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The map label for this gene is hscB [H]

Identifier: 218929952

GI number: 218929952

Start: 3237302

End: 3237826

Strand: Reverse

Name: hscB [H]

Synonym: YPO2893

Alternate gene names: 218929952

Gene position: 3237826-3237302 (Counterclockwise)

Preceding gene: 218929953

Following gene: 218929951

Centisome position: 69.57

GC content: 50.67

Gene sequence:

>525_bases
ATGGATTATTTTACGTTATTCGGGTTGCCGGCTCGCTATTTGATTGACGGCAACCAACTCACCACGCGTTACCAGGAGTT
GCAACGTCAATTCCACCCCGATCGCTTTGCCACCCAGCCCGAGCGTGAGCGTTTGGCCTCAATGCAGCAGGCTGCAACCA
TCAATGATGCTTACCAAACGCTCAAGCACCCGTTAAAACGTGCCGAGTATATGCTATCTTTGCAGGGTTTTGATTTAGGC
AACGAACAACACACTATGCGTGATACCGCGTTTCTGATGGAACAGTTGGAATTACGTGAGGAGCTTGATGCCATTGAGCG
CAAACCCGATGCTGAAACTTTACTGGCTGAATTTAGCCGCCGTGTGGCGCAGATGACAACAACGCGCACGCAGCAAATGG
TTGAGCAACTGGATGCGCAGCTATGGGTGCAGGCAGCGGATACGGTACGCAAATTGCGCTTTCTGGATAAGTTGCAGCAG
CAAGTTGAACAGTTGGAAGAGCGCTTGTTTGACGATTTTGCCTGA

Upstream 100 bases:

>100_bases
TTCCTGCCCCAGATGTTTGTTGCTCTGTTCCGCTCTCTTTTGCCAAAAGGGAGCGAAACAGATCTCAGCTTAGCCATTAC
AACAACTTCCAGAGCATGCT

Downstream 100 bases:

>100_bases
TTCAAATATCTCATTTGATTAATAAAAAACAAATAAAATTCAAGTGATTAATTATTATATTCCCTTAGTAATTGACGTTG
TAGCTAGGTAGCAAGCAAAT

Product: co-chaperone HscB

Products: NA

Alternate protein names: Hsc20 [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLG
NEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQ
QVEQLEERLFDDFA

Sequences:

>Translated_174_residues
MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLG
NEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQ
QVEQLEERLFDDFA
>Mature_174_residues
MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLG
NEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQ
QVEQLEERLFDDFA

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=162, Percent_Identity=28.3950617283951, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1788876, Length=171, Percent_Identity=66.6666666666667, Blast_Score=225, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17541320, Length=146, Percent_Identity=28.7671232876712, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161084223, Length=170, Percent_Identity=24.7058823529412, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20636; Mature: 20636

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQT
CCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQT
CCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA