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The map label for this gene is ybhA [H]

Identifier: 218928312

GI number: 218928312

Start: 1293405

End: 1294226

Strand: Reverse

Name: ybhA [H]

Synonym: YPO1148

Alternate gene names: 218928312

Gene position: 1294226-1293405 (Counterclockwise)

Preceding gene: 218928314

Following gene: 218928307

Centisome position: 27.81

GC content: 52.07

Gene sequence:

>822_bases
ATGACATATCGCATAATCGCACTGGATCTGGACGGAACACTGTTAGATCACAAAAAACGCATCCTGCCTGAATCGTTGTC
CGCGCTGGCGCAAGCCCGGGCTGAAGGCGTGAAAGTGATCGTCGTAACAGGCCGCCACCATGTCGCGATCCATCCGTTTT
ATCAGGCACTGCAACTGGATACACCCGCTATCTGCTGTAACGGCACTTATATTTATGATTATCAAAATAAAAAAGTGCTG
GATTCAAACCCACTCACTCCACAACAGGCGGTTCAAGTCCTGCAATTACTGGAGAAAACACAGATCCATGGCCTGATGTA
TGTGGATGATGCCATGCTGTATCAGCAGATCACGGGCCATGTGACCCGCACCCTCAGTTGGGCCGAGTCATTGCCGCCCG
CTCAGCGCCCGACCTTTCTTCAGGTCAACAGCTTACTGGATGCCGCTCACAGTGCGACCGCCATCTGGAAATTTGCAACC
TCTCACCCAGATACTGCACAGTTAAAAGCGTTTGCCGCCAGGGTAGAAGCAGAAATGGGTCTGGCCTGCGAATGGTCGTG
GCATGATCAGGTGGATATCGCCCAAGCGGGGAACAGCAAGGGGAAACGCCTCCAACAGTGGGTTGAATCTCAGGGCCTGA
GTATGCAAGAGGTGATCGCTTTTGGTGATAACTTTAACGATCTGAGTATGTTAGAGGCTGCTGGATTAGGGGTTGCCATG
GGTAACAGCGACGATGCGATTAAACAACGGGCGGACCTGGTGATTACAGATAACGAGCAACCGGGTATTGCCGCCGTTAT
CCGCCAGCATGTATTAGCCTGA

Upstream 100 bases:

>100_bases
CCGGTTTGGTTTAATCGATCACCCATCCGGTGTACTATCGGAACATACTTTTCAAGCATATAATTTCTCATTCGCCCCTT
TAATGGGGACAGGGACCGCT

Downstream 100 bases:

>100_bases
TAAATTCACAGCGACAGATTCATCATGGTGGTGCCTACACAAAAAGCGGCACCACTCAATCTGGTACAGGGCCATTCTGG
CGGTTAAATGACACACTTTT

Product: phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTYRIIALDLDGTLLDHKKRILPESLSALAQARAEGVKVIVVTGRHHVAIHPFYQALQLDTPAICCNGTYIYDYQNKKVL
DSNPLTPQQAVQVLQLLEKTQIHGLMYVDDAMLYQQITGHVTRTLSWAESLPPAQRPTFLQVNSLLDAAHSATAIWKFAT
SHPDTAQLKAFAARVEAEMGLACEWSWHDQVDIAQAGNSKGKRLQQWVESQGLSMQEVIAFGDNFNDLSMLEAAGLGVAM
GNSDDAIKQRADLVITDNEQPGIAAVIRQHVLA

Sequences:

>Translated_273_residues
MTYRIIALDLDGTLLDHKKRILPESLSALAQARAEGVKVIVVTGRHHVAIHPFYQALQLDTPAICCNGTYIYDYQNKKVL
DSNPLTPQQAVQVLQLLEKTQIHGLMYVDDAMLYQQITGHVTRTLSWAESLPPAQRPTFLQVNSLLDAAHSATAIWKFAT
SHPDTAQLKAFAARVEAEMGLACEWSWHDQVDIAQAGNSKGKRLQQWVESQGLSMQEVIAFGDNFNDLSMLEAAGLGVAM
GNSDDAIKQRADLVITDNEQPGIAAVIRQHVLA
>Mature_272_residues
TYRIIALDLDGTLLDHKKRILPESLSALAQARAEGVKVIVVTGRHHVAIHPFYQALQLDTPAICCNGTYIYDYQNKKVLD
SNPLTPQQAVQVLQLLEKTQIHGLMYVDDAMLYQQITGHVTRTLSWAESLPPAQRPTFLQVNSLLDAAHSATAIWKFATS
HPDTAQLKAFAARVEAEMGLACEWSWHDQVDIAQAGNSKGKRLQQWVESQGLSMQEVIAFGDNFNDLSMLEAAGLGVAMG
NSDDAIKQRADLVITDNEQPGIAAVIRQHVLA

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=272, Percent_Identity=63.9705882352941, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI87081741, Length=240, Percent_Identity=27.5, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 30080; Mature: 29948

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRIIALDLDGTLLDHKKRILPESLSALAQARAEGVKVIVVTGRHHVAIHPFYQALQLD
CEEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHHCCEEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYIYDYQNKKVLDSNPLTPQQAVQVLQLLEKTQIHGLMYVDDAMLYQQITGH
CCEEEECCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHH
VTRTLSWAESLPPAQRPTFLQVNSLLDAAHSATAIWKFATSHPDTAQLKAFAARVEAEMG
HHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCC
LACEWSWHDQVDIAQAGNSKGKRLQQWVESQGLSMQEVIAFGDNFNDLSMLEAAGLGVAM
EEEEECCCCCEEHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHCCCEEEE
GNSDDAIKQRADLVITDNEQPGIAAVIRQHVLA
CCCCHHHHHCCCEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TYRIIALDLDGTLLDHKKRILPESLSALAQARAEGVKVIVVTGRHHVAIHPFYQALQLD
EEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHHCCEEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYIYDYQNKKVLDSNPLTPQQAVQVLQLLEKTQIHGLMYVDDAMLYQQITGH
CCEEEECCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHH
VTRTLSWAESLPPAQRPTFLQVNSLLDAAHSATAIWKFATSHPDTAQLKAFAARVEAEMG
HHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCC
LACEWSWHDQVDIAQAGNSKGKRLQQWVESQGLSMQEVIAFGDNFNDLSMLEAAGLGVAM
EEEEECCCCCEEHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHCCCEEEE
GNSDDAIKQRADLVITDNEQPGIAAVIRQHVLA
CCCCHHHHHCCCEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]