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The map label for this gene is pldA [H]

Identifier: 218930837

GI number: 218930837

Start: 4302504

End: 4303382

Strand: Reverse

Name: pldA [H]

Synonym: YPO3834

Alternate gene names: 218930837

Gene position: 4303382-4302504 (Counterclockwise)

Preceding gene: 218930840

Following gene: 218930836

Centisome position: 92.47

GC content: 45.96

Gene sequence:

>879_bases
ATGGCGAGATTTTGGCAGATACTGATTGCGTTATTACTGGTGCCAACATTGGCACAGGCTGAAGAAGCAACGATTGAAAA
GATTCATGATGCGCCCGCAGTGCGTGGCAGTATTATCGCGGCAATGTTGCAGGACCACGATAATCCTTTCCTACTTTATC
CGTATGAAACCAACTATTTGCTCTACACCTATACCAACGAGATCAATAAACAAGCCATTAGCTCGTATGATTGGGCTGAA
CAGGCGAATAAAGATGAAGTAAAATTCCAACTGAGTTTAGCTTTCCCTATCTGGCGTGGTATTGCCGGGGATAACTCATT
ATTGGGGGCTTCTTATACCCAGCGTTCATGGTGGCAGGCATCCAACAGTGAAGAATCTTCACCTTTTCGTGAAACCAACT
ACGAGCCACAGCTGTTTTTGGCGTGGTCAACAGATTACGAATTGGCTGGCTGGACTTTCCGCGAAGTCGAATTTGGTTTT
AACCATCAATCCAACGGTAAAGCTGACCCAACCTCACGTAGTTGGAACCGTGTTTATACCCGCGTGATGGCACAACGTGG
CAATTTGGAAATCGACCTGAAGCCTTGGTATCGTATTCCTGAAAGCGACAGTAAAGATGATAACCCTGATATTACGAAAT
ACATGGGGTATTATCGCCTGAAAGTCGGCTATGCCCTGGGTGACAGCGTATTCAGCCTTGATGGTCGCTATAACTGGAAT
ACCGGTTACGGTGGCGCGGAAATGGGCTGGAGCTACCCAATTACCAAACATGTTCGCTTCTATACTCAGGTATTCAGTGG
CTACGGTGAGTCAATGATTGACTATAACTTTAGGCAAACACGGGTGGGTGTAGGTATCATGTTGAACGATGTCCTTTAA

Upstream 100 bases:

>100_bases
AAATCATAAAGATAAACAACACTAATCCAAGGTAACATTTGTGTGTAGAATGAGCTGTTTTCATTAAAAATAGAAATAAT
CCGAGGGTGGTGAGGGAATT

Downstream 100 bases:

>100_bases
CGTCATCCGGCGTTATCACAGTTTCAGACACAGGCCGGTTAGCCGGCCTGTGCAGATCTAATAGTTGGGGGAAAAGTGTG
TCGACCGCAGCAGTGATAAA

Product: phospholipase A

Products: NA

Alternate protein names: Detergent-resistant phospholipase A; DR-phospholipase A; Outer membrane phospholipase A; OM PLA; OMPLA; Phosphatidylcholine 1-acylhydrolase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MARFWQILIALLLVPTLAQAEEATIEKIHDAPAVRGSIIAAMLQDHDNPFLLYPYETNYLLYTYTNEINKQAISSYDWAE
QANKDEVKFQLSLAFPIWRGIAGDNSLLGASYTQRSWWQASNSEESSPFRETNYEPQLFLAWSTDYELAGWTFREVEFGF
NHQSNGKADPTSRSWNRVYTRVMAQRGNLEIDLKPWYRIPESDSKDDNPDITKYMGYYRLKVGYALGDSVFSLDGRYNWN
TGYGGAEMGWSYPITKHVRFYTQVFSGYGESMIDYNFRQTRVGVGIMLNDVL

Sequences:

