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The map label for this gene is rof [H]

Identifier: 218928232

GI number: 218928232

Start: 1208118

End: 1208378

Strand: Reverse

Name: rof [H]

Synonym: YPO1064

Alternate gene names: 218928232

Gene position: 1208378-1208118 (Counterclockwise)

Preceding gene: 218928233

Following gene: 218928211

Centisome position: 25.97

GC content: 49.43

Gene sequence:

>261_bases
ATGTCGATGAGTGAAGAGTATCAACCCATCAATTGTGATGACTACGATAATCTGGAACTCGCCTGCCAACATCACCTGAT
ACTGACGTTGAAGTTGAGAGGCGGTGAGATCGTAGAAGGCAAAGCCAGCGATCTGCTGCTGAGAAAAAAGGTCGAGTACC
TGATTGTCGAGCAAGAAGGGACAATGCGCGAATTGCGTCTGGACCATATCGCCAGCTTCAGTCACCCCGAAATTGGAACG
GTCGTAGTGAGCGCATCATAG

Upstream 100 bases:

>100_bases
GTATTGAAAGCATTGGACGAAGTTGCGGCTAACGACGCACTCCCGTCCTCCGTTAGGGAACAGGCGGCCTATGCCGCCGC
TAACTTATTGGTGAGCGATT

Downstream 100 bases:

>100_bases
TTTCCACTTCCTTGTGAAAAACGGGTCGCTGAAGAGCGGCCCGTTTTGCATTTATCCTATTTACATTTACCTGGCTTACA
TTTTACCCGACTTACCTTTA

Product: Rho-binding antiterminator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MSMSEEYQPINCDDYDNLELACQHHLILTLKLRGGEIVEGKASDLLLRKKVEYLIVEQEGTMRELRLDHIASFSHPEIGT
VVVSAS

Sequences:

>Translated_86_residues
MSMSEEYQPINCDDYDNLELACQHHLILTLKLRGGEIVEGKASDLLLRKKVEYLIVEQEGTMRELRLDHIASFSHPEIGT
VVVSAS
>Mature_85_residues
SMSEEYQPINCDDYDNLELACQHHLILTLKLRGGEIVEGKASDLLLRKKVEYLIVEQEGTMRELRLDHIASFSHPEIGTV
VVSAS

Specific function: Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination [H]

COG id: COG4568

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081698, Length=84, Percent_Identity=73.8095238095238, Blast_Score=133, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002730
- InterPro:   IPR009778 [H]

Pfam domain/function: PF07073 ROF [H]

EC number: NA

Molecular weight: Translated: 9728; Mature: 9597

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSEEYQPINCDDYDNLELACQHHLILTLKLRGGEIVEGKASDLLLRKKVEYLIVEQEG
CCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEECCCEEECCCCCHHHEECCEEEEEECCCC
TMRELRLDHIASFSHPEIGTVVVSAS
CHHHHHHHHHCCCCCCCCCEEEEECC
>Mature Secondary Structure 
SMSEEYQPINCDDYDNLELACQHHLILTLKLRGGEIVEGKASDLLLRKKVEYLIVEQEG
CCCCCCCCCCCCCCCCEEEEEEEEEEEEEEECCCEEECCCCCHHHEECCEEEEEECCCC
TMRELRLDHIASFSHPEIGTVVVSAS
CHHHHHHHHHCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9723924; 9278503 [H]