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The map label for this gene is gltK [H]

Identifier: 218929694

GI number: 218929694

Start: 2935097

End: 2935771

Strand: Reverse

Name: gltK [H]

Synonym: YPO2613

Alternate gene names: 218929694

Gene position: 2935771-2935097 (Counterclockwise)

Preceding gene: 218929695

Following gene: 218929693

Centisome position: 63.08

GC content: 48.3

Gene sequence:

>675_bases
ATGTACGAATTTGATTGGAGTTCCATCGCCCCCAGCCTGCCCTATCTGCTGCAAGGCTTGATTGTAACTGTCAAAATAAC
CCTCATCGCCATTGTGTTCGGGATCCTCTGGGGAACAATTTTGGCAGTGATGCGTCTGTCACCGATTAAAGCCATCAGCT
GGTTTGCAACTGCTTATGTTAACGTGTTCCGCTCTATTCCGTTGGTCATGGTGCTGTTGTGGTTTTATTTAGTGGTGCCA
GGCTTCTTACAAAATGTGCTGGGCTTATCACCAAAAACTGATATTCGGTTGATCTCAGCCATGGTAGCCTTTTCGCTGTT
CGAAGCCGCCTATTACTCGGAAATTATCCGGGCCGGGATCCAAAGTATTTCTCGTGGGCAATCCTCTGCGGCATTGGCGT
TAGGGATGACTCAGGGTCAATCAATGAGACTGGTTATCCTGCCACAAGCTTTCCGGGCCATGGTGCCGCTACTGTTAACT
CAGGGGATAGTATTATTCCAGGATACGTCACTGGTATATGTCCTTAGCCTGGCCGATTTCTTCCGTACAGCCACCACCAT
CGGCGAACGGGACGGCACGCAGGTCGAAATGGTACTGTTTGCCGGTTTAGTTTATTTCGTTATCAGCATTTCCGCGTCAA
TGCTGGTTAACTATTTGAAGAAAAGGACTGTTTGA

Upstream 100 bases:

>100_bases
CCATCACCCTAGGTTATGTACTGATCAATGCCGTGATCATGCTGTTAATGCGCTTAGTTGAAAAGAAAGTGCAATTACCC
GGCAATCTGGGGAGTAAATA

Downstream 100 bases:

>100_bases
TGATTTCCCTGAAGAATGTTTCTAAATGGTATGGTCAATTTCAGGTGCTGGCTGACTGTACTACTGAAGTCAAAAAAGGT
GAGGTAGTCGTCGTTTGTGG

Product: putative glutamate/aspartate transport system permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MYEFDWSSIAPSLPYLLQGLIVTVKITLIAIVFGILWGTILAVMRLSPIKAISWFATAYVNVFRSIPLVMVLLWFYLVVP
GFLQNVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIQSISRGQSSAALALGMTQGQSMRLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTATTIGERDGTQVEMVLFAGLVYFVISISASMLVNYLKKRTV

Sequences:

>Translated_224_residues
MYEFDWSSIAPSLPYLLQGLIVTVKITLIAIVFGILWGTILAVMRLSPIKAISWFATAYVNVFRSIPLVMVLLWFYLVVP
GFLQNVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIQSISRGQSSAALALGMTQGQSMRLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTATTIGERDGTQVEMVLFAGLVYFVISISASMLVNYLKKRTV
>Mature_224_residues
MYEFDWSSIAPSLPYLLQGLIVTVKITLIAIVFGILWGTILAVMRLSPIKAISWFATAYVNVFRSIPLVMVLLWFYLVVP
GFLQNVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIQSISRGQSSAALALGMTQGQSMRLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTATTIGERDGTQVEMVLFAGLVYFVISISASMLVNYLKKRTV

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=223, Percent_Identity=86.0986547085202, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1788226, Length=211, Percent_Identity=39.8104265402844, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786874, Length=217, Percent_Identity=31.3364055299539, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787030, Length=220, Percent_Identity=30, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=34.4262295081967, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=25.8064516129032, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=24.6445497630332, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788645, Length=224, Percent_Identity=25, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787086, Length=216, Percent_Identity=23.6111111111111, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24794; Mature: 24794

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEFDWSSIAPSLPYLLQGLIVTVKITLIAIVFGILWGTILAVMRLSPIKAISWFATAYV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
NVFRSIPLVMVLLWFYLVVPGFLQNVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSISRGQSSAALALGMTQGQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHHCCCCHHHHHEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTATTIGERDGTQVEMVLFAGLVYFVISISASMLVNYLKKRTV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYEFDWSSIAPSLPYLLQGLIVTVKITLIAIVFGILWGTILAVMRLSPIKAISWFATAYV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
NVFRSIPLVMVLLWFYLVVPGFLQNVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSISRGQSSAALALGMTQGQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHHCCCCHHHHHEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTATTIGERDGTQVEMVLFAGLVYFVISISASMLVNYLKKRTV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]