>Translated_292_residues
MARFWQILIALLLVPTLAQAEEATIEKIHDAPAVRGSIIAAMLQDHDNPFLLYPYETNYLLYTYTNEINKQAISSYDWAE
QANKDEVKFQLSLAFPIWRGIAGDNSLLGASYTQRSWWQASNSEESSPFRETNYEPQLFLAWSTDYELAGWTFREVEFGF
NHQSNGKADPTSRSWNRVYTRVMAQRGNLEIDLKPWYRIPESDSKDDNPDITKYMGYYRLKVGYALGDSVFSLDGRYNWN
TGYGGAEMGWSYPITKHVRFYTQVFSGYGESMIDYNFRQTRVGVGIMLNDVL
>Mature_291_residues
ARFWQILIALLLVPTLAQAEEATIEKIHDAPAVRGSIIAAMLQDHDNPFLLYPYETNYLLYTYTNEINKQAISSYDWAEQ
ANKDEVKFQLSLAFPIWRGIAGDNSLLGASYTQRSWWQASNSEESSPFRETNYEPQLFLAWSTDYELAGWTFREVEFGFN
HQSNGKADPTSRSWNRVYTRVMAQRGNLEIDLKPWYRIPESDSKDDNPDITKYMGYYRLKVGYALGDSVFSLDGRYNWNT
GYGGAEMGWSYPITKHVRFYTQVFSGYGESMIDYNFRQTRVGVGIMLNDVL

Specific function: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities [H]

COG id: COG2829

COG function: function code M; Outer membrane phospholipase A

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein. Note=One of the very few enzymes located there (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phospholipase A1 family [H]

Homologues:

Organism=Escherichia coli, GI2367300, Length=285, Percent_Identity=71.9298245614035, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003187 [H]

Pfam domain/function: PF02253 PLA1 [H]

EC number: =3.1.1.32; =3.1.1.4 [H]

Molecular weight: Translated: 33759; Mature: 33628

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFWQILIALLLVPTLAQAEEATIEKIHDAPAVRGSIIAAMLQDHDNPFLLYPYETNYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCEE
LYTYTNEINKQAISSYDWAEQANKDEVKFQLSLAFPIWRGIAGDNSLLGASYTQRSWWQA
EEEECCHHHHHHHHCCCHHHHCCCCCEEEEEEEECHHHHCCCCCCCEECCCCCHHHHHCC
SNSEESSPFRETNYEPQLFLAWSTDYELAGWTFREVEFGFNHQSNGKADPTSRSWNRVYT
CCCCCCCCCHHCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHH
RVMAQRGNLEIDLKPWYRIPESDSKDDNPDITKYMGYYRLKVGYALGDSVFSLDGRYNWN
HHHHHCCCEEEEECCCEECCCCCCCCCCCCHHHHCCEEEEEEEEEECCCEEEECCEEECC
TGYGGAEMGWSYPITKHVRFYTQVFSGYGESMIDYNFRQTRVGVGIMLNDVL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHEEEEEEEEECCC
>Mature Secondary Structure 
ARFWQILIALLLVPTLAQAEEATIEKIHDAPAVRGSIIAAMLQDHDNPFLLYPYETNYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCEE
LYTYTNEINKQAISSYDWAEQANKDEVKFQLSLAFPIWRGIAGDNSLLGASYTQRSWWQA
EEEECCHHHHHHHHCCCHHHHCCCCCEEEEEEEECHHHHCCCCCCCEECCCCCHHHHHCC
SNSEESSPFRETNYEPQLFLAWSTDYELAGWTFREVEFGFNHQSNGKADPTSRSWNRVYT
CCCCCCCCCHHCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHH
RVMAQRGNLEIDLKPWYRIPESDSKDDNPDITKYMGYYRLKVGYALGDSVFSLDGRYNWN
HHHHHCCCEEEEECCCEECCCCCCCCCCCCHHHHCCEEEEEEEEEECCCEEEECCEEECC
TGYGGAEMGWSYPITKHVRFYTQVFSGYGESMIDYNFRQTRVGVGIMLNDVL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]