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The map label for this gene is rppH [H]

Identifier: 218927966

GI number: 218927966

Start: 863700

End: 864227

Strand: Reverse

Name: rppH [H]

Synonym: YPO0786

Alternate gene names: 218927966

Gene position: 864227-863700 (Counterclockwise)

Preceding gene: 218927967

Following gene: 218927965

Centisome position: 18.57

GC content: 47.73

Gene sequence:

>528_bases
GTGATCGATGATGATGGCTACCGCCCGAATGTGGGTATTGTAATTTGTAATCGGCAGGGTGAAGTATTGTGGGCCAGGCG
CTATGGACAGCACTCTTGGCAGTTTCCTCAAGGGGGAATAAATCCCGGTGAGACACCCGAGCAGGCGATGTACCGTGAAC
TTTTTGAAGAAGTAGGATTGAACAAAAAGGATGTTCGGATATTGGCTTCAACCCGTAATTGGTTGCGTTACAAATTACCA
AAACGTTTGGTGCGTTGGGATACAAAGCCGGTGTGTATCGGCCAAAAACAGCGGTGGTTCTTACTACAGTTAATGTGTAA
CGAAGCCGAGATTAATATGCAACGTAGCAGTACACCAGAATTTGATGGCTGGCGTTGGGTCAGCTACTGGTATCCGGTTC
GTCAAGTGGTGTCTTTTAAACGTGATGTTTATCGTCGTGTAATGAAAGAATTTGCTGCAACCGTAATGCCTGTGCAGGAG
GTCGCTCCTCCACGGGTACCGCCCGCTTATCGCCGTAAAAGAGGTTAA

Upstream 100 bases:

>100_bases
GTTATCAGGTTTGGCCGGCTGATAAGCAGTGGTTTACCGCCTGTTGCTAGTGTGAAACAATCAGAGCATCTTTGAGTTTT
GAGCTTATCGAGGTAGTCCG

Downstream 100 bases:

>100_bases
GTTAAGCCGATCATGCTCATGCGTTTGCGAGAAGTAGTTGAGAAAGTGGCGATGGCAACCGGCCTGACGGAGGCGTTAGA
GCTGTTGGTCAATGAAACCT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGLNKKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQE
VAPPRVPPAYRRKRG

Sequences:

>Translated_175_residues
MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGLNKKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQE
VAPPRVPPAYRRKRG
>Mature_175_residues
MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGLNKKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQE
VAPPRVPPAYRRKRG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=176, Percent_Identity=86.3636363636364, Blast_Score=318, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20893; Mature: 20893

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGL
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
NKKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPE
CHHHHEEEECHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCHHHEEECCCCCCC
FDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQEVAPPRVPPAYRRKRG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure
MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGL
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
NKKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPE
CHHHHEEEECHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCHHHEEECCCCCCC
FDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQEVAPPRVPPAYRRKRG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA