Click here to switch to the map view.

The map label for this gene is ompH

Identifier: 218928221

GI number: 218928221

Start: 1195917

End: 1196414

Strand: Direct

Name: ompH

Synonym: YPO1053

Alternate gene names: 218928221

Gene position: 1195917-1196414 (Clockwise)

Preceding gene: 218928220

Following gene: 218928222

Centisome position: 25.7

GC content: 45.38

Gene sequence:

>498_bases
GTGAAAAAGTGGTTGTGTGCCGCAAGTCTAGGTTTAGCATTGGCTGCTTCAGCCAGCGTTCAAGCAGCTGACAAAATTGC
TATTGTTAATGTTTCCAGCATTTTCCAACAATTACCCGCGCGTGAAGCCGTGGCTAAGCAGCTGGAGAATGAATTCAAAG
GCCGTGCAACCGAACTGCAAGGAATGGAGCGCGATCTGCAGACTAAAATGCAGAAGCTACAACGTGATGGTTCTACCATG
AAAGCCAGTGATCGTACCAAGCTGGAAAATGAAGTAATGAAACAGCGTGAAACTTTCTCTACTAAAGCGCAGGCTTTTGA
GCAAGATAACCGCCGTCGTCAGGCAGAAGAGCGTAACAAAATCCTGAGCCGTATTCAGGATGCTGTTAAATCTGTTGCTA
CCAAAGGTGGCTATGACGTAGTCATTGATGCGAATGCAGTGGCATACGCTGATTCTTCTAAAGACATTACTGCTGACGTA
TTGAAACAGGTTAAATAA

Upstream 100 bases:

>100_bases
AGTCGCGTTGGTGAAATCTGACGCTTCATCAGGTGGGATACACTACCAAGTGCAATTCAAGGTGTCTCTGACACAAACGG
GTAATGGTAAGGAGTTTATA

Downstream 100 bases:

>100_bases
AACATGCCTTCAATTCGACTGGCTGATTTAGCCCAGCAGTTGGATGCACAGGTGCACGGTGATGGCGATCTTGTCATCAC
CGGCATCGCTTCTATGCATT

Product: periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTM
KASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADV
LKQVK

Sequences:

>Translated_165_residues
MKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTM
KASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADV
LKQVK
>Mature_165_residues
MKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTM
KASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADV
LKQVK

Specific function: Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm

COG id: COG2825

COG function: function code M; Outer membrane protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the skp family

Homologues:

Organism=Escherichia coli, GI1786375, Length=167, Percent_Identity=67.6646706586826, Blast_Score=180, Evalue=4e-47,

Paralogues:

None

Copy number: 580 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SKP_YERPE (P58607)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AD0129
- RefSeq:   NP_670425.1
- RefSeq:   NP_994104.1
- RefSeq:   YP_002346096.1
- ProteinModelPortal:   P58607
- SMR:   P58607
- GeneID:   1148073
- GeneID:   1173893
- GeneID:   2765720
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1053
- KEGG:   ypk:y3126
- KEGG:   ypm:YP_2797
- HOGENOM:   HBG495360
- OMA:   AVYVNPR
- ProtClustDB:   PRK10780
- BioCyc:   YPES187410:Y3126-MONOMER
- BioCyc:   YPES214092:YPO1053-MONOMER
- InterPro:   IPR005632
- SMART:   SM00935

Pfam domain/function: PF03938 OmpH; SSF111384 OM_chaperone_Skp/OmpH

EC number: NA

Molecular weight: Translated: 18279; Mature: 18279

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHEEEHHHHHHHCCHHHHHHHHHHHHHCCHHHHHH
GMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADVLKQVK
HHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHEEEHHHHHHHCCHHHHHHHHHHHHHCCHHHHHH
GMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADVLKQVK
HHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430