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The map label for this gene is gltB [C]

Identifier: 220904426

GI number: 220904426

Start: 1364247

End: 1365872

Strand: Direct

Name: gltB [C]

Synonym: Ddes_1156

Alternate gene names: 220904426

Gene position: 1364247-1365872 (Clockwise)

Preceding gene: 220904425

Following gene: 220904427

Centisome position: 47.48

GC content: 56.58

Gene sequence:

>1626_bases
ATGGAATCAGTAAAAACTCAGGATGTCAGCGTCAATGATCTGTGCTGGAAGATAGATTACCGGCCGGACCTGTGTACCAG
ATGCGGTTCCTGTGTGGCTGCCTGCACTTTTGCCGCCATTGAACCATCGCGGGTGCGCCGCCATATCCAGTCGCACAAGA
CTCTGGATTCTGCCCAGGAATATGCCGTCCCTCTGGTCATCAAGCAAAAAACCTCTATCAGCCATGCATGCGTGGGATGC
GGTATGTGCGAAAAAAGCTGTCCTACCGGAGCCATACGACCTGTGCGCAATATGGATCAACGCTTCGCCCTGCTGGCCCG
CGAGCATGGTCCCATAAAGCGTGGCGGGCGCAGCAACCTGACCATGCCGCGCACGCTTGACGCCATAGTCGTCGGGCGTA
TCAGTCAGATGACGGATCCTGCCCTGGATTCCGAGCGGCATACCTTTGATATGCGCTCGCCTCTGGGGCGTGTCATGCCT
GCAGGGGATCTGCCACTCAGAGTAGAGGGGACAAGCCTTGTGCTGGCAGGCCAAACGCCCAGAGTAACTTGGATTTACCC
GGTCATCTTTAGTGACATGAGTATTGGGGCATTATCCACGCGGGCTTGGGAAGCCATCGCCCTGGCCACAGCCTATCTTA
ATGAAAAATGCGGCATACCGGTACGCATGTGCTCCGGCGAAGGCGGTATGCCTGGCAAGCTGCTGGAATCAGCGCAGCTG
AAATACATGATCCTGCAAATAGCCTCGGGGCACTTCGGCTGGAACCGCATCATCAGGGCCATGCCACGAATGAAAGCCGA
TCCGGCCGGAGTACTCATAAAAATAGGGCAGGGTGCCAAACCCGGTGACGGCGGCCTGTTGCCGGCGGCCAAGGTAGCGC
CGCACATTCAGGCCATACGCGGTGTACCCAGAACTACGCTTCATTCTCCGCCCAATCATCAGGGGCTTTACTCCATTGAA
GAATCTGTGCAGAAGATGCACCTTTCTCTTAATGCGGCTTTTGGCTTTCGTGTGCCTGTGGCGATCAAGTGCGCGGCTTC
CGCCACATCCGTTTCTGTCTATAACAACCTGCTGCGCGACCCTTACAGAATTTGCGGCGGTTTTTTTATTGACGGTATCC
AGGGCGGAACGGGTGCGGCCAATGAAGTGTCTCTGGAGCACACGGGCCACCCCATAGTGTCCAAGCTGCGCGATTGCTAT
CAGGCTGCTGTGGCTCAGGGGCTTCAGGGGCAGATTCCCCTGTGGGCGGGCGGAGGCGTTGGCCTTTCGGGCAATGCAGC
GGCCGATGCCTTTAAAATGATCTGCCTTGGAGCCAACGGTATTATTATAGGTAGAATACTCATCCAGTTGCTCGGCTGCG
TAGGTAACGAGCATGGGCGCTGCAATGCCTGTAATACAGGCAAATGCCCCACCGGTATATGCACCCAGGATCCGCGTCTG
GTCAAACGTATGGATGTGGACAGAGGGGCACAGAGCATTGTGGATTACATGCTGGCTTTTGACGCCGAACTGCGCAAGCT
GATGGCGCCTGTGGGTAACAGTTCCATGCCAGTAGGGCGCTCAGATGCGCTGGTGACCACTGACAGGGCCGTTGCCGACA
AACTGGGCATCCAGTATGCCTGCTAG

Upstream 100 bases:

>100_bases
GCGGGCTTAACGCAATTTTGCCCGACCGCGATGTGGCGGAAGATATTTACCCGCATGAGCGGGAGATGGTGATAATCGGC
AATGATCTGGCGGTGCAGAG

Downstream 100 bases:

>100_bases
ATTTTAGCAAGAGGATCACAGTATGCTGCGAATGAACACGCTGCACAATCATGAACGCATGTCCACCCAGGATCTTTTGC
TGGCCATTGAAGCCGCAGTT

Product: ferredoxin-dependent glutamate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MESVKTQDVSVNDLCWKIDYRPDLCTRCGSCVAACTFAAIEPSRVRRHIQSHKTLDSAQEYAVPLVIKQKTSISHACVGC
GMCEKSCPTGAIRPVRNMDQRFALLAREHGPIKRGGRSNLTMPRTLDAIVVGRISQMTDPALDSERHTFDMRSPLGRVMP
AGDLPLRVEGTSLVLAGQTPRVTWIYPVIFSDMSIGALSTRAWEAIALATAYLNEKCGIPVRMCSGEGGMPGKLLESAQL
KYMILQIASGHFGWNRIIRAMPRMKADPAGVLIKIGQGAKPGDGGLLPAAKVAPHIQAIRGVPRTTLHSPPNHQGLYSIE
ESVQKMHLSLNAAFGFRVPVAIKCAASATSVSVYNNLLRDPYRICGGFFIDGIQGGTGAANEVSLEHTGHPIVSKLRDCY
QAAVAQGLQGQIPLWAGGGVGLSGNAAADAFKMICLGANGIIIGRILIQLLGCVGNEHGRCNACNTGKCPTGICTQDPRL
VKRMDVDRGAQSIVDYMLAFDAELRKLMAPVGNSSMPVGRSDALVTTDRAVADKLGIQYAC

Sequences:

>Translated_541_residues
MESVKTQDVSVNDLCWKIDYRPDLCTRCGSCVAACTFAAIEPSRVRRHIQSHKTLDSAQEYAVPLVIKQKTSISHACVGC
GMCEKSCPTGAIRPVRNMDQRFALLAREHGPIKRGGRSNLTMPRTLDAIVVGRISQMTDPALDSERHTFDMRSPLGRVMP
AGDLPLRVEGTSLVLAGQTPRVTWIYPVIFSDMSIGALSTRAWEAIALATAYLNEKCGIPVRMCSGEGGMPGKLLESAQL
KYMILQIASGHFGWNRIIRAMPRMKADPAGVLIKIGQGAKPGDGGLLPAAKVAPHIQAIRGVPRTTLHSPPNHQGLYSIE
ESVQKMHLSLNAAFGFRVPVAIKCAASATSVSVYNNLLRDPYRICGGFFIDGIQGGTGAANEVSLEHTGHPIVSKLRDCY
QAAVAQGLQGQIPLWAGGGVGLSGNAAADAFKMICLGANGIIIGRILIQLLGCVGNEHGRCNACNTGKCPTGICTQDPRL
VKRMDVDRGAQSIVDYMLAFDAELRKLMAPVGNSSMPVGRSDALVTTDRAVADKLGIQYAC
>Mature_541_residues
MESVKTQDVSVNDLCWKIDYRPDLCTRCGSCVAACTFAAIEPSRVRRHIQSHKTLDSAQEYAVPLVIKQKTSISHACVGC
GMCEKSCPTGAIRPVRNMDQRFALLAREHGPIKRGGRSNLTMPRTLDAIVVGRISQMTDPALDSERHTFDMRSPLGRVMP
AGDLPLRVEGTSLVLAGQTPRVTWIYPVIFSDMSIGALSTRAWEAIALATAYLNEKCGIPVRMCSGEGGMPGKLLESAQL
KYMILQIASGHFGWNRIIRAMPRMKADPAGVLIKIGQGAKPGDGGLLPAAKVAPHIQAIRGVPRTTLHSPPNHQGLYSIE
ESVQKMHLSLNAAFGFRVPVAIKCAASATSVSVYNNLLRDPYRICGGFFIDGIQGGTGAANEVSLEHTGHPIVSKLRDCY
QAAVAQGLQGQIPLWAGGGVGLSGNAAADAFKMICLGANGIIIGRILIQLLGCVGNEHGRCNACNTGKCPTGICTQDPRL
VKRMDVDRGAQSIVDYMLAFDAELRKLMAPVGNSSMPVGRSDALVTTDRAVADKLGIQYAC

