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The map label for this gene is pnuC [H]

Identifier: 218928296

GI number: 218928296

Start: 1274876

End: 1275601

Strand: Direct

Name: pnuC [H]

Synonym: YPO1128

Alternate gene names: 218928296

Gene position: 1274876-1275601 (Clockwise)

Preceding gene: 218928295

Following gene: 218928308

Centisome position: 27.39

GC content: 46.14

Gene sequence:

>726_bases
ATGGATTTTCTCAGCACAGGCAACATATTGGTACATATACCGCTGGGGGCGGGCGGTTACGATCTTTCATGGATAGAGGC
AATTGGTACCCTATTCGGGTTGCTTTGTATCTGGTTTGCCAGCAAAGAAAAGATCATCAACTACTTATTTGGTCTGATTA
ACGTGACATTGTTCGCCGTGATCTTCTTTCAGATCCAACTCTACGCCAGCTTGTTATTACAGTTGTTTTTCTTTGGTGCC
AATATTTACGGCTGGTATGCCTGGAGCAAACAAACACCGGATAATCAGGCTGAATTAAAGATTCGCTGGTTATCCTTGCC
TAAAGCATTGGCTTGGGCTGCAGTTTGTATTGCTGGCATCGTATTAATGACATTGCATATTGATACCGTATTTGCCTGGT
TGACACGTGTAGCAGTGACGGTGATGCAGAGTCTGGGGGCGAATGTACAGATGCCAGAGTTGCAACCTGATGCTTTCCCA
TTCTGGGACTCGACGATGATGGTCTTGTCTATTGCTGCCATGATCCTCATGACCCGCAAATACGTAGAGAACTGGCTGAT
TTGGGTCGTTATTGATGTCATCAGTGTGGCGATCTTTGCCTATCAGGGGGTTTATGCCATGGCGCTGGAGTATGCGTTCC
TGACCCTTATTGCATTGAACGGTTCTTGGTTGTGGATCAAGAGTGCTGCACGAAATCATTCACGCCCACTGTCTACTCAA
GGTTAA

Upstream 100 bases:

>100_bases
TCGGCGCCTCTTGGCGTCGTGAATAATCACCTATCATGAGATGAGCAAGAGACTTTTATTTTAATAAATCAGTTCTATCG
GCAGCTAAAAGGATCACCAG

Downstream 100 bases:

>100_bases
TAACGACTCGGCTCACCTGCGGGATAGCATAAATACGGTTCAAATCAGTTCCTGATTCGGTTTCGTTTACTGCCTGCAGC
AACAATAACTTTGGGTATAT

Product: intergral membrane NMN transport protein PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MDFLSTGNILVHIPLGAGGYDLSWIEAIGTLFGLLCIWFASKEKIINYLFGLINVTLFAVIFFQIQLYASLLLQLFFFGA
NIYGWYAWSKQTPDNQAELKIRWLSLPKALAWAAVCIAGIVLMTLHIDTVFAWLTRVAVTVMQSLGANVQMPELQPDAFP
FWDSTMMVLSIAAMILMTRKYVENWLIWVVIDVISVAIFAYQGVYAMALEYAFLTLIALNGSWLWIKSAARNHSRPLSTQ
G

Sequences:

>Translated_241_residues
MDFLSTGNILVHIPLGAGGYDLSWIEAIGTLFGLLCIWFASKEKIINYLFGLINVTLFAVIFFQIQLYASLLLQLFFFGA
NIYGWYAWSKQTPDNQAELKIRWLSLPKALAWAAVCIAGIVLMTLHIDTVFAWLTRVAVTVMQSLGANVQMPELQPDAFP
FWDSTMMVLSIAAMILMTRKYVENWLIWVVIDVISVAIFAYQGVYAMALEYAFLTLIALNGSWLWIKSAARNHSRPLSTQ
G
>Mature_241_residues
MDFLSTGNILVHIPLGAGGYDLSWIEAIGTLFGLLCIWFASKEKIINYLFGLINVTLFAVIFFQIQLYASLLLQLFFFGA
NIYGWYAWSKQTPDNQAELKIRWLSLPKALAWAAVCIAGIVLMTLHIDTVFAWLTRVAVTVMQSLGANVQMPELQPDAFP
FWDSTMMVLSIAAMILMTRKYVENWLIWVVIDVISVAIFAYQGVYAMALEYAFLTLIALNGSWLWIKSAARNHSRPLSTQ
G

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=238, Percent_Identity=76.0504201680672, Blast_Score=350, Evalue=5e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27146; Mature: 27146

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLSTGNILVHIPLGAGGYDLSWIEAIGTLFGLLCIWFASKEKIINYLFGLINVTLFAV
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFGANIYGWYAWSKQTPDNQAELKIRWLSLPKALAWAAVCIAGI
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHEEEEEECCHHHHHHHHHHHHHH
VLMTLHIDTVFAWLTRVAVTVMQSLGANVQMPELQPDAFPFWDSTMMVLSIAAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YVENWLIWVVIDVISVAIFAYQGVYAMALEYAFLTLIALNGSWLWIKSAARNHSRPLSTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCCCC
G
C
>Mature Secondary Structure
MDFLSTGNILVHIPLGAGGYDLSWIEAIGTLFGLLCIWFASKEKIINYLFGLINVTLFAV
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFGANIYGWYAWSKQTPDNQAELKIRWLSLPKALAWAAVCIAGI
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHEEEEEECCHHHHHHHHHHHHHH
VLMTLHIDTVFAWLTRVAVTVMQSLGANVQMPELQPDAFPFWDSTMMVLSIAAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YVENWLIWVVIDVISVAIFAYQGVYAMALEYAFLTLIALNGSWLWIKSAARNHSRPLSTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]