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The map label for this gene is tas [H]

Identifier: 218927970

GI number: 218927970

Start: 865946

End: 866986

Strand: Direct

Name: tas [H]

Synonym: YPO0790

Alternate gene names: 218927970

Gene position: 865946-866986 (Clockwise)

Preceding gene: 218927969

Following gene: 218927975

Centisome position: 18.61

GC content: 50.14

Gene sequence:

>1041_bases
ATGCAATATCATCGTATCCCCCACAGTTCATTGGAAGTAAGCCTGCTGGGTCTGGGCACCATGACGTTTGGTGAGCAAAA
CAGTGAAGCCGATGCCCACGCTCAACTGGATTATGCCGTTGCAGCCGGTATTAACTTGATTGATACCGCAGAAATGTACC
CGGTGCCTCCAAGGCCAGAAACTCAGGGATTAACTGAGCAATATATTGGTCGCTGGATAAAAGCACGCGGTTGCCGCGAA
AAAATTATTTTAGCCAGTAAAGTCTCCGGGCCATCACGCGGTGATGATCAGCCCATTCGCCCGAATATGGCATTGGATCG
GAAGAATATCCGCATCGCGCTGGAAGAGAGCCTTAAGCGCCTTAATACCGATTATCTTGATATTTATCAGTTACATTGGC
CTCAGCGGGAAACAAACTGTTTCGGTAAGCTGAATTATCGCTATAGCGAGCAAACTGCCGTTGTGACCTTGCTGGAAACA
CTGGAAGCCCTGAACGAGCAAGTGCGGGCCGGTAAAATTCGTTATATCGGGGTATCCAATGAAACACCATGGGGTGTCAT
GCGTTATCTGCAACTGGCAGAAAAGCATGATCTACCGCGTATCGTCTCTATTCAGAACCCTTACAGCCTGTTAAACCGTA
GCTTTGAAGTGGGTCTGGCAGAGATTAGCCAGCACGAAGGCGTTGAGTTATTAGCTTATTCCAGCCTGGCTTTTGGCACA
CTGAGCGGCAAATACCTTAATGGCGCGAAACCTGCCGGTGCACGCAACACCTTGTTCAGCCGTTTCACCCGTTACTCTGG
GCCACAAACCCAATTAGCGGTGGCTGAATATGTGTCGCTGGCAAAACACCATGGGCTGGATCCGGCGCAGATGGCTCTGG
CCTTTGTGCGGCAACAGCCGTTTGTTGCCAGTACGCTACTCGGCGCAACGTCGCTGGAACAACTGAAAAGTAATATTGAT
AGCCAAAATATCGTGCTGAGTCAGGAAGTACTGGATGCACTGGAAGCGATCCATACCCGCTATACCTTCCCCGCACCTTA
A

Upstream 100 bases:

>100_bases
GGCGTTGAGTCAACGCAGCTAACAACGCTGCAACATCAAAAACGAAGGGTATGACCTGACAATTTCAGACACAAGATTCA
GACACAAAGGAAGGTCGGCA

Downstream 100 bases:

>100_bases
ATCTTGTCGTAGCCCCTATCATCCCTATCATAATATGAAGGCCGCTGATGCGGCCTTGAGGTTATTGACAAAGTGTCAAC
GACGGAGAGAACAGGCAGAT

Product: putative aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQYHRIPHSSLEVSLLGLGTMTFGEQNSEADAHAQLDYAVAAGINLIDTAEMYPVPPRPETQGLTEQYIGRWIKARGCRE
KIILASKVSGPSRGDDQPIRPNMALDRKNIRIALEESLKRLNTDYLDIYQLHWPQRETNCFGKLNYRYSEQTAVVTLLET
LEALNEQVRAGKIRYIGVSNETPWGVMRYLQLAEKHDLPRIVSIQNPYSLLNRSFEVGLAEISQHEGVELLAYSSLAFGT
LSGKYLNGAKPAGARNTLFSRFTRYSGPQTQLAVAEYVSLAKHHGLDPAQMALAFVRQQPFVASTLLGATSLEQLKSNID
SQNIVLSQEVLDALEAIHTRYTFPAP

Sequences:

