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The map label for this gene is cpdP

Identifier: 218929769

GI number: 218929769

Start: 3024080

End: 3025111

Strand: Direct

Name: cpdP

Synonym: YPO2696

Alternate gene names: 218929769

Gene position: 3024080-3025111 (Clockwise)

Preceding gene: 218929768

Following gene: 218929770

Centisome position: 64.98

GC content: 47.19

Gene sequence:

>1032_bases
TTGAAATATCTCTCGATTAAATCTGCATCAGATAAGATAAAGAGTGGTCTGCTAAAGACGGGCGTGATTTTATCTTTCAG
TCTCTTCAGTTCACTGTCCACTGCGGCTTTTGAGGTCGTGGCGCTTGGCGTTGATGGGGGTGTCAGTGATGGTAATCTGA
CCTCTTATCTGATTCGCAATGATAGCCAGCCGCTGTATTTGGGGCTGGATGCCGGTTCCGTGTTGCCAGGGATCGCTCGT
GCCTTGGAGAAAGGCCATTTTGCAGCGATCACCGATGCCATGGCCGCTCCGCTAACCCGGCAGGGCTATATTTTTCGCCA
GAGCATTAACAGTTATTTTATTAGCCATGCGCATTTAGATCATGTCTCTGGCCTGATTATCGGTTCACCGGATGACAGCA
AGAAAACCATTTATGCTTCGGCTGATACCATTGATGTGCTGAGAAACTACTATTTTAACTGGCGCGTTTGGCCCAATTTT
ACCGACAGCGGCAGTGGGGCTCGTTTAGGGACTTACCGTATGCAAGTGGTGCGCCCGGCTCAGTCTTTGAGCTTGGGGTT
GACCCGCTTAACGGGGGAAATGTATCCACTGAGTCATGATAAATCGCCCTCATCCATGCTGCTTATCAGTAGTAATAATG
AGTTCTTTGCCTATTTCGGTGATACCGGCCCGGATGATGTCGAAAAATCCAAAAATCTGGATACGGTCTGGCGCAAACTG
GCGGAGAAGGTTACACAACAACAACTGAAAGGGATGATTATTGAGGTCTCGTATCCTAATGATGTGGCAGACAATAAGTT
GTTTGGCCACATGACACCAACGTGGTTGTTGAAAGAATTGAAAAAACTGGAGCAATACAGTGGGGAAGGCCAGCCACTAA
AAGGATTACCGGTGGTGATTAGCCACATAAAACCCTCATTCCAGCAGGGGCAGGATGTGCGTAAATTAATTCTCTCTGAG
TTGCAACAAGGCAATGATATGGGAATCGAATTTATCCTGATGGAACAAGGTGATAGCCAGAAATTCCAGTGA

Upstream 100 bases:

>100_bases
TGGTTGATCACAAGCAAGCCAGATTGGCTACACTCGCGGCATTTGAAGCCGCTAAGCGGGATAGCACAAGGATCCCTAAT
CGCAAGGAGCCTTCATGTTA

Downstream 100 bases:

>100_bases
CTTGCGGTTGGCTTTTCTTTTATAGGATGAAAATAGCTATATGACGAAAATAGCTAGGTGACAAAAATAGTCCCCGCGCT
GTATTTATACTGATTAATTG

Product: putative 3',5'-cyclic-nucleotide phosphodiesterase

Products: NA

Alternate protein names: 3':5'-CNP; PDEase

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRNDSQPLYLGLDAGSVLPGIAR
ALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNF
TDSGSGARLGTYRMQVVRPAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKL
AEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVISHIKPSFQQGQDVRKLILSE
LQQGNDMGIEFILMEQGDSQKFQ

Sequences:

>Translated_343_residues
MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRNDSQPLYLGLDAGSVLPGIAR
ALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNF
TDSGSGARLGTYRMQVVRPAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKL
AEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVISHIKPSFQQGQDVRKLILSE
LQQGNDMGIEFILMEQGDSQKFQ
>Mature_343_residues
MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRNDSQPLYLGLDAGSVLPGIAR
ALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNF
TDSGSGARLGTYRMQVVRPAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKL
AEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVISHIKPSFQQGQDVRKLILSE
LQQGNDMGIEFILMEQGDSQKFQ

Specific function: Unknown

COG id: COG5212

COG function: function code T; Low-affinity cAMP phosphodiesterase

Gene ontology:

Cell location: Periplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cAMP phosphodiesterase class-II family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321189, Length=304, Percent_Identity=25.9868421052632, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CPDP_YERPE (Q8ZD92)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AH0328
- RefSeq:   NP_668594.1
- RefSeq:   NP_993822.1
- RefSeq:   YP_002347644.1
- ProteinModelPortal:   Q8ZD92
- GeneID:   1146218
- GeneID:   1175526
- GeneID:   2764764
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2696
- KEGG:   ypk:y1271
- KEGG:   ypm:YP_2500
- HOGENOM:   HBG303327
- OMA:   LYFGDTG
- ProtClustDB:   CLSK889264
- BioCyc:   YPES187410:Y1271-MONOMER
- BioCyc:   YPES214092:YPO2696-MONOMER
- BRENDA:   3.1.4.17
- InterPro:   IPR000396
- PIRSF:   PIRSF000962
- PRINTS:   PR00388

Pfam domain/function: PF02112 PDEase_II

EC number: =3.1.4.17

Molecular weight: Translated: 37875; Mature: 37875

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00607 PDEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRN
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCEEEEEEEC
DSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLD
CCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
HVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVRPA
HHCEEEEECCCCCCEEEEECCHHHHHHHHCEEEEEECCCCCCCCCCCEEEHEEEEEECCH
QSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKL
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHCCCHHHHHHHH
AEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVI
HHHHHHHHHCCEEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
SHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
HHCCCCHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRN
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCEEEEEEEC
DSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLD
CCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
HVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVRPA
HHCEEEEECCCCCCEEEEECCHHHHHHHHCEEEEEECCCCCCCCCCCEEEHEEEEEECCH
QSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKL
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHCCCHHHHHHHH
AEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVI
HHHHHHHHHCCEEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
SHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
HHCCCCHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430