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The map label for this gene is atoB [H]

Identifier: 21910914

GI number: 21910914

Start: 1380529

End: 1381716

Strand: Direct

Name: atoB [H]

Synonym: SpyM3_1378

Alternate gene names: 21910914

Gene position: 1380529-1381716 (Clockwise)

Preceding gene: 21910899

Following gene: 21910915

Centisome position: 72.64

GC content: 41.67

Gene sequence:

>1188_bases
ATGAAAAACATAGTTATCGTTGAAGCTTTACGAACTCCTATCGGAGCTTTTGGAGGCTCCTTTAAAAGTGTCTCTGCTGT
TGAACTTGGAACAACTGTACTGAAAAAAATCCTTGATAAAACGCAAGTAAAGCCTGAAATGGTTGATGAAGTCATCCTAG
GAAACGTCCTTCATGCAGGCCTAGGACAAAATGTGGCAAGACAAGTTGCAGTCCACTCAGGAATTCCTGAAGATAAAACA
GCTTTCACATTAGATATGGTTTGCGGTTCTGGACTTAAAGCAATCCAATTAGCTACGCAAAGCATCATGCTTGGTGACGC
TGATATCGTTATTGCTGGTGGTGTGGAAAACATGTCACAGGCAGCCTATGTGTCAACTCAGCACCGCTTTGGTCAACGTC
TTGGTAATAGTCAATTGATTGATACTCTTGTTCATGATGGTTTAACAGATGCTTTTAACAATTACCACATGGGTATTACT
GCTGAAAACGTTGCTCAGAAATATGCCATCTCAAGAGAAGAGCAAGATCAATTTGCTTTAGAAAGCCAAGAAAAAGCTGC
TAAGGCATTAGAAAATCATCGTTTTGCTGACGAAATTGTCCCTGTCTCTGTGCCTCAACGACGCAAAGATCCTTTAATTG
TTACGACGGATGAATACCCAAAAGTTGACACAAGCCTTGAAAAATTACAGCAATTACGTCCTGCTTTCCTCCCTAAAGAA
GGAACCGTTACTGCTGGAAATGCCTCAGGAATAAATGATGGTGCAGCCTTATTGATGTTAATGACTGAAGAAAAAGCTCT
TGAATTAGGGTTAACACCTTTAGTCACTATTGAAAGCTATGCTAGTGCAGGTGTTGCACCTGAACTGATGGGAACTGGAC
CAATTCCTGCCACTCAAAAAGCCCTTAAGAAAGCTGGATTAACAATTTCTGACTTGGACTTAGTGGAGTCCAATGAAGCA
TTTGCAGCACAGTCCTTGGCGGTTTTAAAAGATTTAAAGTTAAACCCAGAAATCGTGAATGTGAATGGGGGAGCCATCGC
TTTAGGTCATCCTATTGGTGCCAGTGGCGCTCGCATTCTAGTCACATTAATCCACGAAATGAAAAAACGCCAAGTGGCCA
GAGGACTAGCAACACTTTGCATTGGTGGAGGTCAAGGAACTGCTGTTATCGTGAAAAACAATACTTAG

Upstream 100 bases:

>100_bases
TTTATATGCTTATAAAAATTCTATATTTTTATTTTGAGCGTTTTCTTGTTATCTCAGAAGTACAGAAAGCGCTTTCTGAA
ACTGAAAGGATGTTTATTTT

Downstream 100 bases:

>100_bases
TCTCGTGAAAGTTGGTAGAAAAAATGTGTAAATAAATCACAATAAAAGAAGCGGTAGCTCACGTTAAAGACGATGATACC
ATTATGGTTGGTGGCTTCAT

Product: putative acetyl-CoA:acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKT
AFTLDMVCGSGLKAIQLATQSIMLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
AENVAQKYAISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEA
FAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVARGLATLCIGGGQGTAVIVKNNT

Sequences:

>Translated_395_residues
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKT
AFTLDMVCGSGLKAIQLATQSIMLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
AENVAQKYAISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEA
FAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVARGLATLCIGGGQGTAVIVKNNT
>Mature_395_residues
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKT
AFTLDMVCGSGLKAIQLATQSIMLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
AENVAQKYAISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEA
FAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVARGLATLCIGGGQGTAVIVKNNT

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=390, Percent_Identity=52.5641025641026, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI167614485, Length=394, Percent_Identity=44.1624365482233, Blast_Score=331, Evalue=6e-91,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=42.7480916030534, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI4501853, Length=396, Percent_Identity=41.6666666666667, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI4504327, Length=432, Percent_Identity=34.4907407407407, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI194353979, Length=396, Percent_Identity=31.5656565656566, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI19923233, Length=405, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082165, Length=394, Percent_Identity=57.8680203045685, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=59.0330788804071, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1787663, Length=404, Percent_Identity=43.3168316831683, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI48994986, Length=405, Percent_Identity=40.9876543209877, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1788683, Length=412, Percent_Identity=32.7669902912621, Blast_Score=213, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI133906874, Length=392, Percent_Identity=42.6020408163265, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=41.9847328244275, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI25147385, Length=395, Percent_Identity=40.5063291139241, Blast_Score=288, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI17551802, Length=426, Percent_Identity=31.6901408450704, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17535917, Length=393, Percent_Identity=32.0610687022901, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6325229, Length=398, Percent_Identity=44.2211055276382, Blast_Score=308, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6322031, Length=401, Percent_Identity=37.9052369077307, Blast_Score=241, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=48.9795918367347, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI17648125, Length=393, Percent_Identity=44.2748091603053, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI24640423, Length=390, Percent_Identity=42.5641025641026, Blast_Score=315, Evalue=3e-86,
Organism=Drosophila melanogaster, GI17137578, Length=432, Percent_Identity=33.3333333333333, Blast_Score=193, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41785; Mature: 41785

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAG
CCCEEEEHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLATQSIMLGDADIVIAGGVENMSQ
CCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHEECCCCEEEECCCCHHHH
AAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGITAENVAQKYAISREEQDQFAL
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHH
ESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQK
CEEECCCCCCCCCCEEEEEEEECHHHHHHCCCCEEEEHHHHCCCCCHHHCCCCCCCHHHH
ALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARIL
HHHHHCCEEEHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCHHHHH
VTLIHEMKKRQVARGLATLCIGGGQGTAVIVKNNT
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCC
>Mature Secondary Structure
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAG
CCCEEEEHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLATQSIMLGDADIVIAGGVENMSQ
CCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHEECCCCEEEECCCCHHHH
AAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGITAENVAQKYAISREEQDQFAL
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHH
ESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQK
CEEECCCCCCCCCCEEEEEEEECHHHHHHCCCCEEEEHHHHCCCCCHHHCCCCCCCHHHH
ALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARIL
HHHHHCCEEEHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCHHHHH
VTLIHEMKKRQVARGLATLCIGGGQGTAVIVKNNT
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA