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The map label for this gene is argE

Identifier: 218930926

GI number: 218930926

Start: 4412650

End: 4413819

Strand: Direct

Name: argE

Synonym: YPO3928

Alternate gene names: 218930926

Gene position: 4412650-4413819 (Clockwise)

Preceding gene: 218930917

Following gene: 218930927

Centisome position: 94.82

GC content: 50.43

Gene sequence:

>1170_bases
GTGAAGATGAAATTACCTCCATTTATTGAGCTGTACCGGGCGTTAATTGCAACGCCTTCGATCAGCGCCGCTGATAGTGC
CCTCGACCAAAGTAATGAGGCATTAATCAATTTGTTAGCCGGATGGTTTGCAGACCTGGGTTTTCGCGTCGAGATCCAGC
CGGTGCCTGATACTCGCCACAAATTTAACCTGTTAGCCAGCATTGGCGAAAATGAAAACGGGGAAGGTCATGGCGGGTTA
TTGCTGGCGGGTCATACCGATACTGTCCCTTACGATGAAGGGCGCTGGACCCGCGATCCCTTCACCTTGACCGAGCATGA
CCATAAACTCTATGGCTTGGGTACCGCAGATATGAAAGGCTTTTTTGCTTTTATTCTGGATGCGGTGCGCGATATTGATG
CCAGCAAGTTGACCAAACCGCTCTATATTTTGGCAACTGCCGATGAAGAGACCACCATGGCAGGTGCGCGTTATTTTGCT
GCGAATACCCAGCTACGCCCTGATTTCGCGATTATCGGCGAGCCAACCTCACTGCAACCTGTCCGTGCGCACAAAGGCCA
TATCTCCAACGCCATTCGTATTACCGGCCAGTCTGGGCACTCCAGTGATCCGGCCCGGGGGGTGAATGCCATTGATTTGA
TGCATGAATCTATTACGCAATTGATGGCGCTGCGTACCACACTGCAAGAGCGTTATCACAATCCAGCGTTTACTATTCCT
TATCCCACCATGAATTTTGGTCATATTAATGGCGGTGATGCGGCAAACCGTATCTGTGCGTGTTGTGAATTACATATGGA
TATCCGTCCGTTACCGGGCCTGACATTAAGTGATTTAAATGAGTTAATGACCGAAGCGCTGGAACCGGTGAGTCAACGCT
GGCCGGGGCGTCTCAGTATTGATGAGTTGCACCCTCCGATCCCTGGCTATGAGTGCCCAACAGACCATCATATGGTCGGC
GTGATCGAGAAACTGCTCGGTGAGCGCACTGCGGTGGTGAACTATTGCACCGAAGCCCCTTTTATTCAGCAAGTCTGCCC
GACATTAGTGCTGGGGCCAGGTTCGATTAATCAGGCACATCAGCCAGATGAATTTATTGATATGGCCTTTATCGAACCAA
CACGTGAGCTGATTGGTCAGCTAGTTGACCACTTTTGCCAGCAGAAATAA

Upstream 100 bases:

>100_bases
TTAAGGGTCAGTTTAGGTTCCCTTTCGCTCAAGCTTACTGTATTTTTATTCATAATTACTGCATGAATATTGATACTATC
CTAACCAAAGGCTGTCAACA

Downstream 100 bases:

>100_bases
CTATAATGGGGTAGACGATCAATATTGCCGATAAGCCAGACTGATAATCTCACCTCAGTAATTAAATTTCAGAAATATCC
CTAAAATTGATGTTTTTTTA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGL
LLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFA
ANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIP
YPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVG
VIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK

Sequences:

>Translated_389_residues
MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGL
LLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFA
ANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIP
YPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVG
VIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
>Mature_389_residues
MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGL
LLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFA
ANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIP
YPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVG
VIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily

Homologues:

Organism=Escherichia coli, GI1790395, Length=386, Percent_Identity=77.720207253886, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1788816, Length=264, Percent_Identity=28.7878787878788, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789236, Length=378, Percent_Identity=24.6031746031746, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551016, Length=361, Percent_Identity=24.9307479224377, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGE_YERP3 (A7FCZ8)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399126.1
- ProteinModelPortal:   A7FCZ8
- SMR:   A7FCZ8
- STRING:   A7FCZ8
- GeneID:   5387501
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_0126
- eggNOG:   COG0624
- HOGENOM:   HBG728841
- OMA:   RICGQCA
- ProtClustDB:   PRK05111
- BioCyc:   YPSE349747:YPSIP31758_0126-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_01108
- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- TIGRFAMs:   TIGR01892

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.5.1.16

Molecular weight: Translated: 42950; Mature: 42950

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 87-87 ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRH
CCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHH
KFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKG
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEECCCCCEEEECCCHHHHH
FFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQP
HHHHHHHHHHCCCHHHCCCCEEEEEECCCCHHHHHHHEEECCCCCCCCEEEECCCCCCCC
VRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIP
HHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
YPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSI
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
DELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAH
HHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCHHEEECCCCCCCCC
QPDEFIDMAFIEPTRELIGQLVDHFCQQK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRH
CCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHH
KFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKG
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEECCCCCEEEECCCHHHHH
FFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQP
HHHHHHHHHHCCCHHHCCCCEEEEEECCCCHHHHHHHEEECCCCCCCCEEEECCCCCCCC
VRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIP
HHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
YPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSI
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
DELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAH
HHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCHHEEECCCCCCCCC
QPDEFIDMAFIEPTRELIGQLVDHFCQQK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA