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The map label for this gene is era [H]

Identifier: 218929791

GI number: 218929791

Start: 3047248

End: 3048159

Strand: Direct

Name: era [H]

Synonym: YPO2719

Alternate gene names: 218929791

Gene position: 3047248-3048159 (Clockwise)

Preceding gene: 218929790

Following gene: 218929792

Centisome position: 65.48

GC content: 46.27

Gene sequence:

>912_bases
ATGAGCGAAGTAGAAAAAACGTATTGTGGTTTTATTGCCATTGTAGGGCGCCCGAATGTAGGCAAATCGACCTTACTAAA
TGAGCTGTTGGGGCAAAAAATCTCCATCACCTCACGTAAACCGCAAACCACACGTCACCGTATTATGGGGATCCACACTG
AAGGGCCTTATCAGGCTATTTATGTTGATACCCCTGGGCTGCATATTGAAGAAAAGCGTGCCATTAACCGCTTAATGAAT
CGGGCGGCAAGTAGCTCTCTTGGTGATGTGGAATTAGTCATTTTTGTGGTTGAAGGTACTCATTGGACTGCTGATGACGA
GATGGTGGTTAATAAGCTGCGCAGTTTGCAATGCCCGGTATTATTGGCCATCAACAAAGTGGATAACGTAACGGATAAAA
CCAAGTTATTACCGCATATGCAGTTCCTTAGCCAGCAGATGAACTTCCTGGACGTTGTGCCAATCTCAGCTGAGAAGGGA
ATGAATGTTGATACCATCGCCAGCATTGTGCGCAAGCATATGCCGGAAGCTGAACATCACTTCCCAGAGGATTACATCAC
TGACCGTTCCCAGCGTTTTATGGCGTCGGAAATTATTCGTGAAAAGTTGATGCGTTTCCTGGGCGAAGAACTGCCTTATT
CGGTGACGGTTGAGATTGAGCAGTTCGTGCCGAATGAACGTGGTGGCTATAATATCCATGGTCTGATTTTGGTTGAGCGC
GAAGGCCAAAAGAAAATGGTTATCGGCAACAAAGGCAGCAAAATCAAAGTAATCGGTACCGAAGCCCGTCAGGACATGGA
GCGGATGTTTGAAGCTAAAGTGCATCTTGAACTGTGGGTGAAAGTGAAATCAGGCTGGGCAGATGACGAACGTGCATTGC
GCAGCTTAGGCTATACCGACGATTTGAAATAA

Upstream 100 bases:

>100_bases
AGGTGAGTGGCTTGAATGAACCAGTAATAGGTACTGGCTCAAGCCGTCGTAAAGCTGAGCAGGCGGCAGCGGAACAAGCG
CTGAAACAGTTGGAGCTTGA

Downstream 100 bases:

>100_bases
GGCTTGCCGATGGACGGTTGGCAACGCGCATTTGTTCTGCATGGGCGGCCTTACAGTGAAACCAGCTTAATGCTGGATTT
ATTTACTGAAGGGGAAGGGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMN
RAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKG
MNVDTIASIVRKHMPEAEHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVER
EGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK

Sequences:

>Translated_303_residues
MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMN
RAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKG
MNVDTIASIVRKHMPEAEHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVER
EGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK
>Mature_302_residues
SEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNR
AASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKGM
NVDTIASIVRKHMPEAEHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVERE
GQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=321, Percent_Identity=27.1028037383178, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=84.9498327759197, Blast_Score=540, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24646434, Length=302, Percent_Identity=24.1721854304636, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34473; Mature: 34342

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAI
CCCHHHHHCCEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEECCCCEEEE
YVDTPGLHIEEKRAINRLMNRAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPV
EEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCEECCCHHHHHHHHHHCCCCE
LLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKGMNVDTIASIVRKHMPEAEHH
EEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHC
FPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVER
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCEEEEEEEEEEE
EGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTD
CCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCCC
DLK
CCC
>Mature Secondary Structure 
SEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAI
CCHHHHHCCEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEECCCCEEEE
YVDTPGLHIEEKRAINRLMNRAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPV
EEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCEECCCHHHHHHHHHHCCCCE
LLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKGMNVDTIASIVRKHMPEAEHH
EEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHC
FPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVER
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCEEEEEEEEEEE
EGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTD
CCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCCC
DLK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA