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The map label for this gene is tolR [H]

Identifier: 218928290

GI number: 218928290

Start: 1268363

End: 1268791

Strand: Direct

Name: tolR [H]

Synonym: YPO1122

Alternate gene names: 218928290

Gene position: 1268363-1268791 (Clockwise)

Preceding gene: 218928289

Following gene: 218928291

Centisome position: 27.25

GC content: 46.85

Gene sequence:

>429_bases
ATGGCGCGAGTACGTGGTCGTAAGCGTCGCGAGCTTAAGTCTGAAATTAATATTGTTCCCTTACTCGACGTTTTGCTGGT
GTTGTTGTTGATATTCATGGCAACCGCACCCATTATCACGCAAAGTGTCGAGGTAAACTTGCCAGATGCGACGGATTCAA
AAACGGTATCCAGTGATGATAATCCGCCTGTAATTGTTGAGGTTTCCGGTGTTGGGCAATATACAGTAGTCGTTGATCAC
CAACGGATGGAGCTGTTGCCTTCAGAGCAAGTGGTGGCAGAAGCTCAAGCACGATTAAAAACGAATCCGAAAACCGTGTT
CCTGATCGGTGGCGCAAAAGAGGTGCCTTATGATGAAATTATTAAGGCGCTGAATATGCTGCATCAGGCGGGTGTTACAT
CGGTGGGCTTAATGACCCAACCGATATAA

Upstream 100 bases:

>100_bases
TAAGCTTGAACAAAACTATGACAACTTCATGGAAGAGTTCATTGCTATTCTGCATCGCCAGGCTTTCGCCAGCACCGAAA
GCAAATAAGTAGGGGGTTAT

Downstream 100 bases:

>100_bases
ATTTGCGTTGATATTGGTTGGGCTAATCGTTAGCTCAACCCGTAGATACCCTGTTTTTAGCAGTTCCGTTTTTTAGCAAT
AGAGCGCGGACATCGAGTGT

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MARVRGRKRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVNLPDATDSKTVSSDDNPPVIVEVSGVGQYTVVVDH
QRMELLPSEQVVAEAQARLKTNPKTVFLIGGAKEVPYDEIIKALNMLHQAGVTSVGLMTQPI

Sequences:

>Translated_142_residues
MARVRGRKRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVNLPDATDSKTVSSDDNPPVIVEVSGVGQYTVVVDH
QRMELLPSEQVVAEAQARLKTNPKTVFLIGGAKEVPYDEIIKALNMLHQAGVTSVGLMTQPI
>Mature_141_residues
ARVRGRKRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVNLPDATDSKTVSSDDNPPVIVEVSGVGQYTVVVDHQ
RMELLPSEQVVAEAQARLKTNPKTVFLIGGAKEVPYDEIIKALNMLHQAGVTSVGLMTQPI

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=132, Percent_Identity=83.3333333333333, Blast_Score=196, Evalue=4e-52,
Organism=Escherichia coli, GI1789380, Length=126, Percent_Identity=31.7460317460317, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15510; Mature: 15379

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVRGRKRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVNLPDATDSKTVSSDD
CCCCCCHHHHHHHHHCCEECHHHHHHHHHHHHHHHCCHHCCEEEEECCCCCCCCCCCCCC
NPPVIVEVSGVGQYTVVVDHQRMELLPSEQVVAEAQARLKTNPKTVFLIGGAKEVPYDEI
CCCEEEEECCCCEEEEEECCHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
IKALNMLHQAGVTSVGLMTQPI
HHHHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure 
ARVRGRKRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVNLPDATDSKTVSSDD
CCCCCHHHHHHHHHCCEECHHHHHHHHHHHHHHHCCHHCCEEEEECCCCCCCCCCCCCC
NPPVIVEVSGVGQYTVVVDHQRMELLPSEQVVAEAQARLKTNPKTVFLIGGAKEVPYDEI
CCCEEEEECCCCEEEEEECCHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
IKALNMLHQAGVTSVGLMTQPI
HHHHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]