Click here to switch to the map view.

The map label for this gene is xerS

Identifier: 21910375

GI number: 21910375

Start: 892531

End: 893601

Strand: Reverse

Name: xerS

Synonym: SpyM3_0839

Alternate gene names: 21910375

Gene position: 893601-892531 (Counterclockwise)

Preceding gene: 21910377

Following gene: 21910374

Centisome position: 47.02

GC content: 37.82

Gene sequence:

>1071_bases
ATGAGACGCGAATTATTACTAGAAAAAATTGAAACCTACAAGGCTATCATGCCTTGGTATGTTTTAGATTATTACCAATC
CAAATTAGCTGTTCCATACAGCTTTACCACCTTATATGAGTATTTAAAAGAATACAAACGCTTTTTTGATTGGCTGATGG
ATGCTGATTTAACGCAGGCGCCAAAGATTGCTGATATTGACTTGAGCACGCTTGAGCACCTTACCAAGAAGGATTTAGAG
GCCTTTGTGCTTTATTTGCGGGAACGACCTTCTCTCAACACCTATTCCACCAAAGAGGGGCTTTCTCAAACCACTATTAA
TCGGACCTTGTCTGCCCTATCAAGCCTTTACAAGTACTTGACTGAAGAGGTTGAAAATGACCAAGGGGAGCCTTATTTTT
ATCGGAATGTTATGAAAAAAGTGTCAACAAAAAAGAAAAAAGAAACCCTGGCTTCCAGAGCGGAAAATATTAAGCAGAAA
CTGTTTTTAGGTGATGAAACTCTAGCTTTCTTGGATTATGTGGATAAGGAATATGAGCAAAAATTGTCTAATCGTGCCAA
ATCTTCTTTCCGTAAAAATAAGGAGAGGGATTTGGCTATTATTGCTCTACTACTTGCTTCTGGTGTTCGTTTGTCTGAAG
CAGTGAATCTTGATTTAAAAGATGTCAATCTAAATATGATGATTATCGAAGTTATTCGCAAAGGCGGAAAACGTGATTCA
GTCAATGTAGCAGGTTTTGCGAAAGGTTATTTGGAGTCTTATTTAGCTGTTCGTCAGAGACGTTACAAGGCTGAAAAACA
GGATCTTGCTTTCTTTTTAACAGAATACCGTGGCGTTCCAAATCGAATGGATGCTTCTAGTATAGAAAAGATGGTTGGCA
AGTACTCTGAGGATTTTAAAATTCGTGTGACTCCTCATAAATTGCGTCATACGCTAGCGACAAGACTATATGATGCTACT
AAATCTCAGGTGTTAGTTAGTCATCAATTAGGCCATTCCTCTACTCAAGTCACGGATCTTTATACCCATATTGTCAATGA
TGAGCAAAAAAATGCTTTAGATAACCTTTAA

Upstream 100 bases:

>100_bases
ATATACTGCTCTTGTAGAGAATGAATGACATAAAATACATGAGACAATTTGCGAAAATTCATTTTTGAAAAAATTGTTAT
TGTTAAGGAATTATGATGAT

Downstream 100 bases:

>100_bases
TATTACATAATTATTTTTATGTAACATTAAAGGTAAAAATAGCTTCAAAATTAACTTTAATAGATGGCTACTATTAACCG
TGACAGTTTGGTGTCAGGCC

Product: site-specific tyrosine recombinase XerS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Sequences:

>Translated_356_residues
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
>Mature_356_residues
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerS subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=251, Percent_Identity=27.0916334661355, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERS_STRP1 (P67634)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269337.1
- RefSeq:   YP_282276.1
- ProteinModelPortal:   P67634
- SMR:   P67634
- EnsemblBacteria:   EBSTRT00000001626
- EnsemblBacteria:   EBSTRT00000027474
- GeneID:   3572005
- GeneID:   901303
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1196
- KEGG:   spz:M5005_Spy_0913
- GeneTree:   EBGT00050000027386
- HOGENOM:   HBG515070
- OMA:   YDDMRRE
- ProtClustDB:   PRK05084
- BioCyc:   SPYO160490:SPY1196-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0913-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01816
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 41472; Mature: 41472

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: ACT_SITE 210-210 ACT_SITE 234-234 ACT_SITE 306-306 ACT_SITE 309-309 ACT_SITE 332-332 ACT_SITE 341-341

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQ
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCCHHHHHHHHHCCCCCCC
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCE
IRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQ
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCCHHHHHHHHHCCCCCCC
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCE
IRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296