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The map label for this gene is nadA [H]

Identifier: 218928295

GI number: 218928295

Start: 1273693

End: 1274754

Strand: Direct

Name: nadA [H]

Synonym: YPO1127

Alternate gene names: 218928295

Gene position: 1273693-1274754 (Clockwise)

Preceding gene: 218928294

Following gene: 218928296

Centisome position: 27.37

GC content: 50.75

Gene sequence:

>1062_bases
ATGAGCGAAATTTTTGATGTGAATGCGGCTATTTATCCTTTCCCGGCGCGGCCTGTTCCGTTGGACACCAATGAAAAAGC
TTTTTATCGTGAGAAAATAAAAACACTGTTAAAGCAACGCGACGCAGTGTTAGTCGCTCACTATTACACTGATCCCGAAA
TTCAGGCACTGGCCGAAGAGACGGGGGGCTGTGTCGCCGACTCACTTGAAATGGCTCGTTTTGGCAATAATCACCCGGCA
TCAACGCTACTGGTTGCTGGTGTACGTTTTATGGGGGAAACCGCCAAAATTCTCAATCCAGAGAAAAAAGTGTTAATGCC
AACTCTGAATGCGGAATGTTCACTGGATTTAGGATGCCCGGTTGATGAGTTTACCGCATTTTGTGACAGCCATCCGGATC
GCACCGTGGTGGTGTACGCCAACACCTCAGCGGCAGTAAAAGCCAAGGCGGATTGGGTTGTAACGTCCAGTATTGCGGTT
GAATTAATTGAGCATCTCGATAGCTTGGGCGAGAAAATTATTTGGGCACCTGATCGCCATTTGGGCAGCTACGTACAGAA
GAAGAGTGGTGCCGATGTATTGTGCTGGCAGGGGGCCTGTATCGTCCATGACGAGTTTAAAACTCAGGCGCTGGCCCGGA
TGAAAGCGTTATACCCTGATGCCGCTGTGTTGGTCCACCCAGAGTCACCACAGGCGGTGGTGGATATGGCTGATGCCGTT
GGGTCGACCAGTCAACTGATCCAAGCGGCGAAGACACTGCCGCAGAAAACGTTAATTGTTGCCACCGATCGGGGCATTTT
TTACAAGATGCAGCAGGCCTGCCCGGATAAAGAGTTGTTTGAAGCACCTACTGCAGGTGAAGGGGCGACATGCCGCAGTT
GTGCCCATTGTCCATGGATGGCGATGAATGGCCTCCGAGCAATCGCTGAAGGGCTGGAGCAGGGTGGGGTGATGCATGAG
ATACATGTCGATGAAGAATTGCGTCAGCAGGCGCTGATACCGTTAAATCGCATGCTGGATTTTGCCAATCAATTGAAGTT
ACAGGTCAAAGGCAATGCCTGA

Upstream 100 bases:

>100_bases
TATTTTGTTTAGGATAAAAAACAAATCAATTCAATTCTTACTGGGTGGCTAGCAGCGATCTGATAGCTTCAGTAATACCA
CAGCAACAGAGATGTGAGCG

Downstream 100 bases:

>100_bases
GTAACTGGTGAGAATATTCATTCGGCGCCTCTTGGCGTCGTGAATAATCACCTATCATGAGATGAGCAAGAGACTTTTAT
TTTAATAAATCAGTTCTATC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPA
STLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCPVDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAV
ELIEHLDSLGEKIIWAPDRHLGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAV
GSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWMAMNGLRAIAEGLEQGGVMHE
IHVDEELRQQALIPLNRMLDFANQLKLQVKGNA

Sequences:

>Translated_353_residues
MSEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPA
STLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCPVDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAV
ELIEHLDSLGEKIIWAPDRHLGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAV
GSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWMAMNGLRAIAEGLEQGGVMHE
IHVDEELRQQALIPLNRMLDFANQLKLQVKGNA
>Mature_352_residues
SEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPAS
TLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCPVDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAVE
LIEHLDSLGEKIIWAPDRHLGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAVG
STSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWMAMNGLRAIAEGLEQGGVMHEI
HVDEELRQQALIPLNRMLDFANQLKLQVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=346, Percent_Identity=82.0809248554913, Blast_Score=612, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38594; Mature: 38462

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEE
CCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHH
TGGCVADSLEMARFGNNHPASTLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCHHEEEEECCCCEEEECCCC
VDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAVELIEHLDSLGEKIIWAPDRH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCEEEECCCHH
LGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAV
HHHHHHHCCCCCEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHC
GSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLRAIAEGLEQGGVMHEIHVDEELRQQALIPLNRMLDFANQLKLQVKGNA
HHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCCCHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure 
SEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEE
CCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHH
TGGCVADSLEMARFGNNHPASTLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCHHEEEEECCCCEEEECCCC
VDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAVELIEHLDSLGEKIIWAPDRH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCEEEECCCHH
LGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAV
HHHHHHHCCCCCEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHC
GSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLRAIAEGLEQGGVMHEIHVDEELRQQALIPLNRMLDFANQLKLQVKGNA
HHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCCCHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA