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The map label for this gene is cheM [H]

Identifier: 218931044

GI number: 218931044

Start: 4581134

End: 4583083

Strand: Direct

Name: cheM [H]

Synonym: YPO4062

Alternate gene names: 218931044

Gene position: 4581134-4583083 (Clockwise)

Preceding gene: 218931043

Following gene: 218931045

Centisome position: 98.44

GC content: 49.23

Gene sequence:

>1950_bases
ATGGCGGTATTTAGCAAAATTATTGGCAGCTTTGATAACGTAAAAGTCGGAAAAAAATTGGGTTTAAGTTTTTTCCTAAT
GTTGCTATTGGTCGGGGTCATTGCGGGCACCACCGCTTATCACTTCTCCGTGATCGAAGAACATGCATATAAAGTGGAGT
TGAGCTACAAAATCAACGACGAAGCGAATCAGGCAAAATATAACCGCGCACTTTATGAACGTACCTATGACCTGAAATAC
ATCACAGAAAACACACAGCACATCAATAATATAAAAAATTTACTGACCCAAAGTGCAAATCTCCGCTGGTCAGTTGATAA
CCGCAAAAATATTGCCAACATTAATCATGTCGTTGAGGAGTACCAGCAACAACAGACGAACTTTGTGAATGCGGTGACCA
ATAAAGATAAAGTGCGTCAAAGCTGGAGCATCTCTGAAAGCCTAAATAATATCAATGCACTACAGCAAAGCCTGCTTAAT
GAAGGGGCCGATACCAATACGCAGATATTGCTAGCAGAAATGAGCCAAAAATTAATGACGGTGCGTTACAACGCGCGCGG
TTTATTACTGGATCGCAATAAAGATGCCGAAACTGCACTGATAACCTCAATTAACATTGCCAACAGTGCCGCGAATGCTT
TCATGCCTGTGTTATCTGCCGAGCAGCAGAAACTATTAGCACCGGTTGCCGCTAACCTAGCCCTCTATAAAGACAACGTT
CTGGCCTATTTACCGGCTTATCAGCAAGAACTGGAGGTCGGTAAAGTGATGGAGGCCAGTGCGAATGCATTGAATACGTT
GGCCACCCAACTGTTTACCCAAGAGTTGCAAGGTACGCACAACGAGATTAACAATGCCCAGTACCAACTCGCTATTGCGG
CTCTTGTGGCCTTACTTTTGGGGCTATTGATCGCCTGGCGCATGACCCGTCAAATTACCGTGCCTCTACGTGCCACACTG
GATATGGCAGAACGTATTGCCACTGGCGATTTAACCGCGGCAACCACATCATCCCGTACCGACGAACTGGGCATGTTGAT
GAATGCCGTCGCCCGAATGAATGAAAATCTGCGTGCCATGATTGATGAAATCCGCATTGGTGTCAGCCAGGTATCCCATG
CCTCTGGTGAGATTGCCGCTGGCAATACTGATTTATCGTCCCGTACCGAGCAACAAGCCGCCGCCGTAGAAGAAACCGCC
GCCAGCATGGAACAATTAAACGCCACAGTAAAACAGAACACGGATAACGCTCATCACGCCAATCAATTGGCCACCGAGGC
CTCGCAGACCGCACAACAGGGCGGCAAGCTGGTCAATGATGTAGTGCGCACCATGAATGATATCTCTGGCAGTTCCAAAC
GTATTTCTGAAATCACCTCCGTGATTAACAGCATCGCTTTCCAGACCAATATTTTGGCGCTGAATGCCGCCGTTGAAGCG
GCCCGGGCGGGTGAACAAGGCCGTGGCTTTGCGGTAGTCGCCAGTGAGGTCAGAAATCTGGCACAACGTAGTGCGCAGGC
CGCTAAAGAAATTGAAGGGCTGATTGGCGAGTCTGTTTCTCAGGTTAATGCCGGAACATCGCTGGTGAAAAATGCCGGTA
ACACCATGGAGGAGATTGTCCGCTCCGTGAGCCACGTGCGCGATATCATGGCGGAAATCGCCTCAGCATCTGATGAACAA
AGCCGTGGTATCACCCAAGTTAGCTTGGCTATCTCAGAAATGGACAGTACCACGCAGCAAAATGCGGCCTTGGTGGAAGA
ATCCGCCGCCGCCGCTGACTCACTGGCTGAGCAGGCCATCTTGCTGGCTCAGGCTGTGGCGGTGTTTCGGCTATCTGAAG
ATGAAGGCGCGACAGATGAAGGCCGTGTTGTGACGCCAAAAGCCTCTAACGGGCGTCATACGCCAGAAGACCATCGGATC
AACCAGCAGAAGAGCTGGGAAACGTTCTAA

Upstream 100 bases:

>100_bases
GCGTACATACCAGTCCTTTAACTTCTCTAATAATTAGACCTTACCAAACTCACCTACGCTGATTAATTCATATCAGAAAC
ACCGTATAACGGAGAAGAAC

Downstream 100 bases:

>100_bases
TCCCTCAATATTGGCAGGAATAGCCACAACGGTTATTTCTGCCATCCTCAGAAATAATTGGCGATAAATAGGTTTCTCGT
TTTCAGGGAATTTCTTCGAC

Product: methyl-accepting chemotaxis protein II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MAVFSKIIGSFDNVKVGKKLGLSFFLMLLLVGVIAGTTAYHFSVIEEHAYKVELSYKINDEANQAKYNRALYERTYDLKY
ITENTQHINNIKNLLTQSANLRWSVDNRKNIANINHVVEEYQQQQTNFVNAVTNKDKVRQSWSISESLNNINALQQSLLN
EGADTNTQILLAEMSQKLMTVRYNARGLLLDRNKDAETALITSINIANSAANAFMPVLSAEQQKLLAPVAANLALYKDNV
LAYLPAYQQELEVGKVMEASANALNTLATQLFTQELQGTHNEINNAQYQLAIAALVALLLGLLIAWRMTRQITVPLRATL
DMAERIATGDLTAATTSSRTDELGMLMNAVARMNENLRAMIDEIRIGVSQVSHASGEIAAGNTDLSSRTEQQAAAVEETA
ASMEQLNATVKQNTDNAHHANQLATEASQTAQQGGKLVNDVVRTMNDISGSSKRISEITSVINSIAFQTNILALNAAVEA
ARAGEQGRGFAVVASEVRNLAQRSAQAAKEIEGLIGESVSQVNAGTSLVKNAGNTMEEIVRSVSHVRDIMAEIASASDEQ
SRGITQVSLAISEMDSTTQQNAALVEESAAAADSLAEQAILLAQAVAVFRLSEDEGATDEGRVVTPKASNGRHTPEDHRI
NQQKSWETF

Sequences:

>Translated_649_residues
MAVFSKIIGSFDNVKVGKKLGLSFFLMLLLVGVIAGTTAYHFSVIEEHAYKVELSYKINDEANQAKYNRALYERTYDLKY
ITENTQHINNIKNLLTQSANLRWSVDNRKNIANINHVVEEYQQQQTNFVNAVTNKDKVRQSWSISESLNNINALQQSLLN
EGADTNTQILLAEMSQKLMTVRYNARGLLLDRNKDAETALITSINIANSAANAFMPVLSAEQQKLLAPVAANLALYKDNV
LAYLPAYQQELEVGKVMEASANALNTLATQLFTQELQGTHNEINNAQYQLAIAALVALLLGLLIAWRMTRQITVPLRATL
DMAERIATGDLTAATTSSRTDELGMLMNAVARMNENLRAMIDEIRIGVSQVSHASGEIAAGNTDLSSRTEQQAAAVEETA
ASMEQLNATVKQNTDNAHHANQLATEASQTAQQGGKLVNDVVRTMNDISGSSKRISEITSVINSIAFQTNILALNAAVEA
ARAGEQGRGFAVVASEVRNLAQRSAQAAKEIEGLIGESVSQVNAGTSLVKNAGNTMEEIVRSVSHVRDIMAEIASASDEQ
SRGITQVSLAISEMDSTTQQNAALVEESAAAADSLAEQAILLAQAVAVFRLSEDEGATDEGRVVTPKASNGRHTPEDHRI
NQQKSWETF
>Mature_648_residues
AVFSKIIGSFDNVKVGKKLGLSFFLMLLLVGVIAGTTAYHFSVIEEHAYKVELSYKINDEANQAKYNRALYERTYDLKYI
TENTQHINNIKNLLTQSANLRWSVDNRKNIANINHVVEEYQQQQTNFVNAVTNKDKVRQSWSISESLNNINALQQSLLNE
GADTNTQILLAEMSQKLMTVRYNARGLLLDRNKDAETALITSINIANSAANAFMPVLSAEQQKLLAPVAANLALYKDNVL
AYLPAYQQELEVGKVMEASANALNTLATQLFTQELQGTHNEINNAQYQLAIAALVALLLGLLIAWRMTRQITVPLRATLD
MAERIATGDLTAATTSSRTDELGMLMNAVARMNENLRAMIDEIRIGVSQVSHASGEIAAGNTDLSSRTEQQAAAVEETAA
SMEQLNATVKQNTDNAHHANQLATEASQTAQQGGKLVNDVVRTMNDISGSSKRISEITSVINSIAFQTNILALNAAVEAA
RAGEQGRGFAVVASEVRNLAQRSAQAAKEIEGLIGESVSQVNAGTSLVKNAGNTMEEIVRSVSHVRDIMAEIASASDEQS
RGITQVSLAISEMDSTTQQNAALVEESAAAADSLAEQAILLAQAVAVFRLSEDEGATDEGRVVTPKASNGRHTPEDHRIN
QQKSWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=321, Percent_Identity=61.6822429906542, Blast_Score=351, Evalue=1e-97,
Organism=Escherichia coli, GI1788195, Length=347, Percent_Identity=57.0605187319885, Blast_Score=331, Evalue=8e-92,
Organism=Escherichia coli, GI2367378, Length=373, Percent_Identity=54.4235924932976, Blast_Score=329, Evalue=3e-91,
Organism=Escherichia coli, GI1788194, Length=338, Percent_Identity=52.6627218934911, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=43.7106918238994, Blast_Score=239, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 70520; Mature: 70389

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFSKIIGSFDNVKVGKKLGLSFFLMLLLVGVIAGTTAYHFSVIEEHAYKVELSYKIND
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEEECC
EANQAKYNRALYERTYDLKYITENTQHINNIKNLLTQSANLRWSVDNRKNIANINHVVEE
CHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHH
YQQQQTNFVNAVTNKDKVRQSWSISESLNNINALQQSLLNEGADTNTQILLAEMSQKLMT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHE
VRYNARGLLLDRNKDAETALITSINIANSAANAFMPVLSAEQQKLLAPVAANLALYKDNV
EEECCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LAYLPAYQQELEVGKVMEASANALNTLATQLFTQELQGTHNEINNAQYQLAIAALVALLL
HEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHH
GLLIAWRMTRQITVPLRATLDMAERIATGDLTAATTSSRTDELGMLMNAVARMNENLRAM
HHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHH
IDEIRIGVSQVSHASGEIAAGNTDLSSRTEQQAAAVEETAASMEQLNATVKQNTDNAHHA
HHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NQLATEASQTAQQGGKLVNDVVRTMNDISGSSKRISEITSVINSIAFQTNILALNAAVEA
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAGEQGRGFAVVASEVRNLAQRSAQAAKEIEGLIGESVSQVNAGTSLVKNAGNTMEEIV
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RSVSHVRDIMAEIASASDEQSRGITQVSLAISEMDSTTQQNAALVEESAAAADSLAEQAI
HHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAQAVAVFRLSEDEGATDEGRVVTPKASNGRHTPEDHRINQQKSWETF
HHHHHHHHHEECCCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVFSKIIGSFDNVKVGKKLGLSFFLMLLLVGVIAGTTAYHFSVIEEHAYKVELSYKIND
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEEECC
EANQAKYNRALYERTYDLKYITENTQHINNIKNLLTQSANLRWSVDNRKNIANINHVVEE
CHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHH
YQQQQTNFVNAVTNKDKVRQSWSISESLNNINALQQSLLNEGADTNTQILLAEMSQKLMT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHE
VRYNARGLLLDRNKDAETALITSINIANSAANAFMPVLSAEQQKLLAPVAANLALYKDNV
EEECCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LAYLPAYQQELEVGKVMEASANALNTLATQLFTQELQGTHNEINNAQYQLAIAALVALLL
HEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHH
GLLIAWRMTRQITVPLRATLDMAERIATGDLTAATTSSRTDELGMLMNAVARMNENLRAM
HHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHH
IDEIRIGVSQVSHASGEIAAGNTDLSSRTEQQAAAVEETAASMEQLNATVKQNTDNAHHA
HHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NQLATEASQTAQQGGKLVNDVVRTMNDISGSSKRISEITSVINSIAFQTNILALNAAVEA
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAGEQGRGFAVVASEVRNLAQRSAQAAKEIEGLIGESVSQVNAGTSLVKNAGNTMEEIV
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RSVSHVRDIMAEIASASDEQSRGITQVSLAISEMDSTTQQNAALVEESAAAADSLAEQAI
HHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAQAVAVFRLSEDEGATDEGRVVTPKASNGRHTPEDHRINQQKSWETF
HHHHHHHHHEECCCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2496104 [H]