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The map label for this gene is hicB [H]

Identifier: 218930022

GI number: 218930022

Start: 3320862

End: 3321293

Strand: Direct

Name: hicB [H]

Synonym: YPO2973

Alternate gene names: 218930022

Gene position: 3320862-3321293 (Clockwise)

Preceding gene: 218930018

Following gene: 218930025

Centisome position: 71.36

GC content: 50.0

Gene sequence:

>432_bases
GTGTTCAGTTACCCCGCCAGTTATACCGTTGATGAAGCCAGTGGCGAATACCATATTCATTATCGTGACTTCCCTGAATT
GAATTCAGTGACCTACTCCCTTGAAGATGTCGAGTTGGAAGCACAGGAGGGGATTAAAAACGGTGTTGCCGCCGAGATGG
AAGAGCGCCGTCTGATCCCTGCCCCCTCAGCGCTGCAGCCGGGTGATATCGCGGTTCATGTCCCTATTCTTGTGCGCCTA
AAAGCTGAATTACACAATGCTATGCTCGCCAGTGATACCCGCAAAGCTGATATGGCCCGCAAGCTCAGTTTGAATGCCGC
CCAAATGGATCGCCTACTGGATGTTTATTACGCTTCTAAAGTAGAAGCACTGGAACAGGCCCTTTATTTATTGGGTTTTG
AGGCTGACGTTACCGTGCGGAAAATCGTCTGA

Upstream 100 bases:

>100_bases
CTCACTACATCATAAGGTCAAGAAAGAAGGGGATTCCCTGGCAGATACCAGTACAATACGGATACCTTCCGTCCTCATTG
CACTCACAGGAGTGAACACC

Downstream 100 bases:

>100_bases
TTGACTTACTGACGATGCTCTCCGCCGCTGGCCCCCAGTCATCAACCTCAACCTCGGAGCGCATCAACGCCCTTTGTCAT
CTCCGATCCTGGGATCATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MFSYPASYTVDEASGEYHIHYRDFPELNSVTYSLEDVELEAQEGIKNGVAAEMEERRLIPAPSALQPGDIAVHVPILVRL
KAELHNAMLASDTRKADMARKLSLNAAQMDRLLDVYYASKVEALEQALYLLGFEADVTVRKIV

Sequences:

>Translated_143_residues
MFSYPASYTVDEASGEYHIHYRDFPELNSVTYSLEDVELEAQEGIKNGVAAEMEERRLIPAPSALQPGDIAVHVPILVRL
KAELHNAMLASDTRKADMARKLSLNAAQMDRLLDVYYASKVEALEQALYLLGFEADVTVRKIV
>Mature_143_residues
MFSYPASYTVDEASGEYHIHYRDFPELNSVTYSLEDVELEAQEGIKNGVAAEMEERRLIPAPSALQPGDIAVHVPILVRL
KAELHNAMLASDTRKADMARKLSLNAAQMDRLLDVYYASKVEALEQALYLLGFEADVTVRKIV

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin preventing effects of the HicA toxin [H]

COG id: COG1598

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HicB antitoxin family [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012287
- InterPro:   IPR005357 [H]

Pfam domain/function: PF03681 UPF0150 [H]

EC number: NA

Molecular weight: Translated: 15999; Mature: 15999

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYPASYTVDEASGEYHIHYRDFPELNSVTYSLEDVELEAQEGIKNGVAAEMEERRLIP
CCCCCCCCEEECCCCEEEEEECCCCCCCCEEEEHHHCEEEHHHCCCCCCHHHHHHCCCCC
APSALQPGDIAVHVPILVRLKAELHNAMLASDTRKADMARKLSLNAAQMDRLLDVYYASK
CCCCCCCCCEEEECCEEEEEHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
VEALEQALYLLGFEADVTVRKIV
HHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MFSYPASYTVDEASGEYHIHYRDFPELNSVTYSLEDVELEAQEGIKNGVAAEMEERRLIP
CCCCCCCCEEECCCCEEEEEECCCCCCCCEEEEHHHCEEEHHHCCCCCCHHHHHHCCCCC
APSALQPGDIAVHVPILVRLKAELHNAMLASDTRKADMARKLSLNAAQMDRLLDVYYASK
CCCCCCCCCEEEECCEEEEEHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
VEALEQALYLLGFEADVTVRKIV
HHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA