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The map label for this gene is yccK [H]

Identifier: 218929872

GI number: 218929872

Start: 3138485

End: 3139474

Strand: Direct

Name: yccK [H]

Synonym: YPO2806

Alternate gene names: 218929872

Gene position: 3138485-3139474 (Clockwise)

Preceding gene: 218929871

Following gene: 218929874

Centisome position: 67.44

GC content: 52.63

Gene sequence:

>990_bases
ATGCAAAAACGTTATCTCGGTAAATCCGGACTTGAAGTATCGGCACTGGGTCTGGGCTGTATGGGGCTGAGCTATGGCTA
CGGCCCAGCAACAGATACTCGTCAGGCCGTCGAACTGATCCGCGCGGCCGTTGAGCGTGGTGTGACATTTTTCGATACCG
CCGAAGTGTATGGCCCTTATCTGAATGAAGAGGTTGTCGGCGAAGCCTTAAAACCCTTTCGCGACCAAGTCGTTATTGCC
ACCAAATTTGGTTTTACCTTCGGTGAAGACAATAAACAGCAGATTTTAAACAGCCGCCCAGAGCATATCCGCGAAGCGGT
GGAAGGATCACTGCGTCGACTCAAAACTGACGTGATTGACCTGTTGTATCAACACCGCGTCGACCCTGATGTTCCCATTG
AAGACGTTGCGGGTACCGTGAAAGACTTGATTGCTGAAGGCAAGGTCAAACATTTCGGGCTTTCCGAAGCCGGTGCACAA
ACTATTCGTCGTGCGCATGCTATACAGCCGGTTGCCGCGCTGCAGAGCGAATACTCAATGTGGTGGCGTGAACCTGAACA
GGAGATCCTGCCGCTGCTGGAGGAACTGGGTATTGGCTTTGTGCCGTTCAGCCCGTTAGGTAAAGGCTTCCTGACCGGGG
CCATCAAGGCCGGAGCGACATTCGGTGAGGATGACTTCCGAAGCAAAGTGCCACGTTTTGCCGCAGAGGCTCTTGAAGCC
AATGAAAGGCTCGTGGCCTTGCTGGGTATTCTTGCCGCAGAAAAAGGCGTGACGTCAGCACAAATTGCTCTGGCATGGTT
GTTGGCACAAAAACCTTGGATTGTGCCAATCCCCGGAACCACAAAACTGCATAGGCTGGAGGAGAACCTGGGGGCTGCAG
ATATTACCCTTTCTCAGGATGATATCTGGAATATTACTCAGGCACTTGCAACGGTGAAAATTGTGGGAGAGCGTTATCCT
GCGGCCATGCAGGCTCGAGTGGGTCGTTAA

Upstream 100 bases:

>100_bases
GCAACGAGCGCCTTCTTCTCACATCGCGACCCGGCAATGGTGGAATGGCTGACTGGCCGTAAACTTGATGTCTAAGCCGC
TATAGAAGAGGAGATTATTG

Downstream 100 bases:

>100_bases
TACTTAATTGTAGTCGCTCAAATTTCATCTGGCTTACGATAATCCGTAAGCCAGTTAATCCGAATAACGCAGTGCATCTA
TCATAAGCGCAAAAACAGGT

Product: putative aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQKRYLGKSGLEVSALGLGCMGLSYGYGPATDTRQAVELIRAAVERGVTFFDTAEVYGPYLNEEVVGEALKPFRDQVVIA
TKFGFTFGEDNKQQILNSRPEHIREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAIQPVAALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKAGATFGEDDFRSKVPRFAAEALEA
NERLVALLGILAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAADITLSQDDIWNITQALATVKIVGERYP
AAMQARVGR

Sequences:

>Translated_329_residues
MQKRYLGKSGLEVSALGLGCMGLSYGYGPATDTRQAVELIRAAVERGVTFFDTAEVYGPYLNEEVVGEALKPFRDQVVIA
TKFGFTFGEDNKQQILNSRPEHIREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAIQPVAALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKAGATFGEDDFRSKVPRFAAEALEA
NERLVALLGILAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAADITLSQDDIWNITQALATVKIVGERYP
AAMQARVGR
>Mature_329_residues
MQKRYLGKSGLEVSALGLGCMGLSYGYGPATDTRQAVELIRAAVERGVTFFDTAEVYGPYLNEEVVGEALKPFRDQVVIA
TKFGFTFGEDNKQQILNSRPEHIREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAIQPVAALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKAGATFGEDDFRSKVPRFAAEALEA
NERLVALLGILAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAADITLSQDDIWNITQALATVKIVGERYP
AAMQARVGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=317, Percent_Identity=30.9148264984227, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=31.4102564102564, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=31.3915857605178, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436964, Length=309, Percent_Identity=30.0970873786408, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=30.0970873786408, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=30.0970873786408, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI223718702, Length=295, Percent_Identity=28.4745762711864, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI41152114, Length=296, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI41327764, Length=280, Percent_Identity=30, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789375, Length=331, Percent_Identity=29.607250755287, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787674, Length=298, Percent_Identity=32.2147651006711, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788070, Length=317, Percent_Identity=32.4921135646688, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=26.9230769230769, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788081, Length=306, Percent_Identity=25.8169934640523, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI48994888, Length=292, Percent_Identity=28.7671232876712, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=28.7009063444109, Blast_Score=129, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6323998, Length=319, Percent_Identity=29.7805642633229, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=319, Percent_Identity=28.8401253918495, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=349, Percent_Identity=27.7936962750716, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=287, Percent_Identity=27.5261324041812, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=27.8225806451613, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=321, Percent_Identity=28.0373831775701, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45549126, Length=321, Percent_Identity=27.7258566978193, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24646155, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=26.0089686098655, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36037; Mature: 36037

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRYLGKSGLEVSALGLGCMGLSYGYGPATDTRQAVELIRAAVERGVTFFDTAEVYGPY
CCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
LNEEVVGEALKPFRDQVVIATKFGFTFGEDNKQQILNSRPEHIREAVEGSLRRLKTDVID
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQTIRRAHAIQPVAALQSEYSM
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKAGATFGEDDFRSKVPRFAAEALEA
HHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
NERLVALLGILAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAADITLSQD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEECCC
DIWNITQALATVKIVGERYPAAMQARVGR
HHHHHHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MQKRYLGKSGLEVSALGLGCMGLSYGYGPATDTRQAVELIRAAVERGVTFFDTAEVYGPY
CCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
LNEEVVGEALKPFRDQVVIATKFGFTFGEDNKQQILNSRPEHIREAVEGSLRRLKTDVID
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQTIRRAHAIQPVAALQSEYSM
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKAGATFGEDDFRSKVPRFAAEALEA
HHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
NERLVALLGILAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAADITLSQD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEECCC
DIWNITQALATVKIVGERYPAAMQARVGR
HHHHHHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]