Click here to switch to the map view.

The map label for this gene is recQ [H]

Identifier: 218930836

GI number: 218930836

Start: 4300594

End: 4302426

Strand: Reverse

Name: recQ [H]

Synonym: YPO3833

Alternate gene names: 218930836

Gene position: 4302426-4300594 (Counterclockwise)

Preceding gene: 218930837

Following gene: 218930835

Centisome position: 92.45

GC content: 52.59

Gene sequence:

>1833_bases
GTGTCGACCGCAGCAGTGATAAACAGGGAATTACTGGCAGTGCAGGTATTGCGAGATACTTTTGGTTATCAGCAATTTCG
GCCAGGGCAGCAGGAGATCATCAACGCGACATTGTCAGGCCAGGATTGTCTGGTTGTGATGCCAACTGGCGGCGGTAAGT
CCTTGTGTTATCAGATCCCTGCCTTGGTGACCGATGGGCTGACATTGGTGGTTTCACCGCTTATCTCTCTGATGAAAGAT
CAGGTTGACCAACTGTTGGCCTATGGCGTGGGCGCGGGTTGTCTAAACTCATCGCAGACCCGTGAACAGCAACTGGCCGT
TATGGATGGTTGCCGCAGTGGGCAGATTAAATTGCTGTATATCGCGCCAGAACGGTTGGTGATGGAGAGTTTTCTTGATC
AACTGTATCAATGGCGACCCGCCTTGCTGGCAGTGGATGAGGCTCACTGTATTTCCCAATGGGGGCATGATTTCCGCCCG
GAATACCGTGCTCTTGGTCAGTTAAAGCAGCGTTTCCCTGATCTACCGGTTATTGCATTGACCGCTACGGCTGATGAAGC
GACGCGTGGCGATATTGTGCGCCTGTTGAATCTGGATCAACCTCTGATTCAGATCAGTAGTTTTGATCGCCCGAATATCC
GCTATACCTTAGTTGAGAAGTTTAAACCTCTCGATCAACTGTGGCGTTTTGTACAAGACCAGCGCGGCAAGAGCGGCATT
ATTTACTGTAATAGCCGAGCGAAAGTGGAAGATACGACCGCCCGTTTGCAAAGCCGTGGCTTGAGTGTTGCCGCCTATCA
CGCCGGGCTGGATAACGAGCGCCGTGCTCAGGTGCAAGAGGCTTTCCAGCGCGATGACTTACAAGTGGTGGTCGCCACCG
TAGCGTTTGGAATGGGGATTAACAAACCGAACGTCCGCTTTGTCGTGCATTTTGATATCCCACGCACCATCGAATCCTAC
TATCAGGAAACGGGGCGCGCCGGGCGTGATGGCTTACCGGCTGAGGCCGTGTTGTTGTACGATCCGGCAGATATGGCGTG
GTTACGCCGTTGTCTTGAAGAGAAACCTGCGGGTGCTCAGCAAGATATCGAACGGCATAAACTCAATGCGATGGGGGCAT
TTGCCGAAGCGCAAACCTGTCGCCGTTTGGTGCTGCTCAACTATTTTGGTGAAGGTAAACAGCAGCCATGCGGTAACTGC
GATATTTGTCTGGATCCGCCAAAGCGCTACGATGGTCTGGCAGATGCGCAAAAGGCGCTCTCTTGCGTCTATCGGGTAGG
GCAACGCTTTGGCTTAGGGTACATCGTTGAGGTGCTGCGTGGGGCGAATAACCAGCGTATTCGTGAGATGGGCCATGACA
AGCTTTCGGTGTACGGCATTGGCCGTGAGCAAACCCATGAACACTGGGTCAGCGTCTTGCGCCAGTTGATCCATTTGGGG
CTGCTCAGCCAGAATATTGCCCAGTTCTCTGCCTTGCAACTGACTGAAGCGGCGCGCCCGGTCTTACGCGCAGAGCTGCC
ATTACAACTGGCGGTACCGCGTATTCAGAGCCTGAAAGTGCGTAGCAGTGCCAATCAGAAATCCTATGGTGGCAATTATG
ATCGCAAGTTGTTCGCTAAGCTGCGCAAACTGCGTAAATCAATTGCTGATGAAGGCAATATCCCGCCTTATGTGGTGTTT
AACGATGCGACCTTGCTGGAGATGGCTGAGCAGATGCCGATTACTGCCAGCGAGCTATTGAGCGTGAATGGTGTCGGTCA
GCGTAAACTAGAACGTTTTGGTGCACCATTTATGGCCCTGATCCGTGATCATGTGGATAACAACGATGACTAA

