAAACATTTAAGAAAAA
TCTGCCTGCTCAAGAAAAAAAAGCATGACCTCTTTGTACACACCGTTGACCGCCTGTTTGGCAAACGCGTACGCATACAC
GGGCATAATGCCGGCCTGCACCTTTTATTGGAATTTCCTGCAGGTCCGGACGAAGCAAGCCTTGTGGCAAAGGCCGCCAC
TTGCGGTGTACGTGTATACCCAGCCTCGCCTTTCTGGCGAAACAGGGAACACAGCCCCGCCAACTGTCTGTTCCTGGGCT
ACGGCACGTTGACTGAGCCGGATATCATAACTGCCTTGGAACGGCTTGAAAAAGTATGGTTTTGCCCTGAAGGCATATAG

Upstream 100 bases:

>100_bases
ATTTTTTTTAACCTGACGCTTCAAGCCGGTTCAATCAGTGAGCCAGTCCACATCTTCAGACTTTCGTAAGGTGCGGCACG
TACGCATCGTGGGAAAAAGT

Downstream 100 bases:

>100_bases
GAATTGCATCTTGAAAACAGATAAGACGGATGCGTATGCCTGTGTTATATCGCCATCGATGAGGTTTTTCATGAAAAGAC
TTTCAGAGGCGACCATGTGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MLYLNAAGKIPLYQQLYEQIKKEILAGIRSADAGLPSIRTMAKELQLGKNTVENAYAQLVLEGYVRVRPGSGYRVNRVYS
HMNAAELPHVNTGMVMSDEKKTTPQKHIDYDFNYENLDASIFPAAIWRRLMADILSSLHKNSRQAVDMHAYGDACGSFSL
RSELVSYLYRSRGVCCTPEQVIICSGLQPAIIAVMCLLQEKCALVAMEDPGYAGARAAYELFNADILSVPVKSDGIDIEN
LAASSAGLVHIAPSHQFPTGVVMPICRRIKLLEWAAKNDGFIIEDDYDSELRYHGRPIPSLQSIDENGRVIYMGTFSKVL
SPGMRMSYMVLPPLLAARFSSVFSDFQCTVPWLEQAVLSSFIKQGHWEKHLRKICLLKKKKHDLFVHTVDRLFGKRVRIH
GHNAGLHLLLEFPAGPDEASLVAKAATCGVRVYPASPFWRNREHSPANCLFLGYGTLTEPDIITALERLEKVWFCPEGI

Sequences:

>Translated_479_residues
MLYLNAAGKIPLYQQLYEQIKKEILAGIRSADAGLPSIRTMAKELQLGKNTVENAYAQLVLEGYVRVRPGSGYRVNRVYS
HMNAAELPHVNTGMVMSDEKKTTPQKHIDYDFNYENLDASIFPAAIWRRLMADILSSLHKNSRQAVDMHAYGDACGSFSL
RSELVSYLYRSRGVCCTPEQVIICSGLQPAIIAVMCLLQEKCALVAMEDPGYAGARAAYELFNADILSVPVKSDGIDIEN
LAASSAGLVHIAPSHQFPTGVVMPICRRIKLLEWAAKNDGFIIEDDYDSELRYHGRPIPSLQSIDENGRVIYMGTFSKVL
SPGMRMSYMVLPPLLAARFSSVFSDFQCTVPWLEQAVLSSFIKQGHWEKHLRKICLLKKKKHDLFVHTVDRLFGKRVRIH
GHNAGLHLLLEFPAGPDEASLVAKAATCGVRVYPASPFWRNREHSPANCLFLGYGTLTEPDIITALERLEKVWFCPEGI
>Mature_479_residues
MLYLNAAGKIPLYQQLYEQIKKEILAGIRSADAGLPSIRTMAKELQLGKNTVENAYAQLVLEGYVRVRPGSGYRVNRVYS
HMNAAELPHVNTGMVMSDEKKTTPQKHIDYDFNYENLDASIFPAAIWRRLMADILSSLHKNSRQAVDMHAYGDACGSFSL
RSELVSYLYRSRGVCCTPEQVIICSGLQPAIIAVMCLLQEKCALVAMEDPGYAGARAAYELFNADILSVPVKSDGIDIEN
LAASSAGLVHIAPSHQFPTGVVMPICRRIKLLEWAAKNDGFIIEDDYDSELRYHGRPIPSLQSIDENGRVIYMGTFSKVL
SPGMRMSYMVLPPLLAARFSSVFSDFQCTVPWLEQAVLSSFIKQGHWEKHLRKICLLKKKKHDLFVHTVDRLFGKRVRIH
GHNAGLHLLLEFPAGPDEASLVAKAATCGVRVYPASPFWRNREHSPANCLFLGYGTLTEPDIITALERLEKVWFCPEGI

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=279, Percent_Identity=23.2974910394265, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI33469970, Length=279, Percent_Identity=23.2974910394265, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787710, Length=445, Percent_Identity=26.0674157303371, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1790797, Length=462, Percent_Identity=23.8095238095238, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356535, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53521; Mature: 53521

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLNAAGKIPLYQQLYEQIKKEILAGIRSADAGLPSIRTMAKELQLGKNTVENAYAQLV
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
LEGYVRVRPGSGYRVNRVYSHMNAAELPHVNTGMVMSDEKKTTPQKHIDYDFNYENLDAS
HHCCEEEECCCCCCHHHHHHHCCHHHCCCCCCCCEECCCCCCCCHHHCCCCCCCCCCCCH
IFPAAIWRRLMADILSSLHKNSRQAVDMHAYGDACGSFSLRSELVSYLYRSRGVCCTPEQ
HHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
VIICSGLQPAIIAVMCLLQEKCALVAMEDPGYAGARAAYELFNADILSVPVKSDGIDIEN
EEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCHHH
LAASSAGLVHIAPSHQFPTGVVMPICRRIKLLEWAAKNDGFIIEDDYDSELRYHGRPIPS
HHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHCCCCCCCC
LQSIDENGRVIYMGTFSKVLSPGMRMSYMVLPPLLAARFSSVFSDFQCTVPWLEQAVLSS
HHCCCCCCCEEEEECHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FIKQGHWEKHLRKICLLKKKKHDLFVHTVDRLFGKRVRIHGHNAGLHLLLEFPAGPDEAS
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCHHH
LVAKAATCGVRVYPASPFWRNREHSPANCLFLGYGTLTEPDIITALERLEKVWFCPEGI
HHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLYLNAAGKIPLYQQLYEQIKKEILAGIRSADAGLPSIRTMAKELQLGKNTVENAYAQLV
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
LEGYVRVRPGSGYRVNRVYSHMNAAELPHVNTGMVMSDEKKTTPQKHIDYDFNYENLDAS
HHCCEEEECCCCCCHHHHHHHCCHHHCCCCCCCCEECCCCCCCCHHHCCCCCCCCCCCCH
IFPAAIWRRLMADILSSLHKNSRQAVDMHAYGDACGSFSLRSELVSYLYRSRGVCCTPEQ
HHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
VIICSGLQPAIIAVMCLLQEKCALVAMEDPGYAGARAAYELFNADILSVPVKSDGIDIEN
EEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCHHH
LAASSAGLVHIAPSHQFPTGVVMPICRRIKLLEWAAKNDGFIIEDDYDSELRYHGRPIPS
HHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHCCCCCCCC
LQSIDENGRVIYMGTFSKVLSPGMRMSYMVLPPLLAARFSSVFSDFQCTVPWLEQAVLSS
HHCCCCCCCEEEEECHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FIKQGHWEKHLRKICLLKKKKHDLFVHTVDRLFGKRVRIHGHNAGLHLLLEFPAGPDEAS
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCHHH
LVAKAATCGVRVYPASPFWRNREHSPANCLFLGYGTLTEPDIITALERLEKVWFCPEGI
HHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]