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The map label for this gene is yrbG [H]

Identifier: 218930588

GI number: 218930588

Start: 3987697

End: 3988671

Strand: Direct

Name: yrbG [H]

Synonym: YPO3576

Alternate gene names: 218930588

Gene position: 3987697-3988671 (Clockwise)

Preceding gene: 218930580

Following gene: 218930589

Centisome position: 85.69

GC content: 49.85

Gene sequence:

>975_bases
ATGTTTCTTGCGATAACACTATTAATCATTGGCTTGGTTTTATTAGTGTATGGCGCTGATCGATTAGTTTACGGTGCCGC
AGTGTTATCCCGTTCTTTTGGGGTCCCCCCTCTCATTATCGGGATGACCATCGTCGGTATTGGTACATCGCTACCGGAAC
TCATTGTTTCAGTTACAGCGGCATTGAATGGCCAAACGGATATGGCGGTGGGTAATGTGCTCGGCTCCAATATTACCAAC
CTATTGCTGATTGTAGGAGGGGCGGCACTTATTCGCCCGCTGATTGTACGCTCAGAGATTCTGCGGCGGGAGTTGCCACT
GATGCTCGTGGTCACGGCGTTATGTGGTTTTCTGCTGGCAGATAACCACCTCAGCCGCGGAGATGGTGTCATCTTGCTCT
TGGCTGCTGCCGCTTTTATTGTTCTGATGCTCAAAATCGCACGCCTGGCTCATGCGGAAGGGAATGATATCTTAACCCGT
GAACAACTATCTGAATTACCACAAGATAGTAGCACTACCGTGGCGTTGTTGTGGCTCGTATTAGCCTTCATTATTTTACC
GCTCTCCGCCAAGATGATTATCGATAATGCGACGGTCATTGCCCGGGTGGCCGGTGTCAGCGAGTTGGTCATTGGGCTGA
CAGTGATCGCTATCGGCACCAGTTTGCCTGAACTGGCTACCTTCATCGCCGGTGCGTTGAAAGGTGAAAATGATATCGCT
GTCGGTAATATCATCGGCTCCAACATTTTTAATATTGTGATTGTACTCGGTGTGCCAGCCCTGCTGTCACCCGGTGAGAT
CAATCCCGAGGCTTTCCAGCGTGATTATTGGGTGATGCTCGCGGTCAGTGTGGTGTTCACCCTTCTTTGCCTGGGCCGTA
AACATCGAATCGGTCATCTGGCAGGCGCTCTGTTATTATGTGGGTTTATCACTTATCTTGCGGTGTTGTTTTTTGCTCCC
ATAAGTGCGCTGTAA

Upstream 100 bases:

>100_bases
GGGTAAACAACAAAGAGATTGAAAGTATATTTTTTAATCACTTCTGCCTACGGACAACCTTTGCCAACGCATTGGGATTA
TACCTAATAAAGGACTCTGC

Downstream 100 bases:

>100_bases
AATACATTTCCCTATAAATTTCAATGCTCAGGAAGGCTTGGAGCGAAAGCAACCAACACACCTACAGCGTGAAAGATGAC
GGTAATACCAACATTGGGCG

Product: putative calcium/sodium:proton antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MFLAITLLIIGLVLLVYGADRLVYGAAVLSRSFGVPPLIIGMTIVGIGTSLPELIVSVTAALNGQTDMAVGNVLGSNITN
LLLIVGGAALIRPLIVRSEILRRELPLMLVVTALCGFLLADNHLSRGDGVILLLAAAAFIVLMLKIARLAHAEGNDILTR
EQLSELPQDSSTTVALLWLVLAFIILPLSAKMIIDNATVIARVAGVSELVIGLTVIAIGTSLPELATFIAGALKGENDIA
VGNIIGSNIFNIVIVLGVPALLSPGEINPEAFQRDYWVMLAVSVVFTLLCLGRKHRIGHLAGALLLCGFITYLAVLFFAP
ISAL

Sequences:

>Translated_324_residues
MFLAITLLIIGLVLLVYGADRLVYGAAVLSRSFGVPPLIIGMTIVGIGTSLPELIVSVTAALNGQTDMAVGNVLGSNITN
LLLIVGGAALIRPLIVRSEILRRELPLMLVVTALCGFLLADNHLSRGDGVILLLAAAAFIVLMLKIARLAHAEGNDILTR
EQLSELPQDSSTTVALLWLVLAFIILPLSAKMIIDNATVIARVAGVSELVIGLTVIAIGTSLPELATFIAGALKGENDIA
VGNIIGSNIFNIVIVLGVPALLSPGEINPEAFQRDYWVMLAVSVVFTLLCLGRKHRIGHLAGALLLCGFITYLAVLFFAP
ISAL
>Mature_324_residues
MFLAITLLIIGLVLLVYGADRLVYGAAVLSRSFGVPPLIIGMTIVGIGTSLPELIVSVTAALNGQTDMAVGNVLGSNITN
LLLIVGGAALIRPLIVRSEILRRELPLMLVVTALCGFLLADNHLSRGDGVILLLAAAAFIVLMLKIARLAHAEGNDILTR
EQLSELPQDSSTTVALLWLVLAFIILPLSAKMIIDNATVIARVAGVSELVIGLTVIAIGTSLPELATFIAGALKGENDIA
VGNIIGSNIFNIVIVLGVPALLSPGEINPEAFQRDYWVMLAVSVVFTLLCLGRKHRIGHLAGALLLCGFITYLAVLFFAP
ISAL

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=322, Percent_Identity=60.5590062111801, Blast_Score=338, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 34051; Mature: 34051

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAITLLIIGLVLLVYGADRLVYGAAVLSRSFGVPPLIIGMTIVGIGTSLPELIVSVTA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
ALNGQTDMAVGNVLGSNITNLLLIVGGAALIRPLIVRSEILRRELPLMLVVTALCGFLLA
HHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
DNHLSRGDGVILLLAAAAFIVLMLKIARLAHAEGNDILTREQLSELPQDSSTTVALLWLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHHH
LAFIILPLSAKMIIDNATVIARVAGVSELVIGLTVIAIGTSLPELATFIAGALKGENDIA
HHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEE
VGNIIGSNIFNIVIVLGVPALLSPGEINPEAFQRDYWVMLAVSVVFTLLCLGRKHRIGHL
EHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AGALLLCGFITYLAVLFFAPISAL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLAITLLIIGLVLLVYGADRLVYGAAVLSRSFGVPPLIIGMTIVGIGTSLPELIVSVTA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
ALNGQTDMAVGNVLGSNITNLLLIVGGAALIRPLIVRSEILRRELPLMLVVTALCGFLLA
HHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
DNHLSRGDGVILLLAAAAFIVLMLKIARLAHAEGNDILTREQLSELPQDSSTTVALLWLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHHH
LAFIILPLSAKMIIDNATVIARVAGVSELVIGLTVIAIGTSLPELATFIAGALKGENDIA
HHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEE
VGNIIGSNIFNIVIVLGVPALLSPGEINPEAFQRDYWVMLAVSVVFTLLCLGRKHRIGHL
EHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AGALLLCGFITYLAVLFFAPISAL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]