>Translated_346_residues
MQYHRIPHSSLEVSLLGLGTMTFGEQNSEADAHAQLDYAVAAGINLIDTAEMYPVPPRPETQGLTEQYIGRWIKARGCRE
KIILASKVSGPSRGDDQPIRPNMALDRKNIRIALEESLKRLNTDYLDIYQLHWPQRETNCFGKLNYRYSEQTAVVTLLET
LEALNEQVRAGKIRYIGVSNETPWGVMRYLQLAEKHDLPRIVSIQNPYSLLNRSFEVGLAEISQHEGVELLAYSSLAFGT
LSGKYLNGAKPAGARNTLFSRFTRYSGPQTQLAVAEYVSLAKHHGLDPAQMALAFVRQQPFVASTLLGATSLEQLKSNID
SQNIVLSQEVLDALEAIHTRYTFPAP
>Mature_346_residues
MQYHRIPHSSLEVSLLGLGTMTFGEQNSEADAHAQLDYAVAAGINLIDTAEMYPVPPRPETQGLTEQYIGRWIKARGCRE
KIILASKVSGPSRGDDQPIRPNMALDRKNIRIALEESLKRLNTDYLDIYQLHWPQRETNCFGKLNYRYSEQTAVVTLLET
LEALNEQVRAGKIRYIGVSNETPWGVMRYLQLAEKHDLPRIVSIQNPYSLLNRSFEVGLAEISQHEGVELLAYSSLAFGT
LSGKYLNGAKPAGARNTLFSRFTRYSGPQTQLAVAEYVSLAKHHGLDPAQMALAFVRQQPFVASTLLGATSLEQLKSNID
SQNIVLSQEVLDALEAIHTRYTFPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=347, Percent_Identity=28.2420749279539, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI27436964, Length=348, Percent_Identity=28.1609195402299, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4504825, Length=345, Percent_Identity=28.1159420289855, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI27436962, Length=348, Percent_Identity=28.1609195402299, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI27436966, Length=348, Percent_Identity=27.8735632183908, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI27436971, Length=340, Percent_Identity=29.1176470588235, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=77.7456647398844, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI87081735, Length=344, Percent_Identity=30.5232558139535, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=31.2312312312312, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788070, Length=356, Percent_Identity=29.4943820224719, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788081, Length=254, Percent_Identity=33.0708661417323, Blast_Score=85, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=322, Percent_Identity=27.0186335403727, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=348, Percent_Identity=27.0114942528736, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=268, Percent_Identity=25.7462686567164, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=343, Percent_Identity=23.6151603498542, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=22.5352112676056, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320576, Length=318, Percent_Identity=25.7861635220126, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38659; Mature: 38659

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYHRIPHSSLEVSLLGLGTMTFGEQNSEADAHAQLDYAVAAGINLIDTAEMYPVPPRPE
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCC
TQGLTEQYIGRWIKARGCREKIILASKVSGPSRGDDQPIRPNMALDRKNIRIALEESLKR
CCCHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHH
LNTDYLDIYQLHWPQRETNCFGKLNYRYSEQTAVVTLLETLEALNEQVRAGKIRYIGVSN
HCCCCEEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
ETPWGVMRYLQLAEKHDLPRIVSIQNPYSLLNRSFEVGLAEISQHEGVELLAYSSLAFGT
CCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHHHHHHHCCCEEEEEECCHHHCC
LSGKYLNGAKPAGARNTLFSRFTRYSGPQTQLAVAEYVSLAKHHGLDPAQMALAFVRQQP
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
FVASTLLGATSLEQLKSNIDSQNIVLSQEVLDALEAIHTRYTFPAP
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQYHRIPHSSLEVSLLGLGTMTFGEQNSEADAHAQLDYAVAAGINLIDTAEMYPVPPRPE
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCC
TQGLTEQYIGRWIKARGCREKIILASKVSGPSRGDDQPIRPNMALDRKNIRIALEESLKR
CCCHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHH
LNTDYLDIYQLHWPQRETNCFGKLNYRYSEQTAVVTLLETLEALNEQVRAGKIRYIGVSN
HCCCCEEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
ETPWGVMRYLQLAEKHDLPRIVSIQNPYSLLNRSFEVGLAEISQHEGVELLAYSSLAFGT
CCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHHHHHHHCCCEEEEEECCHHHCC
LSGKYLNGAKPAGARNTLFSRFTRYSGPQTQLAVAEYVSLAKHHGLDPAQMALAFVRQQP
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
FVASTLLGATSLEQLKSNIDSQNIVLSQEVLDALEAIHTRYTFPAP
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]