Upstream 100 bases:

>100_bases
TCATGTTGAACGATGTCCTTTAACGTCATCCGGCGTTATCACAGTTTCAGACACAGGCCGGTTAGCCGGCCTGTGCAGAT
CTAATAGTTGGGGGAAAAGT

Downstream 100 bases:

>100_bases
ATAGATCGGGTTAGCCGTTGGTGCTACCCGATGATCCTATCAACGATAAAAATCGAATTGCGTGTTAGCATAATTTTTCG
ATCTTCCCTGTTATGAGTGG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSTAAVINRELLAVQVLRDTFGYQQFRPGQQEIINATLSGQDCLVVMPTGGGKSLCYQIPALVTDGLTLVVSPLISLMKD
QVDQLLAYGVGAGCLNSSQTREQQLAVMDGCRSGQIKLLYIAPERLVMESFLDQLYQWRPALLAVDEAHCISQWGHDFRP
EYRALGQLKQRFPDLPVIALTATADEATRGDIVRLLNLDQPLIQISSFDRPNIRYTLVEKFKPLDQLWRFVQDQRGKSGI
IYCNSRAKVEDTTARLQSRGLSVAAYHAGLDNERRAQVQEAFQRDDLQVVVATVAFGMGINKPNVRFVVHFDIPRTIESY
YQETGRAGRDGLPAEAVLLYDPADMAWLRRCLEEKPAGAQQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGKQQPCGNC
DICLDPPKRYDGLADAQKALSCVYRVGQRFGLGYIVEVLRGANNQRIREMGHDKLSVYGIGREQTHEHWVSVLRQLIHLG
LLSQNIAQFSALQLTEAARPVLRAELPLQLAVPRIQSLKVRSSANQKSYGGNYDRKLFAKLRKLRKSIADEGNIPPYVVF
NDATLLEMAEQMPITASELLSVNGVGQRKLERFGAPFMALIRDHVDNNDD

Sequences:

>Translated_610_residues
MSTAAVINRELLAVQVLRDTFGYQQFRPGQQEIINATLSGQDCLVVMPTGGGKSLCYQIPALVTDGLTLVVSPLISLMKD
QVDQLLAYGVGAGCLNSSQTREQQLAVMDGCRSGQIKLLYIAPERLVMESFLDQLYQWRPALLAVDEAHCISQWGHDFRP
EYRALGQLKQRFPDLPVIALTATADEATRGDIVRLLNLDQPLIQISSFDRPNIRYTLVEKFKPLDQLWRFVQDQRGKSGI
IYCNSRAKVEDTTARLQSRGLSVAAYHAGLDNERRAQVQEAFQRDDLQVVVATVAFGMGINKPNVRFVVHFDIPRTIESY
YQETGRAGRDGLPAEAVLLYDPADMAWLRRCLEEKPAGAQQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGKQQPCGNC
DICLDPPKRYDGLADAQKALSCVYRVGQRFGLGYIVEVLRGANNQRIREMGHDKLSVYGIGREQTHEHWVSVLRQLIHLG
LLSQNIAQFSALQLTEAARPVLRAELPLQLAVPRIQSLKVRSSANQKSYGGNYDRKLFAKLRKLRKSIADEGNIPPYVVF
NDATLLEMAEQMPITASELLSVNGVGQRKLERFGAPFMALIRDHVDNNDD
>Mature_609_residues
STAAVINRELLAVQVLRDTFGYQQFRPGQQEIINATLSGQDCLVVMPTGGGKSLCYQIPALVTDGLTLVVSPLISLMKDQ
VDQLLAYGVGAGCLNSSQTREQQLAVMDGCRSGQIKLLYIAPERLVMESFLDQLYQWRPALLAVDEAHCISQWGHDFRPE
YRALGQLKQRFPDLPVIALTATADEATRGDIVRLLNLDQPLIQISSFDRPNIRYTLVEKFKPLDQLWRFVQDQRGKSGII
YCNSRAKVEDTTARLQSRGLSVAAYHAGLDNERRAQVQEAFQRDDLQVVVATVAFGMGINKPNVRFVVHFDIPRTIESYY
QETGRAGRDGLPAEAVLLYDPADMAWLRRCLEEKPAGAQQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGKQQPCGNCD
ICLDPPKRYDGLADAQKALSCVYRVGQRFGLGYIVEVLRGANNQRIREMGHDKLSVYGIGREQTHEHWVSVLRQLIHLGL
LSQNIAQFSALQLTEAARPVLRAELPLQLAVPRIQSLKVRSSANQKSYGGNYDRKLFAKLRKLRKSIADEGNIPPYVVFN
DATLLEMAEQMPITASELLSVNGVGQRKLERFGAPFMALIRDHVDNNDD

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=648, Percent_Identity=33.4876543209877, Blast_Score=345, Evalue=1e-94,
Organism=Homo sapiens, GI110735439, Length=701, Percent_Identity=32.0970042796006, Blast_Score=332, Evalue=8e-91,
Organism=Homo sapiens, GI169218196, Length=701, Percent_Identity=32.0970042796006, Blast_Score=332, Evalue=9e-91,
Organism=Homo sapiens, GI14591902, Length=406, Percent_Identity=40.8866995073892, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI14591904, Length=406, Percent_Identity=40.8866995073892, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI148612816, Length=462, Percent_Identity=37.6623376623377, Blast_Score=269, Evalue=7e-72,
Organism=Homo sapiens, GI51242947, Length=353, Percent_Identity=41.9263456090652, Blast_Score=259, Evalue=7e-69,
Organism=Homo sapiens, GI51242943, Length=353, Percent_Identity=41.9263456090652, Blast_Score=258, Evalue=9e-69,
Organism=Homo sapiens, GI284005309, Length=358, Percent_Identity=40.2234636871508, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI13514831, Length=353, Percent_Identity=24.3626062322946, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI45446747, Length=377, Percent_Identity=23.342175066313, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI45446743, Length=377, Percent_Identity=23.342175066313, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI262118318, Length=386, Percent_Identity=22.7979274611399, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI148613856, Length=349, Percent_Identity=24.6418338108883, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI38201710, Length=349, Percent_Identity=24.6418338108883, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI222352149, Length=338, Percent_Identity=26.3313609467456, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI13518015, Length=386, Percent_Identity=22.7979274611399, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262231852, Length=386, Percent_Identity=22.7979274611399, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI216548263, Length=386, Percent_Identity=22.7979274611399, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4758138, Length=337, Percent_Identity=24.0356083086053, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI48994977, Length=610, Percent_Identity=81.1475409836066, Blast_Score=1039, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=25.4335260115607, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790214, Length=342, Percent_Identity=22.5146198830409, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=658, Percent_Identity=35.1063829787234, Blast_Score=354, Evalue=9e-98,
Organism=Caenorhabditis elegans, GI71987997, Length=406, Percent_Identity=39.6551724137931, Blast_Score=309, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI71987993, Length=406, Percent_Identity=39.6551724137931, Blast_Score=308, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI32564293, Length=682, Percent_Identity=31.3782991202346, Blast_Score=303, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17552866, Length=438, Percent_Identity=35.6164383561644, Blast_Score=245, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17537549, Length=384, Percent_Identity=24.21875, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533224, Length=329, Percent_Identity=22.1884498480243, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71987143, Length=359, Percent_Identity=22.8412256267409, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507121, Length=111, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995724, Length=111, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555296, Length=337, Percent_Identity=22.2551928783383, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=539, Percent_Identity=38.2189239332096, Blast_Score=358, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6320224, Length=358, Percent_Identity=25.6983240223464, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324217, Length=327, Percent_Identity=25.6880733944954, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319714, Length=454, Percent_Identity=23.1277533039648, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646066, Length=628, Percent_Identity=34.7133757961783, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24664226, Length=449, Percent_Identity=38.3073496659243, Blast_Score=293, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24664230, Length=449, Percent_Identity=38.3073496659243, Blast_Score=289, Evalue=4e-78,
Organism=Drosophila melanogaster, GI62472181, Length=449, Percent_Identity=38.3073496659243, Blast_Score=289, Evalue=4e-78,
Organism=Drosophila melanogaster, GI21358123, Length=365, Percent_Identity=39.4520547945205, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24642822, Length=367, Percent_Identity=22.8882833787466, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574962, Length=338, Percent_Identity=24.8520710059172, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI18857967, Length=348, Percent_Identity=23.5632183908046, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355075, Length=370, Percent_Identity=20.8108108108108, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662330, Length=363, Percent_Identity=23.4159779614325, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68314; Mature: 68183

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAAVINRELLAVQVLRDTFGYQQFRPGQQEIINATLSGQDCLVVMPTGGGKSLCYQIP
CCCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHEECCCCEEEEEECCCCCHHHHHHH
ALVTDGLTLVVSPLISLMKDQVDQLLAYGVGAGCLNSSQTREQQLAVMDGCRSGQIKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
IAPERLVMESFLDQLYQWRPALLAVDEAHCISQWGHDFRPEYRALGQLKQRFPDLPVIAL
ECHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
TATADEATRGDIVRLLNLDQPLIQISSFDRPNIRYTLVEKFKPLDQLWRFVQDQRGKSGI
EECCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCEEHHHHHCCCHHHHHHHHHHCCCCCCE
IYCNSRAKVEDTTARLQSRGLSVAAYHAGLDNERRAQVQEAFQRDDLQVVVATVAFGMGI
EEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
NKPNVRFVVHFDIPRTIESYYQETGRAGRDGLPAEAVLLYDPADMAWLRRCLEEKPAGAQ
CCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCH
QDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGKQQPCGNCDICLDPPKRYDGLADAQKAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHCCHHHHHHHH
SCVYRVGQRFGLGYIVEVLRGANNQRIREMGHDKLSVYGIGREQTHEHWVSVLRQLIHLG
HHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
LLSQNIAQFSALQLTEAARPVLRAELPLQLAVPRIQSLKVRSSANQKSYGGNYDRKLFAK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
LRKLRKSIADEGNIPPYVVFNDATLLEMAEQMPITASELLSVNGVGQRKLERFGAPFMAL
HHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCHHHHH
IRDHVDNNDD
HHHHCCCCCC
>Mature Secondary Structure 
STAAVINRELLAVQVLRDTFGYQQFRPGQQEIINATLSGQDCLVVMPTGGGKSLCYQIP
CCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHEECCCCEEEEEECCCCCHHHHHHH
ALVTDGLTLVVSPLISLMKDQVDQLLAYGVGAGCLNSSQTREQQLAVMDGCRSGQIKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
IAPERLVMESFLDQLYQWRPALLAVDEAHCISQWGHDFRPEYRALGQLKQRFPDLPVIAL
ECHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
TATADEATRGDIVRLLNLDQPLIQISSFDRPNIRYTLVEKFKPLDQLWRFVQDQRGKSGI
EECCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCEEHHHHHCCCHHHHHHHHHHCCCCCCE
IYCNSRAKVEDTTARLQSRGLSVAAYHAGLDNERRAQVQEAFQRDDLQVVVATVAFGMGI
EEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
NKPNVRFVVHFDIPRTIESYYQETGRAGRDGLPAEAVLLYDPADMAWLRRCLEEKPAGAQ
CCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCH
QDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGKQQPCGNCDICLDPPKRYDGLADAQKAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHCCHHHHHHHH
SCVYRVGQRFGLGYIVEVLRGANNQRIREMGHDKLSVYGIGREQTHEHWVSVLRQLIHLG
HHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
LLSQNIAQFSALQLTEAARPVLRAELPLQLAVPRIQSLKVRSSANQKSYGGNYDRKLFAK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
LRKLRKSIADEGNIPPYVVFNDATLLEMAEQMPITASELLSVNGVGQRKLERFGAPFMAL
HHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCHHHHH
IRDHVDNNDD
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]