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=345, Percent_Identity=32.1739130434783, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17570289, Length=354, Percent_Identity=28.2485875706215, Blast_Score=102, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320030, Length=361, Percent_Identity=28.2548476454294, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574881, Length=419, Percent_Identity=23.8663484486874, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24665539, Length=419, Percent_Identity=23.8663484486874, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013785
- InterPro:   IPR002932 [H]

Pfam domain/function: PF01645 Glu_synthase [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 57913; Mature: 57913

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVKTQDVSVNDLCWKIDYRPDLCTRCGSCVAACTFAAIEPSRVRRHIQSHKTLDSAQE
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
YAVPLVIKQKTSISHACVGCGMCEKSCPTGAIRPVRNMDQRFALLAREHGPIKRGGRSNL
HCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
TMPRTLDAIVVGRISQMTDPALDSERHTFDMRSPLGRVMPAGDLPLRVEGTSLVLAGQTP
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCHHHCCCCCCCCEEECCCEEEEECCCC
RVTWIYPVIFSDMSIGALSTRAWEAIALATAYLNEKCGIPVRMCSGEGGMPGKLLESAQL
CEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHH
KYMILQIASGHFGWNRIIRAMPRMKADPAGVLIKIGQGAKPGDGGLLPAAKVAPHIQAIR
HEEEEEHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHC
GVPRTTLHSPPNHQGLYSIEESVQKMHLSLNAAFGFRVPVAIKCAASATSVSVYNNLLRD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCEEEEECCCHHHHHHHHHHHHC
PYRICGGFFIDGIQGGTGAANEVSLEHTGHPIVSKLRDCYQAAVAQGLQGQIPLWAGGGV
HHHHHCHHEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GLSGNAAADAFKMICLGANGIIIGRILIQLLGCVGNEHGRCNACNTGKCPTGICTQDPRL
CCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
VKRMDVDRGAQSIVDYMLAFDAELRKLMAPVGNSSMPVGRSDALVTTDRAVADKLGIQYA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECHHHHHHHCCCCCC
C
C
>Mature Secondary Structure
MESVKTQDVSVNDLCWKIDYRPDLCTRCGSCVAACTFAAIEPSRVRRHIQSHKTLDSAQE
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
YAVPLVIKQKTSISHACVGCGMCEKSCPTGAIRPVRNMDQRFALLAREHGPIKRGGRSNL
HCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
TMPRTLDAIVVGRISQMTDPALDSERHTFDMRSPLGRVMPAGDLPLRVEGTSLVLAGQTP
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCHHHCCCCCCCCEEECCCEEEEECCCC
RVTWIYPVIFSDMSIGALSTRAWEAIALATAYLNEKCGIPVRMCSGEGGMPGKLLESAQL
CEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHH
KYMILQIASGHFGWNRIIRAMPRMKADPAGVLIKIGQGAKPGDGGLLPAAKVAPHIQAIR
HEEEEEHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHC
GVPRTTLHSPPNHQGLYSIEESVQKMHLSLNAAFGFRVPVAIKCAASATSVSVYNNLLRD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCEEEEECCCHHHHHHHHHHHHC
PYRICGGFFIDGIQGGTGAANEVSLEHTGHPIVSKLRDCYQAAVAQGLQGQIPLWAGGGV
HHHHHCHHEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GLSGNAAADAFKMICLGANGIIIGRILIQLLGCVGNEHGRCNACNTGKCPTGICTQDPRL
CCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
VKRMDVDRGAQSIVDYMLAFDAELRKLMAPVGNSSMPVGRSDALVTTDRAVADKLGIQYA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECHHHHHHHCCCCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]