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The map label for this gene is ytfL [H]

Identifier: 218930540

GI number: 218930540

Start: 3938210

End: 3939541

Strand: Direct

Name: ytfL [H]

Synonym: YPO3526

Alternate gene names: 218930540

Gene position: 3938210-3939541 (Clockwise)

Preceding gene: 218930539

Following gene: 218930542

Centisome position: 84.62

GC content: 46.25

Gene sequence:

>1332_bases
ATGTTAAATAGTATCTTACTGATTCTTTTTTTAATTGCGGTCAGCGCCTTCTTCTCGCTATCAGAGATTTCATTGGCGGC
TTCACGCAAAATTAAACTAAAACTGCTGGCGGACGAGGGCGATACCAACGCCTTACGAGTCCTGAAACTGCAAGAGACGC
CAGGAATGTTCTTCACCGTGGTCCAAATTGGCCTGAATGCTGTCGCCATTCTTGGTGGTATTGTCGGTGATGCCGCTTTC
TCCCCTTCGTTCAAACTCGTTTTTGAGCGTTTTATGGCTCCTGAGTTGGCCGATCAAGCCAGTTTCGTTTGTTCTTTCGT
GTTAGTGACCAGCTTATTTATTCTGTTTGCTGATTTAACCCCGAAACGCATCGGTATGATTTCACCTGAAGCGGTTGCCG
TCCGGATCGTCAACCCAATGCGCTTCTGCCTAATGATCTTCCGCCCATTAGTCTGGTTCTTCAATGGGATGGCAAATCTT
ATCTTCCGCCTATTTAAATTACCCATGGTCCGTAACGATGACATCACTTCCGATGATATCTATGCCGTGGTAGAAGCCGG
TGCGCTCGCCGGAGTGCTACGCAAGCAAGAGCATGAGTTGATTGAAAACGTCTTTGAGCTGGAGTCTCGAACCGTTCCTT
CCTCCATGACTTCACGTGAAAACGTGATTTACTTTGATCTACGGGAAAGCGAAGACAGTATCAAAGATAAAATCTCCACA
CATCCGCACTCAAAATTCCTGGTATGTGATGGCCACATTGACCAAGTGGTGGGTTACGTTGACTCTAAAGACTTGCTGAA
TCGGGTATTAGGTAACCAAAGTCTGGTACTCAGCAGTGGCGTACAAATTCGTTCAGCTCTGATTGTGCCAGATACATTGA
CACTTTCAGAAGCGTTGGAGAGTTTTAAAACCGCGGGTGAAGACTTCGCCGTGATCCTCAACGAATATGCTTTAGTTGTT
GGGATAATTACACTGAATGACGTAATGACCACGTTGATGGGCGATTTAGTTGGCCAAGGGCAGGAAGAGCAAATTGTTGC
CCGCGATGAGAATTCATGGCTGATTGAGGGCGGTACACCGATTGAAGATGTCATGCGCGTACTGCATATCGACGATTTCC
CGCAATCGGGCAATTATGAAACTATCGGCGGCTTTATGATGTATATGCTGCGTAAAATTCCTAAACGAACTGATTTTGTT
AAATATGCGGGTTACAAATTTGAAGTCGTCGATATTGATAGCTACAAGATAGATCAGCTACTGGTGACAAGGCTCAGTGA
CCAGCCAGCGCCAATCCTGCCAAAAGCACCACACGAAAGCAGTGACGCCTAG

Upstream 100 bases:

>100_bases
ATATAATGCCTTAATATTTAAAAGATATACTGAAACAAGATAATTGTGTGACCCTTCCTTATGATCGCCGGCGCTATCGT
CGGTACGACACGGATAGATT

Downstream 100 bases:

>100_bases
CCGCCGCTGATGAATAAATCGTGATCACGGTAAACATAACGGCCCCTGAGTTGGGGCCGTGATTAAATCTGCTCAGGTGG
GCAAATGCCGCTAACAATGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKLLADEGDTNALRVLKLQETPGMFFTVVQIGLNAVAILGGIVGDAAF
SPSFKLVFERFMAPELADQASFVCSFVLVTSLFILFADLTPKRIGMISPEAVAVRIVNPMRFCLMIFRPLVWFFNGMANL
IFRLFKLPMVRNDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRENVIYFDLRESEDSIKDKIST
HPHSKFLVCDGHIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALESFKTAGEDFAVILNEYALVV
GIITLNDVMTTLMGDLVGQGQEEQIVARDENSWLIEGGTPIEDVMRVLHIDDFPQSGNYETIGGFMMYMLRKIPKRTDFV
KYAGYKFEVVDIDSYKIDQLLVTRLSDQPAPILPKAPHESSDA

Sequences:

>Translated_443_residues
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKLLADEGDTNALRVLKLQETPGMFFTVVQIGLNAVAILGGIVGDAAF
SPSFKLVFERFMAPELADQASFVCSFVLVTSLFILFADLTPKRIGMISPEAVAVRIVNPMRFCLMIFRPLVWFFNGMANL
IFRLFKLPMVRNDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRENVIYFDLRESEDSIKDKIST
HPHSKFLVCDGHIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALESFKTAGEDFAVILNEYALVV
GIITLNDVMTTLMGDLVGQGQEEQIVARDENSWLIEGGTPIEDVMRVLHIDDFPQSGNYETIGGFMMYMLRKIPKRTDFV
KYAGYKFEVVDIDSYKIDQLLVTRLSDQPAPILPKAPHESSDA
>Mature_443_residues
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKLLADEGDTNALRVLKLQETPGMFFTVVQIGLNAVAILGGIVGDAAF
SPSFKLVFERFMAPELADQASFVCSFVLVTSLFILFADLTPKRIGMISPEAVAVRIVNPMRFCLMIFRPLVWFFNGMANL
IFRLFKLPMVRNDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRENVIYFDLRESEDSIKDKIST
HPHSKFLVCDGHIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALESFKTAGEDFAVILNEYALVV
GIITLNDVMTTLMGDLVGQGQEEQIVARDENSWLIEGGTPIEDVMRVLHIDDFPQSGNYETIGGFMMYMLRKIPKRTDFV
KYAGYKFEVVDIDSYKIDQLLVTRLSDQPAPILPKAPHESSDA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=23.4210526315789, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1790664, Length=437, Percent_Identity=82.1510297482838, Blast_Score=744, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=239, Percent_Identity=32.2175732217573, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=22.9665071770335, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788119, Length=246, Percent_Identity=26.8292682926829, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786879, Length=261, Percent_Identity=24.1379310344828, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49238; Mature: 49238

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKLLADEGDTNALRVLKLQETPGMFFTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEEEECCCCHHHHH
VQIGLNAVAILGGIVGDAAFSPSFKLVFERFMAPELADQASFVCSFVLVTSLFILFADLT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMISPEAVAVRIVNPMRFCLMIFRPLVWFFNGMANLIFRLFKLPMVRNDDITSDDI
HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRENVIYFDLRESEDSIKDKIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHCC
HPHSKFLVCDGHIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVILNEYALVVGIITLNDVMTTLMGDLVGQGQEEQIVARDENSWLIEGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCC
IEDVMRVLHIDDFPQSGNYETIGGFMMYMLRKIPKRTDFVKYAGYKFEVVDIDSYKIDQL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEECCEEEEEEECCCHHHHHH
LVTRLSDQPAPILPKAPHESSDA
HHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKLLADEGDTNALRVLKLQETPGMFFTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEEEECCCCHHHHH
VQIGLNAVAILGGIVGDAAFSPSFKLVFERFMAPELADQASFVCSFVLVTSLFILFADLT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMISPEAVAVRIVNPMRFCLMIFRPLVWFFNGMANLIFRLFKLPMVRNDDITSDDI
HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRENVIYFDLRESEDSIKDKIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHCC
HPHSKFLVCDGHIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVILNEYALVVGIITLNDVMTTLMGDLVGQGQEEQIVARDENSWLIEGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCC
IEDVMRVLHIDDFPQSGNYETIGGFMMYMLRKIPKRTDFVKYAGYKFEVVDIDSYKIDQL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEECCEEEEEEECCCHHHHHH
LVTRLSDQPAPILPKAPHESSDA
HHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]